Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SSUD12_RS00770 Genome accession   NC_017621
Coordinates   125225..126175 (+) Length   316 a.a.
NCBI ID   WP_014637312.1    Uniprot ID   -
Organism   Streptococcus suis D12     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 120225..131175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS00760 (SSUD12_0121) - 123789..124154 (+) 366 WP_014637310.1 DUF1033 family protein -
  SSUD12_RS00765 (SSUD12_0122) - 124189..125139 (-) 951 WP_014637311.1 S66 peptidase family protein -
  SSUD12_RS00770 (SSUD12_0123) comYA 125225..126175 (+) 951 WP_014637312.1 competence type IV pilus ATPase ComGA Machinery gene
  SSUD12_RS00775 (SSUD12_0124) comYB 126087..127124 (+) 1038 WP_044669087.1 competence type IV pilus assembly protein ComGB Machinery gene
  SSUD12_RS00780 (SSUD12_0125) comYC 127126..127407 (+) 282 WP_002936550.1 competence type IV pilus major pilin ComGC Machinery gene
  SSUD12_RS00785 (SSUD12_0126) comGD 127388..127795 (+) 408 WP_014637314.1 competence type IV pilus minor pilin ComGD -
  SSUD12_RS00790 (SSUD12_0127) comYE 127767..128060 (+) 294 WP_024410167.1 competence type IV pilus minor pilin ComGE Machinery gene
  SSUD12_RS00795 (SSUD12_0128) comGF/cglF 128047..128481 (+) 435 WP_014637316.1 competence type IV pilus minor pilin ComGF Machinery gene
  SSUD12_RS00800 (SSUD12_0129) comGG 128459..128869 (+) 411 WP_014637317.1 competence type IV pilus minor pilin ComGG -
  SSUD12_RS00805 (SSUD12_0130) comYH 128926..129879 (+) 954 WP_014637318.1 class I SAM-dependent methyltransferase Machinery gene
  SSUD12_RS00810 (SSUD12_0131) - 129929..131116 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35477.26 Da        Isoelectric Point: 5.2978

>NTDB_id=49766 SSUD12_RS00770 WP_014637312.1 125225..126175(+) (comYA) [Streptococcus suis D12]
MIQEKARKLIEEAVADRVSDIYLVPRGQDYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNEQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=49766 SSUD12_RS00770 WP_014637312.1 125225..126175(+) (comYA) [Streptococcus suis D12]
ATGATTCAAGAAAAAGCAAGAAAGTTGATTGAAGAGGCGGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGTGG
TCAGGACTACCAAGTCTACCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGATTAAATGTTGGTGAAAAACGCCGTAGTCAGCAGGGTTCCTGTGATTATGAT
TATGGCAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGTAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTTAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACGCTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACTATCGAGGATCCTGTCGAGATCAAGCAGGAGGATATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGGCCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACGG
CGCGGGCGGTCATCAGGGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGCCCTGAAGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGCTTGATTGG
GGGAGGAGGTGTAGTGGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.595

98.418

0.646
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.484

98.101

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.943

100

0.541
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364

Multiple sequence alignment