Detailed information NTG0516652

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: I6I32_RS04360
• Genome accession: NZ_CP066041
• Coordinates: 901689..902012 (-)
• Length: 107 a.a.
• NCBI ID: WP_000735798.1
• Uniprot ID: A0A1X1HB54
• Organism: Streptococcus oralis strain FDAARGOS_1075
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 896689..907012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I32_RS04320 (I6I32_04320)	rnpA	896827..897198 (-)	372	WP_045591913.1	ribonuclease P protein component	-
I6I32_RS04325 (I6I32_04325)	-	897348..898538 (-)	1191	WP_000167789.1	acetate kinase	-
I6I32_RS04330 (I6I32_04330)	comYH	898590..899543 (-)	954	WP_198464998.1	class I SAM-dependent methyltransferase	Machinery gene
I6I32_RS04335 (I6I32_04335)	-	899602..900192 (-)	591	WP_198464999.1	class I SAM-dependent methyltransferase	-
I6I32_RS04340 (I6I32_04340)	comGG/cglG	900197..900625 (-)	429	WP_049478131.1	competence type IV pilus minor pilin ComGG	Machinery gene
I6I32_RS04345 (I6I32_04345)	comGF/cglF	900603..901064 (-)	462	WP_198465000.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6I32_RS04350 (I6I32_04350)	comGE/cglE	901027..901329 (-)	303	WP_000413375.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6I32_RS04355 (I6I32_04355)	comGD/cglD	901292..901726 (-)	435	WP_198465001.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6I32_RS04360 (I6I32_04360)	comGC/cglC	901689..902012 (-)	324	WP_000735798.1	competence type IV pilus major pilin ComGC	Machinery gene
I6I32_RS04365 (I6I32_04365)	comGB/cglB	902014..903030 (-)	1017	WP_198465068.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6I32_RS04370 (I6I32_04370)	comGA/cglA/cilD	902978..903919 (-)	942	WP_198465002.1	competence type IV pilus ATPase ComGA	Machinery gene
I6I32_RS04375 (I6I32_04375)	-	903980..904345 (-)	366	WP_000286399.1	DUF1033 family protein	-
I6I32_RS04380 (I6I32_04380)	nagA	904498..905649 (-)	1152	WP_198465003.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 11891.03 Da
• Isoelectric Point: 10.1883

>NTDB_id=516652 I6I32_RS04360 WP_000735798.1 901689..902012(-) (comGC/cglC) [Streptococcus oralis strain FDAARGOS_1075]
MKKLMTNLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVDDKGKAAVVKVVESQAELYRLDKNDDASLSKLQA
DGRITAEQAKAYKDYHAKQKTSQTVAD

Nucleotide

• Length: 324 bp

>NTDB_id=516652 I6I32_RS04360 WP_000735798.1 901689..902012(-) (comGC/cglC) [Streptococcus oralis strain FDAARGOS_1075]
ATGAAAAAACTCATGACAAATTTAAAAAAAGCCAAGGTTAAAGCTTTCACTTTGGTAGAAATGTTAGTGGTCTTGCTCAT
CATCAGCGTTCTTCTCTTGCTCTTTGTGCCCAATTTGACCAAGCAAAAGGATGCCGTAGATGATAAAGGAAAAGCTGCTG
TTGTCAAGGTCGTGGAAAGCCAGGCAGAACTTTATCGTTTGGATAAAAATGATGATGCCAGCCTCAGCAAATTACAAGCG
GACGGTCGTATCACAGCTGAGCAAGCTAAAGCTTACAAAGACTACCATGCAAAACAAAAAACCAGTCAAACTGTTGCAGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

3D structure

• AlphaFold DB: A0A1X1HB54

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	91.589	100	0.916
comGC/cglC	Streptococcus mitis SK321	88.889	92.523	0.822
comGC/cglC	Streptococcus pneumoniae R6	86.869	92.523	0.804
comGC/cglC	Streptococcus pneumoniae Rx1	86.869	92.523	0.804
comGC/cglC	Streptococcus pneumoniae D39	86.869	92.523	0.804
comGC/cglC	Streptococcus pneumoniae TIGR4	85.859	92.523	0.794
comYC	Streptococcus gordonii str. Challis substr. CH1	67.619	98.131	0.664
comYC	Streptococcus mutans UA140	70.103	90.654	0.636
comYC	Streptococcus mutans UA159	70.103	90.654	0.636
comGC	Lactococcus lactis subsp. cremoris KW2	57.426	94.393	0.542
comYC	Streptococcus suis isolate S10	65.909	82.243	0.542