Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX   Type   Regulator
Locus tag   ST4067_RS00870 Genome accession   NZ_CP065496
Coordinates   146342..146839 (+) Length   165 a.a.
NCBI ID   WP_002949220.1    Uniprot ID   A0A0M4HKA9
Organism   Streptococcus thermophilus strain 4067     
Function   activation of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 141290..145588 146342..146839 flank 754


Gene organization within MGE regions


Location: 141290..146839
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4067_RS00835 (ST4067_00820) - 141297..142111 (-) 815 Protein_109 ISL3 family transposase -
  ST4067_RS00840 (ST4067_00825) - 142404..142625 (+) 222 WP_002948904.1 DUF4649 family protein -
  ST4067_RS00845 (ST4067_00830) - 142714..143036 (-) 323 Protein_111 transposase -
  ST4067_RS00850 (ST4067_00835) - 143225..143680 (+) 456 WP_263604565.1 hypothetical protein -
  ST4067_RS00855 (ST4067_00840) - 143674..144864 (+) 1191 WP_164177854.1 SAM-dependent methyltransferase -
  ST4067_RS00860 (ST4067_00845) - 145124..145588 (-) 465 Protein_114 transposase family protein -
  ST4067_RS00865 (ST4067_00850) - 145946..146050 (+) 105 Protein_115 IS200/IS605 family transposase -
  ST4067_RS00870 (ST4067_00855) comX 146342..146839 (+) 498 WP_002949220.1 sigma factor Regulator

Sequence

Protein


Download         Length: 165 a.a.        Molecular weight: 20160.12 Da        Isoelectric Point: 5.2073

>NTDB_id=511056 ST4067_RS00870 WP_002949220.1 146342..146839(+) (comX) [Streptococcus thermophilus strain 4067]
MEQEVFVKAYEKVRPIVLKAFRQYFIQLWDQADMEQEAMMTLYQLLKKFPDLEKDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYVEISDIAFCIPNKELDMVDRLAYDEQLNAFREQLSSEDSLKLDRLLGGECFRGRKKMIRELRFWMVDFDP
CNEED

Nucleotide


Download         Length: 498 bp        

>NTDB_id=511056 ST4067_RS00870 WP_002949220.1 146342..146839(+) (comX) [Streptococcus thermophilus strain 4067]
ATGGAACAAGAAGTTTTTGTTAAGGCATATGAAAAGGTAAGGCCAATTGTACTTAAGGCTTTTAGGCAATACTTTATTCA
GCTTTGGGATCAAGCTGACATGGAGCAAGAGGCGATGATGACTTTGTATCAGCTTTTAAAAAAGTTTCCTGATTTAGAGA
AAGATGATGATAAGTTACGTCGTTACTTTAAAACTAAGTTTAGGAATCGACTTAATGATGAAGTGAGGCGGCAGGAGTCA
GTAAAACGTCAAGCTAATAGACAGTGCTATGTTGAAATTTCAGATATTGCCTTTTGTATTCCCAATAAGGAGCTAGATAT
GGTTGATAGACTTGCTTATGATGAACAGCTTAATGCTTTTCGTGAGCAGTTATCATCGGAAGATTCTCTTAAGTTGGATC
GATTGTTGGGTGGTGAATGCTTTAGGGGAAGGAAAAAGATGATACGAGAGTTAAGATTTTGGATGGTTGACTTTGATCCA
TGTAATGAAGAAGACTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(10-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M4HKA9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.