Detailed information NTG0049031

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: MSA_RS00405
• Genome accession: NC_021486
• Coordinates: 64103..65011 (+)
• Length: 302 a.a.
• NCBI ID: WP_016480178.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae ILRI005
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 59103..70011

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MSA_RS00380 (MSA_820)	purE	59281..59769 (+)	489	WP_016480172.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
MSA_RS11495 (MSA_840)	purK	59756..60829 (+)	1074	Protein_43	5-(carboxyamino)imidazole ribonucleotide synthase	-
MSA_RS00390 (MSA_850)	-	60839..61096 (+)	258	WP_016480175.1	hypothetical protein	-
MSA_RS00395 (MSA_860)	-	61517..62566 (+)	1050	WP_016480176.1	DUF6287 domain-containing protein	-
MSA_RS00400 (MSA_870)	purB	62652..63950 (+)	1299	WP_016480177.1	adenylosuccinate lyase	-
MSA_RS00405 (MSA_880)	comR	64103..65011 (+)	909	WP_016480178.1	XRE family transcriptional regulator	Regulator
MSA_RS00410 (MSA_890)	ruvB	65210..66208 (+)	999	WP_016480179.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
MSA_RS00415 (MSA_900)	-	66360..66797 (+)	438	WP_016480180.1	low molecular weight protein-tyrosine-phosphatase	-
MSA_RS00420 (MSA_910)	-	66804..67184 (+)	381	WP_000787702.1	membrane protein	-
MSA_RS00425 (MSA_920)	-	67181..68959 (+)	1779	WP_016480181.1	acyltransferase family protein	-

Sequence

Protein

• Length: 302 a.a.
• Molecular weight: 35753.14 Da
• Isoelectric Point: 5.3297

>NTDB_id=49031 MSA_RS00405 WP_016480178.1 64103..65011(+) (comR) [Streptococcus agalactiae ILRI005]
MLKHFGSKVRKFRESQQVTREEFCGDESELSVRQLARIEAGESVPNLSKAHYIARNLGVSLDSLTAGASLELSKKYKELK
YLILRTPTYNDTDRLDLIEKYLDEIYLNFYDDLPEDEKIAIESIQSSLDIYISKSYHFGDDLIREYMNQIKRKKIYSIND
LLIIKLWQYKITASRYDPNIFKIDTFIGTIDKLLNQVKVLSIENLFLLRDVLIYSLGILFILAEYQQIENIINTLNDILI
KTQDFQKRPIIDMFEWKYQLFYKENREVAKRKYQESTLFAQLIGDQVLVTQLKEEWKADYIE

Nucleotide

• Length: 909 bp

>NTDB_id=49031 MSA_RS00405 WP_016480178.1 64103..65011(+) (comR) [Streptococcus agalactiae ILRI005]
ATGTTAAAACATTTTGGTAGTAAAGTAAGGAAGTTTAGGGAATCTCAACAGGTGACACGAGAAGAATTTTGTGGCGATGA
ATCAGAGTTATCGGTCCGACAGCTGGCTCGGATTGAAGCAGGAGAATCTGTTCCAAATTTATCTAAGGCGCATTATATCG
CTAGAAATCTAGGAGTTAGTTTAGATTCCTTAACAGCAGGAGCGAGTTTAGAACTGTCAAAAAAATATAAGGAATTAAAG
TATCTTATATTAAGGACGCCTACCTACAATGATACAGATAGACTTGATTTGATTGAAAAATATCTAGATGAGATTTATTT
AAATTTCTATGATGATTTACCTGAAGATGAAAAAATAGCAATTGAGTCCATACAAAGTTCTTTAGATATTTATATTTCTA
AAAGCTATCATTTTGGAGATGACCTGATTAGAGAATACATGAATCAAATTAAACGAAAAAAGATTTACTCTATCAATGAC
TTACTTATAATTAAACTATGGCAATATAAGATTACTGCTAGCAGGTATGATCCCAATATTTTTAAAATAGATACATTTAT
TGGTACTATAGATAAGTTGCTTAATCAAGTAAAGGTATTATCAATTGAAAACCTGTTTTTATTAAGGGATGTTCTCATTT
ATTCGTTAGGTATATTGTTTATATTAGCTGAATATCAGCAAATAGAAAATATAATAAATACTCTAAATGATATTTTAATA
AAAACTCAGGATTTTCAAAAGAGGCCAATAATAGATATGTTCGAATGGAAATATCAGTTGTTTTATAAAGAAAATAGGGA
AGTGGCTAAAAGAAAATATCAGGAATCAACTCTTTTTGCTCAATTAATCGGCGATCAAGTTTTAGTTACACAGCTAAAAG
AGGAATGGAAAGCAGACTATATAGAATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (74-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	45.151	99.007	0.447
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.296	95.033	0.43
comR	Streptococcus pyogenes MGAS315	43.478	99.007	0.43
comR	Streptococcus pyogenes MGAS8232	41.914	100	0.421
comR	Streptococcus suis P1/7	42.424	98.344	0.417
comR	Streptococcus suis 05ZYH33	42.424	98.344	0.417
comR	Streptococcus suis D9	38.384	98.344	0.377