Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   I2434_RS00750 Genome accession   NZ_CP065058
Coordinates   131205..132143 (+) Length   312 a.a.
NCBI ID   WP_115267238.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ18     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 126205..137143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2434_RS00730 (MCPGFBBE_00146) - 126566..127798 (+) 1233 WP_014622136.1 hypothetical protein -
  I2434_RS00735 - 128106..128306 (+) 201 WP_165623677.1 lactococcin 972 family bacteriocin -
  I2434_RS00740 (MCPGFBBE_00147) - 128371..130374 (+) 2004 WP_165623678.1 DUF1430 domain-containing protein -
  I2434_RS00745 (MCPGFBBE_00148) - 130376..131023 (+) 648 WP_115266548.1 ATP-binding cassette domain-containing protein -
  I2434_RS00750 (MCPGFBBE_00149) comGA/cglA 131205..132143 (+) 939 WP_115267238.1 competence type IV pilus ATPase ComGA Machinery gene
  I2434_RS00755 (MCPGFBBE_00150) comYB 132076..133110 (+) 1035 WP_247874574.1 competence type IV pilus assembly protein ComGB Machinery gene
  I2434_RS00760 (MCPGFBBE_00151) comGC/cglC 133111..133434 (+) 324 WP_012514782.1 competence type IV pilus major pilin ComGC Machinery gene
  I2434_RS00765 (MCPGFBBE_00152) comGD 133412..133837 (+) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  I2434_RS00770 comGE 133794..134084 (+) 291 WP_043030351.1 competence type IV pilus minor pilin ComGE -
  I2434_RS00775 (MCPGFBBE_00153) comYF 134071..134505 (+) 435 WP_111677651.1 competence type IV pilus minor pilin ComGF Machinery gene
  I2434_RS00780 (MCPGFBBE_00154) comGG 134483..134845 (+) 363 WP_111677652.1 competence type IV pilus minor pilin ComGG -
  I2434_RS00785 - 134912..136253 (+) 1342 Protein_120 IS3 family transposase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35307.51 Da        Isoelectric Point: 6.8988

>NTDB_id=506400 I2434_RS00750 WP_115267238.1 131205..132143(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MVQELAKRLIRQAEELQAQDIYILPRGASYELLMRIGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGAKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAIVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQANWWNQQIDQLLAEGHLNSRQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=506400 I2434_RS00750 WP_115267238.1 131205..132143(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGGTTCAAGAATTAGCCAAGAGGCTTATCAGGCAGGCCGAAGAATTGCAGGCTCAGGATATTTATATACTGCCAAGAGG
GGCAAGCTATGAGCTTTTGATGAGGATAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCGCTAAGGTATCTCTACGATTATCAGCTGTGGGTGACTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCCAGAGGCCTTT
ACCTCTTTTCTGGACCGGTTGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATTAAAAATGATCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTTTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATAGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAACTGGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATAGCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.71

99.359

0.683
  comYA Streptococcus mutans UA159

63.666

99.679

0.635
  comYA Streptococcus mutans UA140

63.666

99.679

0.635
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.935

99.359

0.615
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.613

99.359

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.613

99.359

0.612
  comGA Lactococcus lactis subsp. cremoris KW2

53.055

99.679

0.529
  comGA Latilactobacillus sakei subsp. sakei 23K

39.931

92.308

0.369