Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SPAF_RS01595 Genome accession   NC_017905
Coordinates   303136..304077 (+) Length   313 a.a.
NCBI ID   WP_003019098.1    Uniprot ID   -
Organism   Streptococcus parasanguinis FW213     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 298136..309077
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPAF_RS01575 (Spaf_0280) - 299078..299867 (+) 790 Protein_269 hypothetical protein -
  SPAF_RS01580 (Spaf_0281) - 300010..301320 (+) 1311 WP_003019113.1 glycosyltransferase -
  SPAF_RS01585 (Spaf_0282) - 301329..302432 (+) 1104 WP_014712775.1 glycosyl hydrolase family 8 -
  SPAF_RS01590 (Spaf_0283) - 302658..303050 (+) 393 WP_041826517.1 DUF1033 family protein -
  SPAF_RS01595 (Spaf_0284) comYA 303136..304077 (+) 942 WP_003019098.1 competence type IV pilus ATPase ComGA Machinery gene
  SPAF_RS01600 (Spaf_0286) comYB 304010..305041 (+) 1032 WP_115276785.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPAF_RS01605 (Spaf_0287) comYC 305038..305355 (+) 318 WP_003019171.1 competence type IV pilus major pilin ComGC Machinery gene
  SPAF_RS01610 (Spaf_0288) comYD 305345..305749 (+) 405 WP_003004513.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPAF_RS01615 (Spaf_0289) comGE 305715..306002 (+) 288 WP_041826198.1 competence type IV pilus minor pilin ComGE -
  SPAF_RS01620 (Spaf_0290) comGF/cglF 305992..306444 (+) 453 WP_003019060.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPAF_RS01625 (Spaf_0291) comGG 306401..306868 (+) 468 WP_014712781.1 competence type IV pilus minor pilin ComGG -
  SPAF_RS01630 (Spaf_0292) comYH 306899..307852 (+) 954 WP_014712782.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35884.28 Da        Isoelectric Point: 6.7636

>NTDB_id=51104 SPAF_RS01595 WP_003019098.1 303136..304077(+) (comYA) [Streptococcus parasanguinis FW213]
MVQEIAKKLIRMGKKEEAQDLYFVPRKEEYQVFMRVGDERRFVQSFPFEEMTAIISHFKFVAGMNVGEKRRSQLGSCDYP
LENGVVSIRLSTVGDYRGYESLVIRLLHDEERELRFWFDQLPDLKKKLAGRGLYLFAGPVGSGKTTLMHALAQERFADQQ
VMSIEDPVEIKQENMLQLQLNDQIGMTYDNLIKLSLRHRPDLLIIGEIRDKETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVSEEELKIVLQGICYQRLIAGGGVVDFATENYQEHSASRWNQQMDLLAQSGYIQLAQAQAEKIIYR

Nucleotide


Download         Length: 942 bp        

>NTDB_id=51104 SPAF_RS01595 WP_003019098.1 303136..304077(+) (comYA) [Streptococcus parasanguinis FW213]
ATGGTTCAAGAAATTGCAAAAAAATTGATCCGTATGGGGAAGAAGGAAGAAGCTCAGGATCTCTACTTCGTTCCTCGGAA
GGAGGAGTATCAGGTTTTTATGAGGGTCGGAGATGAGAGGCGTTTTGTGCAATCCTTTCCTTTTGAGGAGATGACGGCTA
TTATCAGCCATTTTAAATTTGTAGCAGGGATGAATGTGGGAGAAAAAAGGCGCAGCCAGCTAGGATCGTGTGATTACCCT
TTGGAGAATGGAGTGGTTTCGATTCGCTTGTCGACGGTGGGGGATTATCGTGGCTATGAAAGCTTGGTCATTCGGCTTTT
GCATGATGAGGAACGCGAATTGCGGTTTTGGTTTGATCAATTGCCAGACTTGAAGAAGAAATTGGCTGGTCGTGGGCTTT
ATCTCTTTGCGGGTCCCGTTGGTTCGGGAAAGACCACTCTCATGCATGCTCTGGCGCAAGAGCGCTTTGCAGATCAGCAA
GTCATGTCCATTGAAGATCCTGTCGAGATCAAGCAAGAGAATATGCTTCAGCTCCAGCTGAATGACCAGATCGGCATGAC
CTATGACAACCTGATCAAACTCTCCTTACGTCATCGACCGGATCTTCTCATTATTGGGGAGATCCGAGATAAGGAAACGG
CCCGTGCAGTTGTACGAGCTAGTTTGACAGGGGTCACCGTCTTCTCTACGATTCATGCCAAGAGCGTTAGAGGTGTTTAT
GAGCGCCTTTTAGAGCTTGGAGTGAGTGAGGAAGAACTCAAGATTGTTTTACAAGGTATTTGCTACCAACGATTAATTGC
AGGAGGAGGTGTTGTCGATTTTGCAACGGAAAACTACCAAGAGCACTCGGCCAGCCGCTGGAACCAACAAATGGATCTCT
TGGCTCAATCGGGATATATCCAGCTGGCTCAGGCGCAAGCCGAAAAAATTATCTACCGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(15-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

74.194

99.042

0.735
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

71.795

99.681

0.716
  comGA/cglA/cilD Streptococcus pneumoniae D39

71.474

99.681

0.712
  comGA/cglA/cilD Streptococcus pneumoniae R6

71.474

99.681

0.712
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

71.474

99.681

0.712
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

71.474

99.681

0.712
  comYA Streptococcus mutans UA159

64.309

99.361

0.639
  comYA Streptococcus mutans UA140

64.309

99.361

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

99.042

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

54.487

99.681

0.543
  comGA Latilactobacillus sakei subsp. sakei 23K

42.086

88.818

0.374

Multiple sequence alignment