Detailed information NTG0506401

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: I2434_RS00755
• Genome accession: NZ_CP065058
• Coordinates: 132076..133110 (+)
• Length: 344 a.a.
• NCBI ID: WP_247874574.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ18
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 127076..138110

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2434_RS00735	-	128106..128306 (+)	201	WP_165623677.1	lactococcin 972 family bacteriocin	-
I2434_RS00740 (MCPGFBBE_00147)	-	128371..130374 (+)	2004	WP_165623678.1	DUF1430 domain-containing protein	-
I2434_RS00745 (MCPGFBBE_00148)	-	130376..131023 (+)	648	WP_115266548.1	ATP-binding cassette domain-containing protein	-
I2434_RS00750 (MCPGFBBE_00149)	comGA/cglA	131205..132143 (+)	939	WP_115267238.1	competence type IV pilus ATPase ComGA	Machinery gene
I2434_RS00755 (MCPGFBBE_00150)	comYB	132076..133110 (+)	1035	WP_247874574.1	competence type IV pilus assembly protein ComGB	Machinery gene
I2434_RS00760 (MCPGFBBE_00151)	comGC/cglC	133111..133434 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
I2434_RS00765 (MCPGFBBE_00152)	comGD	133412..133837 (+)	426	WP_012514783.1	competence type IV pilus minor pilin ComGD	-
I2434_RS00770	comGE	133794..134084 (+)	291	WP_043030351.1	competence type IV pilus minor pilin ComGE	-
I2434_RS00775 (MCPGFBBE_00153)	comYF	134071..134505 (+)	435	WP_111677651.1	competence type IV pilus minor pilin ComGF	Machinery gene
I2434_RS00780 (MCPGFBBE_00154)	comGG	134483..134845 (+)	363	WP_111677652.1	competence type IV pilus minor pilin ComGG	-
I2434_RS00785	-	134912..136253 (+)	1342	Protein_120	IS3 family transposase	-
I2434_RS00790 (MCPGFBBE_00158)	comYH	136338..137291 (+)	954	WP_012514788.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 344 a.a.
• Molecular weight: 39496.76 Da
• Isoelectric Point: 9.3195

>NTDB_id=506401 I2434_RS00755 WP_247874574.1 132076..133110(+) (comYB) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MISFLQRDISIAGRQGLKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYVTSMEASLLKGNGLVDMLAAL
GYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKRKTIEAVTYPIILLVFLVVIMLGLRHYLIPQLESQNALTDLLL
HLPHYFLGFCLLLLLLIGSFYLYARSCSRLRLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEMMSNEKS
QLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSIMIEYGDIKSKLGQELDIYSQESWETFFSQLNRATQWIQPIIFLV
VAVVIVMIYAAILLPIYQHMGDVF

Nucleotide

• Length: 1035 bp

>NTDB_id=506401 I2434_RS00755 WP_247874574.1 132076..133110(+) (comYB) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
TTGATCAGCTTCTTGCAGAGGGACATCTCAATAGCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAAGCAGCAAGAAAA
GCTTATCCAATTGCTCTATAACCTATTGTCTAACGGCTTTAATTTGACAGAGGTCATTGCTTTTTTGAGAAAAAGCCAGC
TGCTACTGCCAGTCTATGTTACAAGTATGGAAGCAAGCCTATTAAAGGGCAACGGCCTTGTTGACATGCTAGCAGCCTTA
GGTTACTCTGATGCTGTTATGACACAAATTAATCTGGCAGATAAGCATGGCAATATCAAGCTAACCTTGGAAAAAATTCA
GGACTATCTGAGTCAATTTCGCCAAATCAAGCGAAAGACCATCGAGGCAGTCACTTATCCGATCATACTTTTGGTTTTTT
TAGTGGTTATCATGCTAGGCTTGCGGCATTACCTAATCCCTCAGCTAGAGAGTCAAAATGCCTTGACTGACTTGTTGCTT
CATTTGCCTCATTATTTCTTAGGTTTTTGTTTGCTTTTGCTGTTGCTAATTGGCTCTTTTTACCTATATGCCAGATCTTG
TAGTCGGCTAAGGCTATTTAGTCAGCTGAGCTATTATCCTATCATTGGGTCCTTATTGCGGCAATATTTGACAGCCTACT
ATGCTAGAGAATGGGGCAACCTCATCGGACAAGGCTTAGAATTAATCACCATTTTAGAGATGATGTCAAACGAAAAGTCA
CAGCTCATGCGAGAGCTTGCCAAGGATATCAAGCAGAGTCTACTAGCTGGCCAATCCTTTCATCAAAGGGTTGCAGCTTA
TCCCTTTTTTAAAAAGGAGCTAAGCATAATGATTGAATATGGTGACATCAAATCAAAGCTTGGTCAGGAATTAGATATCT
ATTCCCAAGAAAGCTGGGAGACCTTTTTTAGTCAGCTTAATCGGGCAACACAATGGATCCAGCCGATTATTTTTTTAGTG
GTTGCTGTGGTTATTGTGATGATTTATGCTGCTATTTTATTACCAATTTATCAACATATGGGAGATGTTTTTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (29-147)

• Type II secretion system (T2SS), protein F (T2SSF) (215-335)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	53.982	98.547	0.532
comYB	Streptococcus mutans UA159	53.982	98.547	0.532
comYB	Streptococcus gordonii str. Challis substr. CH1	51.765	98.837	0.512
comGB/cglB	Streptococcus mitis NCTC 12261	48.214	97.674	0.471
comGB/cglB	Streptococcus mitis SK321	48.348	96.802	0.468
comGB/cglB	Streptococcus pneumoniae Rx1	47.447	96.802	0.459
comGB/cglB	Streptococcus pneumoniae D39	47.447	96.802	0.459
comGB/cglB	Streptococcus pneumoniae R6	47.447	96.802	0.459
comGB/cglB	Streptococcus pneumoniae TIGR4	47.447	96.802	0.459
comGB	Lactococcus lactis subsp. cremoris KW2	46.018	98.547	0.453