Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SSUD12_RS00775 Genome accession   NC_017621
Coordinates   126087..127124 (+) Length   345 a.a.
NCBI ID   WP_044669087.1    Uniprot ID   -
Organism   Streptococcus suis D12     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 121087..132124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS00760 (SSUD12_0121) - 123789..124154 (+) 366 WP_014637310.1 DUF1033 family protein -
  SSUD12_RS00765 (SSUD12_0122) - 124189..125139 (-) 951 WP_014637311.1 S66 peptidase family protein -
  SSUD12_RS00770 (SSUD12_0123) comYA 125225..126175 (+) 951 WP_014637312.1 competence type IV pilus ATPase ComGA Machinery gene
  SSUD12_RS00775 (SSUD12_0124) comYB 126087..127124 (+) 1038 WP_044669087.1 competence type IV pilus assembly protein ComGB Machinery gene
  SSUD12_RS00780 (SSUD12_0125) comYC 127126..127407 (+) 282 WP_002936550.1 competence type IV pilus major pilin ComGC Machinery gene
  SSUD12_RS00785 (SSUD12_0126) comGD 127388..127795 (+) 408 WP_014637314.1 competence type IV pilus minor pilin ComGD -
  SSUD12_RS00790 (SSUD12_0127) comYE 127767..128060 (+) 294 WP_024410167.1 competence type IV pilus minor pilin ComGE Machinery gene
  SSUD12_RS00795 (SSUD12_0128) comGF/cglF 128047..128481 (+) 435 WP_014637316.1 competence type IV pilus minor pilin ComGF Machinery gene
  SSUD12_RS00800 (SSUD12_0129) comGG 128459..128869 (+) 411 WP_014637317.1 competence type IV pilus minor pilin ComGG -
  SSUD12_RS00805 (SSUD12_0130) comYH 128926..129879 (+) 954 WP_014637318.1 class I SAM-dependent methyltransferase Machinery gene
  SSUD12_RS00810 (SSUD12_0131) - 129929..131116 (+) 1188 WP_014637319.1 acetate kinase -
  SSUD12_RS00815 (SSUD12_0132) - 131377..131928 (+) 552 WP_014637320.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38898.83 Da        Isoelectric Point: 9.0934

>NTDB_id=49767 SSUD12_RS00775 WP_044669087.1 126087..127124(+) (comYB) [Streptococcus suis D12]
MNKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSGLSLVVVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=49767 SSUD12_RS00775 WP_044669087.1 126087..127124(+) (comYB) [Streptococcus suis D12]
ATGAACAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAACTGTTTAATAATCTCTTTGCCAGTGGTTTTCATCTGGGAGAGATTGTCGATTTTCTTAAGC
GTAGTCAGCTTTTGGCAGACCCATATACACAAGTTTTATCCGATGGTCTTCTTGCAGGCAAACCTTTTTCAAGTTTGCTG
GCAGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAGGTTCATGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTTAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACTTATCCGATTATATTGC
TTGGTTTTCTGCTTTTGATTATGCTAGGTTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACCGTG
CTGATCAATCATCTACCGACCATCTTTTTATCTCTAAGTGGCCTTAGTTTGGTGGTGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATTAAGGTCTTTTCCTGCTTAGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGTTTGGACCTGCCGCAGATTGTGGGCTTGATGCAAGAG
CAGCAATCGCAGCTTTTTCGTGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTGATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comYB Streptococcus mutans UA140

59.184

99.42

0.588
  comYB Streptococcus mutans UA159

59.184

99.42

0.588
  comGB/cglB Streptococcus mitis NCTC 12261

60.597

97.101

0.588
  comGB/cglB Streptococcus mitis SK321

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae Rx1

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae D39

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae R6

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae TIGR4

60

97.101

0.583
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493

Multiple sequence alignment