Detailed information NTG0051106

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: SPAF_RS01605
• Genome accession: NC_017905
• Coordinates: 305038..305355 (+)
• Length: 105 a.a.
• NCBI ID: WP_003019171.1
• Uniprot ID: F8DGZ2
• Organism: Streptococcus parasanguinis FW213
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 300038..310355

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPAF_RS01585 (Spaf_0282)	-	301329..302432 (+)	1104	WP_014712775.1	glycosyl hydrolase family 8	-
SPAF_RS01590 (Spaf_0283)	-	302658..303050 (+)	393	WP_041826517.1	DUF1033 family protein	-
SPAF_RS01595 (Spaf_0284)	comYA	303136..304077 (+)	942	WP_003019098.1	competence type IV pilus ATPase ComGA	Machinery gene
SPAF_RS01600 (Spaf_0286)	comYB	304010..305041 (+)	1032	WP_115276785.1	competence type IV pilus assembly protein ComGB	Machinery gene
SPAF_RS01605 (Spaf_0287)	comYC	305038..305355 (+)	318	WP_003019171.1	competence type IV pilus major pilin ComGC	Machinery gene
SPAF_RS01610 (Spaf_0288)	comYD	305345..305749 (+)	405	WP_003004513.1	competence type IV pilus minor pilin ComGD	Machinery gene
SPAF_RS01615 (Spaf_0289)	comGE	305715..306002 (+)	288	WP_041826198.1	competence type IV pilus minor pilin ComGE	-
SPAF_RS01620 (Spaf_0290)	comGF/cglF	305992..306444 (+)	453	WP_003019060.1	competence type IV pilus minor pilin ComGF	Machinery gene
SPAF_RS01625 (Spaf_0291)	comGG	306401..306868 (+)	468	WP_014712781.1	competence type IV pilus minor pilin ComGG	-
SPAF_RS01630 (Spaf_0292)	comYH	306899..307852 (+)	954	WP_014712782.1	class I SAM-dependent methyltransferase	Machinery gene
SPAF_RS01635 (Spaf_0293)	-	307904..309097 (+)	1194	WP_013904491.1	acetate kinase	-
SPAF_RS01640 (Spaf_0294)	-	309170..309901 (+)	732	WP_014712783.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11675.59 Da
• Isoelectric Point: 9.6248

>NTDB_id=51106 SPAF_RS01605 WP_003019171.1 305038..305355(+) (comYC) [Streptococcus parasanguinis FW213]
MKKLKTYKVKAFTLIEMLVVLLIISVLLLLFVPNLTKQKDSVKETGNAAVVKVVESQAELYELNHTNDQATLAKLIADGN
ITNKQAESYRSYYAKNSGETRAVAD

Nucleotide

• Length: 318 bp

>NTDB_id=51106 SPAF_RS01605 WP_003019171.1 305038..305355(+) (comYC) [Streptococcus parasanguinis FW213]
ATGAAAAAATTAAAAACCTATAAGGTAAAGGCCTTTACACTTATTGAAATGTTGGTGGTCTTATTGATCATCAGTGTGCT
CTTATTGCTCTTTGTGCCGAATTTGACCAAGCAAAAAGACTCCGTGAAAGAGACAGGAAATGCAGCGGTTGTGAAGGTGG
TCGAAAGTCAGGCTGAATTGTACGAGCTCAATCATACCAATGACCAAGCCACTCTAGCAAAACTGATTGCTGATGGAAAT
ATTACCAACAAACAAGCAGAATCCTACCGTTCCTATTATGCGAAAAATAGTGGAGAAACTCGTGCGGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: F8DGZ2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	75.238	100	0.752
comYC	Streptococcus mutans UA159	73.333	100	0.733
comYC	Streptococcus mutans UA140	73.333	100	0.733
comGC/cglC	Streptococcus mitis SK321	67.89	100	0.705
comGC/cglC	Streptococcus mitis NCTC 12261	66.364	100	0.695
comGC/cglC	Streptococcus pneumoniae Rx1	65.138	100	0.676
comGC/cglC	Streptococcus pneumoniae R6	65.138	100	0.676
comGC/cglC	Streptococcus pneumoniae TIGR4	65.138	100	0.676
comGC/cglC	Streptococcus pneumoniae D39	65.138	100	0.676
comGC	Lactococcus lactis subsp. cremoris KW2	59.615	99.048	0.59
comYC	Streptococcus suis isolate S10	67.416	84.762	0.571
comGC	Staphylococcus aureus N315	45.918	93.333	0.429
comGC	Staphylococcus aureus MW2	45.918	93.333	0.429