Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   I6I32_RS04350 Genome accession   NZ_CP066041
Coordinates   901027..901329 (-) Length   100 a.a.
NCBI ID   WP_000413375.1    Uniprot ID   F2QGL3
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 896027..906329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS04320 (I6I32_04320) rnpA 896827..897198 (-) 372 WP_045591913.1 ribonuclease P protein component -
  I6I32_RS04325 (I6I32_04325) - 897348..898538 (-) 1191 WP_000167789.1 acetate kinase -
  I6I32_RS04330 (I6I32_04330) comYH 898590..899543 (-) 954 WP_198464998.1 class I SAM-dependent methyltransferase Machinery gene
  I6I32_RS04335 (I6I32_04335) - 899602..900192 (-) 591 WP_198464999.1 class I SAM-dependent methyltransferase -
  I6I32_RS04340 (I6I32_04340) comGG/cglG 900197..900625 (-) 429 WP_049478131.1 competence type IV pilus minor pilin ComGG Machinery gene
  I6I32_RS04345 (I6I32_04345) comGF/cglF 900603..901064 (-) 462 WP_198465000.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6I32_RS04350 (I6I32_04350) comGE/cglE 901027..901329 (-) 303 WP_000413375.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6I32_RS04355 (I6I32_04355) comGD/cglD 901292..901726 (-) 435 WP_198465001.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6I32_RS04360 (I6I32_04360) comGC/cglC 901689..902012 (-) 324 WP_000735798.1 competence type IV pilus major pilin ComGC Machinery gene
  I6I32_RS04365 (I6I32_04365) comGB/cglB 902014..903030 (-) 1017 WP_198465068.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6I32_RS04370 (I6I32_04370) comGA/cglA/cilD 902978..903919 (-) 942 WP_198465002.1 competence type IV pilus ATPase ComGA Machinery gene
  I6I32_RS04375 (I6I32_04375) - 903980..904345 (-) 366 WP_000286399.1 DUF1033 family protein -
  I6I32_RS04380 (I6I32_04380) nagA 904498..905649 (-) 1152 WP_198465003.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11153.08 Da        Isoelectric Point: 7.0157

>NTDB_id=516650 I6I32_RS04350 WP_000413375.1 901027..901329(-) (comGE/cglE) [Streptococcus oralis strain FDAARGOS_1075]
MEKLNALRKQKIKAVILLEAVVALAVFASIATLLLGQIQKNRQEEAEILQKEEVLRVAKMALQTGQNQVNINGVEIQVFA
SEKGLEVYHGSEKLLDLKEQ

Nucleotide


Download         Length: 303 bp        

>NTDB_id=516650 I6I32_RS04350 WP_000413375.1 901027..901329(-) (comGE/cglE) [Streptococcus oralis strain FDAARGOS_1075]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAAGGCAGTGATTTTACTGGAAGCGGTAGTTGCTCTAGCCGTTTT
TGCCAGCATTGCGACCCTTCTTTTGGGACAAATCCAGAAAAATAGGCAGGAAGAGGCAGAAATCTTGCAAAAGGAAGAAG
TCTTACGTGTAGCTAAGATGGCTCTGCAGACAGGTCAAAATCAGGTAAACATAAATGGAGTGGAGATTCAGGTGTTTGCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAGAAGTTGCTGGATCTTAAAGAGCAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QGL3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae Rx1

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae D39

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae R6

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae TIGR4

91.919

99

0.91
  comGE/cglE Streptococcus mitis SK321

90.909

99

0.9
  comYE Streptococcus mutans UA140

43.478

92

0.4
  comYE Streptococcus mutans UA159

43.478

92

0.4