Detailed information NTG0517327

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: I6I02_RS00125
• Genome accession: NZ_CP066093
• Coordinates: 33783..34883 (+)
• Length: 366 a.a.
• NCBI ID: WP_198463594.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_1045
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 28783..39883

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I02_RS00115 (I6I02_00115)	-	32517..32879 (+)	363	WP_002887019.1	DUF1033 family protein	-
I6I02_RS00120 (I6I02_00120)	comGA/cglA/cilD	32960..33901 (+)	942	WP_060971595.1	competence type IV pilus ATPase ComGA	Machinery gene
I6I02_RS00125 (I6I02_00125)	comYB	33783..34883 (+)	1101	WP_198463594.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6I02_RS00130 (I6I02_00130)	comYC	34880..35206 (+)	327	WP_002885815.1	competence type IV pilus major pilin ComGC	Machinery gene
I6I02_RS00135 (I6I02_00135)	comYD	35166..35594 (+)	429	WP_269780043.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6I02_RS00140 (I6I02_00140)	comGE	35626..35856 (+)	231	WP_051412000.1	competence type IV pilus minor pilin ComGE	-
I6I02_RS00145 (I6I02_00145)	comYF	35843..36280 (+)	438	WP_037601472.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6I02_RS00150 (I6I02_00150)	comGG	36258..36575 (+)	318	WP_041817287.1	competence type IV pilus minor pilin ComGG	-
I6I02_RS00155 (I6I02_00155)	comYH	36620..37576 (+)	957	WP_013991262.1	class I SAM-dependent methyltransferase	Machinery gene
I6I02_RS00160 (I6I02_00160)	-	37633..38826 (+)	1194	WP_003095894.1	acetate kinase	-
I6I02_RS00165 (I6I02_00165)	-	39077..39274 (+)	198	WP_013991261.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41645.74 Da
• Isoelectric Point: 10.1481

>NTDB_id=517327 I6I02_RS00125 WP_198463594.1 33783..34883(+) (comYB) [Streptococcus salivarius strain FDAARGOS_1045]
MPVKISKVIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLAEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSKLFRELGADLEKALMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=517327 I6I02_RS00125 WP_198463594.1 33783..34883(+) (comYB) [Streptococcus salivarius strain FDAARGOS_1045]
TTGCCAGTGAAAATTTCCAAAGTCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGACATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAGCTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGCATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCCCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAATCAAAGCTCTTTCGTGAGCT
GGGGGCTGATTTAGAGAAAGCCTTGATGCTAGGACAGAGTTTTCCTGACCGAATTGCTAGTCATCCATTTTTCACTAAGG
AGCTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	55.102	93.716	0.516
comYB	Streptococcus mutans UA159	55.102	93.716	0.516
comYB	Streptococcus gordonii str. Challis substr. CH1	51.603	93.716	0.484
comGB/cglB	Streptococcus mitis NCTC 12261	49.856	94.809	0.473
comGB/cglB	Streptococcus mitis SK321	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae Rx1	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae D39	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae R6	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae TIGR4	49.112	92.35	0.454
comGB	Lactococcus lactis subsp. cremoris KW2	45.646	90.984	0.415