Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX   Type   Regulator
Locus tag   ST4145_RS00855 Genome accession   NZ_CP065492
Coordinates   145040..145537 (+) Length   165 a.a.
NCBI ID   WP_002949220.1    Uniprot ID   A0A0M4HKA9
Organism   Streptococcus thermophilus strain 4145     
Function   activation of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 140896..144286 145040..145537 flank 754


Gene organization within MGE regions


Location: 140896..145537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4145_RS00830 (ST4145_00820) - 140903..141807 (-) 905 Protein_109 ISL3 family transposase -
  ST4145_RS00835 (ST4145_00825) - 141965..142291 (+) 327 WP_014607875.1 M20/M25/M40 family metallo-hydrolase -
  ST4145_RS00840 (ST4145_00830) - 142373..143563 (+) 1191 WP_011680651.1 cyclopropane-fatty-acyl-phospholipid synthase family protein -
  ST4145_RS00845 (ST4145_00835) - 143822..144286 (-) 465 Protein_112 transposase family protein -
  ST4145_RS00850 (ST4145_00840) - 144644..144733 (+) 90 Protein_113 IS200/IS605 family transposase -
  ST4145_RS00855 (ST4145_00845) comX 145040..145537 (+) 498 WP_002949220.1 sigma factor Regulator

Sequence

Protein


Download         Length: 165 a.a.        Molecular weight: 20160.12 Da        Isoelectric Point: 5.2073

>NTDB_id=510875 ST4145_RS00855 WP_002949220.1 145040..145537(+) (comX) [Streptococcus thermophilus strain 4145]
MEQEVFVKAYEKVRPIVLKAFRQYFIQLWDQADMEQEAMMTLYQLLKKFPDLEKDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYVEISDIAFCIPNKELDMVDRLAYDEQLNAFREQLSSEDSLKLDRLLGGECFRGRKKMIRELRFWMVDFDP
CNEED

Nucleotide


Download         Length: 498 bp        

>NTDB_id=510875 ST4145_RS00855 WP_002949220.1 145040..145537(+) (comX) [Streptococcus thermophilus strain 4145]
ATGGAACAAGAAGTTTTTGTTAAGGCATATGAAAAGGTAAGGCCAATTGTACTTAAGGCTTTTAGGCAATACTTTATTCA
GCTTTGGGATCAAGCTGACATGGAGCAAGAGGCGATGATGACTTTGTATCAGCTTTTAAAAAAGTTTCCTGATTTAGAGA
AAGATGATGATAAGTTACGTCGTTACTTTAAAACTAAGTTTAGGAATCGACTTAATGATGAAGTGAGGCGGCAGGAGTCA
GTAAAACGTCAAGCTAATAGACAGTGCTATGTTGAAATTTCAGATATTGCCTTTTGTATTCCCAATAAGGAGCTAGATAT
GGTTGATAGACTTGCTTATGATGAACAGCTTAATGCTTTTCGTGAGCAGTTATCATCGGAAGATTCTCTTAAGTTGGATC
GATTGTTGGGTGGTGAATGCTTTAGGGGAAGGAAAAAGATGATACGAGAGTTAAGATTTTGGATGGTTGACTTTGATCCA
TGTAATGAAGAAGACTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(10-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M4HKA9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.