NTDB

Overview

Name	comGC/cglC	Type	Machinery gene
Locus tag	I2434_RS00760	Genome accession	NZ_CP065058
Coordinates	133111..133434 (+)	Length	107 a.a.
NCBI ID	WP_012514782.1	Uniprot ID	B4U056
Organism	Streptococcus equi subsp. zooepidemicus strain SEZ18
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 128111..138434

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2434_RS00740 (MCPGFBBE_00147)	-	128371..130374 (+)	2004	WP_165623678.1	DUF1430 domain-containing protein	-
I2434_RS00745 (MCPGFBBE_00148)	-	130376..131023 (+)	648	WP_115266548.1	ATP-binding cassette domain-containing protein	-
I2434_RS00750 (MCPGFBBE_00149)	comGA/cglA	131205..132143 (+)	939	WP_115267238.1	competence type IV pilus ATPase ComGA	Machinery gene
I2434_RS00755 (MCPGFBBE_00150)	comYB	132076..133110 (+)	1035	WP_247874574.1	competence type IV pilus assembly protein ComGB	Machinery gene
I2434_RS00760 (MCPGFBBE_00151)	comGC/cglC	133111..133434 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
I2434_RS00765 (MCPGFBBE_00152)	comGD	133412..133837 (+)	426	WP_012514783.1	competence type IV pilus minor pilin ComGD	-
I2434_RS00770	comGE	133794..134084 (+)	291	WP_043030351.1	competence type IV pilus minor pilin ComGE	-
I2434_RS00775 (MCPGFBBE_00153)	comYF	134071..134505 (+)	435	WP_111677651.1	competence type IV pilus minor pilin ComGF	Machinery gene
I2434_RS00780 (MCPGFBBE_00154)	comGG	134483..134845 (+)	363	WP_111677652.1	competence type IV pilus minor pilin ComGG	-
I2434_RS00785	-	134912..136253 (+)	1342	Protein_120	IS3 family transposase	-
I2434_RS00790 (MCPGFBBE_00158)	comYH	136338..137291 (+)	954	WP_012514788.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

Download Length: 107 a.a. Molecular weight: 12149.19 Da Isoelectric Point: 8.4057

                                >NTDB_id=506402 I2434_RS00760 WP_012514782.1 133111..133434(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain SEZ18]

MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE

DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide

Download Length: 324 bp

                                >NTDB_id=506402 I2434_RS00760 WP_012514782.1 133111..133434(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain SEZ18]

ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTATTAAT

CATTAGTGTTTTAATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCAG

TGGTAAAGCTAGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG

GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA

TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-34)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	B4U056

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGC/cglC	Streptococcus mitis SK321	59.813	100	0.598
comGC/cglC	Streptococcus pneumoniae Rx1	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae D39	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae R6	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae TIGR4	57.944	100	0.579
comYC	Streptococcus gordonii str. Challis substr. CH1	62.245	91.589	0.57
comGC/cglC	Streptococcus mitis NCTC 12261	61.616	92.523	0.57
comYC	Streptococcus mutans UA140	58.763	90.654	0.533
comYC	Streptococcus mutans UA159	58.763	90.654	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	56.842	88.785	0.505
comYC	Streptococcus suis isolate S10	60	74.766	0.449
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364

Detailed information NTG0506402