Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   I6I32_RS04370 Genome accession   NZ_CP066041
Coordinates   902978..903919 (-) Length   313 a.a.
NCBI ID   WP_198465002.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 897978..908919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS04330 (I6I32_04330) comYH 898590..899543 (-) 954 WP_198464998.1 class I SAM-dependent methyltransferase Machinery gene
  I6I32_RS04335 (I6I32_04335) - 899602..900192 (-) 591 WP_198464999.1 class I SAM-dependent methyltransferase -
  I6I32_RS04340 (I6I32_04340) comGG/cglG 900197..900625 (-) 429 WP_049478131.1 competence type IV pilus minor pilin ComGG Machinery gene
  I6I32_RS04345 (I6I32_04345) comGF/cglF 900603..901064 (-) 462 WP_198465000.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6I32_RS04350 (I6I32_04350) comGE/cglE 901027..901329 (-) 303 WP_000413375.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6I32_RS04355 (I6I32_04355) comGD/cglD 901292..901726 (-) 435 WP_198465001.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6I32_RS04360 (I6I32_04360) comGC/cglC 901689..902012 (-) 324 WP_000735798.1 competence type IV pilus major pilin ComGC Machinery gene
  I6I32_RS04365 (I6I32_04365) comGB/cglB 902014..903030 (-) 1017 WP_198465068.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6I32_RS04370 (I6I32_04370) comGA/cglA/cilD 902978..903919 (-) 942 WP_198465002.1 competence type IV pilus ATPase ComGA Machinery gene
  I6I32_RS04375 (I6I32_04375) - 903980..904345 (-) 366 WP_000286399.1 DUF1033 family protein -
  I6I32_RS04380 (I6I32_04380) nagA 904498..905649 (-) 1152 WP_198465003.1 N-acetylglucosamine-6-phosphate deacetylase -
  I6I32_RS04385 (I6I32_04385) - 905790..907607 (-) 1818 WP_001220886.1 acyltransferase family protein -
  I6I32_RS04390 (I6I32_04390) tgt 907741..908883 (-) 1143 WP_001285237.1 tRNA guanosine(34) transglycosylase Tgt -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35441.36 Da        Isoelectric Point: 5.7866

>NTDB_id=516654 I6I32_RS04370 WP_198465002.1 902978..903919(-) (comGA/cglA/cilD) [Streptococcus oralis strain FDAARGOS_1075]
MVQEIAQKIIATAKEKKAQDIYFIPKEKSYELHMRVGDERCLVDSYEFDVLAAVISHFKFVAGMNVGEKRRSQLGSCDYQ
HGEKVSSLRLSTVGDYRGHESLVIRLLHDEERDLHFWFQDVNELGEQYRQRGLYLFAGPVGSGKTTLMHELAKSLFKGQQ
VMSIEDPVEIKQEDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVTEEELAVVLQGVCYQRLIGGGGIVDFANKDFQEHQPTSWNAQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=516654 I6I32_RS04370 WP_198465002.1 902978..903919(-) (comGA/cglA/cilD) [Streptococcus oralis strain FDAARGOS_1075]
ATGGTACAAGAAATTGCACAGAAAATTATTGCTACTGCGAAAGAAAAGAAGGCTCAGGATATCTATTTTATCCCCAAGGA
AAAGTCCTACGAGCTTCACATGCGGGTTGGAGACGAACGGTGTCTAGTTGACTCCTATGAGTTTGATGTTTTAGCTGCTG
TGATTAGTCATTTTAAGTTTGTAGCGGGTATGAATGTAGGGGAGAAGAGACGTAGTCAGCTGGGATCTTGCGACTATCAG
CATGGGGAGAAGGTGTCTTCTCTGCGTTTATCTACCGTAGGAGATTATCGGGGACATGAGAGTTTGGTTATTCGTTTGTT
GCACGATGAGGAGCGGGACCTGCATTTCTGGTTTCAGGATGTGAATGAACTGGGTGAGCAGTACCGGCAACGGGGCCTCT
ACCTTTTTGCGGGTCCAGTCGGAAGTGGCAAGACGACCTTGATGCACGAATTGGCCAAGTCACTTTTTAAGGGGCAACAG
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGAAGACATGCTCCAGTTGCAGTTGAATGAAGCGATTGGCTTGAC
CTATGAAAATCTGATCAAACTGTCTCTCCGGCATCGTCCGGACCTCTTGATTATCGGTGAAATTCGGGATAGTGAGACGG
CGCGTGCGGTTGTCAGAGCCAGTTTGACAGGGGCGACAGTCTTTTCAACCATTCATGCCAAGAGTATCCGAGGTGTTTAT
GAACGCCTTCTGGAGTTGGGTGTGACGGAGGAGGAATTAGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATTGG
GGGAGGAGGAATCGTTGACTTTGCAAACAAAGACTTTCAAGAACACCAGCCAACCAGCTGGAATGCGCAGATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

89.457

100

0.895
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

87.859

100

0.879
  comGA/cglA/cilD Streptococcus pneumoniae D39

87.859

100

0.879
  comGA/cglA/cilD Streptococcus pneumoniae R6

87.859

100

0.879
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

87.859

100

0.879
  comYA Streptococcus gordonii str. Challis substr. CH1

78.065

99.042

0.773
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.968

99.042

0.604
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

44.061

83.387

0.367