Detailed information NTG0048935

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SGGB_RS10240
• Genome accession: NC_017576
• Coordinates: 2056821..2058968 (+)
• Length: 715 a.a.
• NCBI ID: WP_013643495.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus ATCC 43143
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2051821..2063968

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGGB_RS10200 (SGGB_2000)	comE/comE1	2051876..2052607 (-)	732	WP_009855001.1	response regulator transcription factor	Regulator
SGGB_RS10205 (SGGB_2001)	-	2052624..2052908 (-)	285	WP_231101259.1	LytTR family DNA-binding domain-containing protein	-
SGGB_RS10210 (SGGB_2002)	-	2053151..2053351 (-)	201	WP_009855003.1	hypothetical protein	-
SGGB_RS10220 (SGGB_2003)	-	2053672..2054685 (-)	1014	WP_009855005.1	bacteriocin biosynthesis protein	-
SGGB_RS10225 (SGGB_2005)	-	2055743..2055940 (-)	198	WP_009855009.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SGGB_RS10230 (SGGB_2006)	-	2055959..2056210 (-)	252	WP_009855010.1	bacteriocin class II family protein	-
SGGB_RS10235 (SGGB_2007)	-	2056457..2056714 (+)	258	WP_009855011.1	hypothetical protein	-
SGGB_RS10240 (SGGB_2008)	comA/nlmT	2056821..2058968 (+)	2148	WP_013643495.1	peptide cleavage/export ABC transporter	Regulator
SGGB_RS10245 (SGGB_2009)	-	2058980..2060374 (+)	1395	WP_013643496.1	bacteriocin secretion accessory protein	-
SGGB_RS10250 (SGGB_2010)	-	2060565..2061239 (+)	675	WP_012962518.1	CPBP family intramembrane glutamic endopeptidase	-
SGGB_RS12015	-	2061257..2061427 (+)	171	WP_012962519.1	hypothetical protein	-
SGGB_RS10255 (SGGB_2011)	-	2061445..2062116 (+)	672	WP_012962520.1	CPBP family intramembrane glutamic endopeptidase	-
SGGB_RS10260 (SGGB_2012)	rsmA	2062150..2063022 (-)	873	WP_012962521.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
SGGB_RS10265 (SGGB_2013)	-	2063092..2063616 (-)	525	WP_012962522.1	DUF1697 domain-containing protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 79904.63 Da
• Isoelectric Point: 6.9233

>NTDB_id=48935 SGGB_RS10240 WP_013643495.1 2056821..2058968(+) (comA/nlmT) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MRRYKYVSQIDLRDCGVAALASVAKHYGSDFSLAHLRELAKTTKEGTTALGIVEAAKAIGFETRAIQANMELFDMADIPY
PFIVHVNKEGKLPHYYVIYKAKKDYLIIGDPDSSVGVTKMSKAHFAKEWTGVAIFLAPAPHYQPHKDKKNGLTSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNHLQSTLGIVSVGLIVTYIMQQIMSFSQNYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNANLFFITLIALPIYAIII
LAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEEVRYQNIDREFVDYLDKSFTLSKYEAVQTSLKQGAQLIL
NVVILWYGSHLVMAGNISVGQLITYNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVSSEFDGKQLLNDSHFLQG
DIVFDDVSYKYGFGRDTLSHVNLHIKKGEKISLVGISGSGKTTLAKMIVNFYTPNHGQITLGGYDLKTIDKKAIRQYINY
LPQQSYVFSGTILENLTLGAPDNITQEEILKACEIAEIRADIESMPLAYHTELSDGAGLSGGQKQRLALARALLTQAPVL
ILDEATSGLDVLTEKRVIKNLLSLTDKTIIFVAHRLSIAEQSDRVIVLDKGQVIEEGYHKQLIQNQGFYAQLFHE

Nucleotide

• Length: 2148 bp

>NTDB_id=48935 SGGB_RS10240 WP_013643495.1 2056821..2058968(+) (comA/nlmT) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGAGAAGATATAAATATGTTAGTCAGATTGATTTGCGAGACTGTGGTGTGGCAGCTTTGGCATCAGTTGCCAAGCATTA
TGGATCAGATTTCTCGCTGGCTCATTTGAGAGAATTAGCCAAAACAACTAAGGAAGGGACAACAGCATTAGGGATAGTTG
AGGCAGCTAAAGCAATCGGCTTTGAAACACGCGCCATTCAGGCTAATATGGAACTGTTTGATATGGCTGATATTCCCTAT
CCTTTTATTGTTCATGTTAACAAAGAAGGCAAACTCCCGCATTACTATGTTATCTACAAAGCCAAAAAAGATTATCTTAT
TATCGGTGACCCTGATTCGAGCGTTGGGGTCACTAAAATGTCCAAAGCGCATTTTGCCAAAGAGTGGACTGGGGTTGCTA
TCTTTTTAGCGCCTGCTCCGCATTATCAACCGCATAAAGATAAGAAAAATGGCTTAACAAGCTTTTTACCAATTATTTTC
AAACAAAAGGCACTGCTAACTTATATCATTCTGGCAAGTTTGCTCGTGACCTTGATTAATATTGTTGGGTCTTACTATTT
GCAAGGAATCTTAGACGATTATATTCCTAATCATTTGCAATCCACTCTTGGCATTGTCTCGGTTGGGTTGATTGTAACCT
ACATAATGCAACAAATCATGAGCTTTTCACAAAATTATTTACTTGTTGTGCTGAGCCAACGGTTAACAATTGACGTGATT
TTGTCTTATATTCGTCATATTTTTGAATTGCCCATGTCCTTTTTTGCCACAAGGCGGACAGGTGAAGTTATCTCACGTTT
CACCGATGCTAACTCGATTATTGATGCACTGGCATCAACGATTCTCTCTTTATTTTTAGATGTGAGTATTTTGTTTATTG
TCGGAAGTGTCTTAATTCTGCAAAATGCCAATCTTTTTTTCATCACCTTAATAGCATTGCCTATCTATGCTATTATTATT
TTGGCTTTTATGAAGCCTTTTGAGCGAATGAATCACGATGTCATGCAAGCCAATTCTATGGTTAGCTCTGCGATTATCGA
AGATATCAATGGTATTGAAACGATTAAATCTTTGACTAGCGAGGAAGTCCGTTATCAAAATATTGACCGTGAATTTGTGG
ATTATTTGGATAAAAGTTTTACGCTTAGTAAGTATGAAGCTGTGCAAACGTCGTTAAAACAGGGAGCACAGCTGATTTTA
AACGTCGTCATTCTCTGGTATGGTTCACATTTAGTCATGGCTGGGAACATTTCAGTAGGTCAATTGATTACTTACAATAC
GCTTCTGTCGTACTTTACAACACCAATGGAAAATATTATTAATCTGCAAACCAAACTACAATCTGCCAAAGTAGCTAACA
ATCGTCTCAACGAAGTTTACTTAGTGTCATCTGAATTTGATGGCAAACAACTCTTAAATGACAGCCATTTTCTACAAGGA
GATATTGTTTTTGATGATGTTTCTTATAAATATGGTTTTGGTCGTGACACACTGAGTCATGTGAATTTACACATTAAGAA
GGGTGAAAAAATTAGCCTAGTTGGTATCAGCGGTTCTGGTAAGACAACCTTAGCTAAAATGATTGTCAATTTTTACACAC
CTAACCATGGACAGATTACCCTTGGTGGCTACGATTTAAAAACCATTGATAAAAAAGCCATTCGCCAATACATTAATTAC
CTACCACAACAGTCTTACGTCTTTTCAGGGACGATTTTAGAAAATTTAACCTTGGGAGCACCTGACAATATCACGCAAGA
AGAAATTCTGAAAGCTTGTGAAATCGCTGAAATCCGTGCTGATATTGAATCGATGCCACTAGCATACCATACCGAACTTT
CAGATGGTGCTGGTTTATCTGGTGGGCAAAAGCAACGTTTAGCTTTAGCACGCGCTTTACTGACACAAGCTCCCGTCTTG
ATTTTAGATGAAGCCACAAGTGGTCTTGATGTTCTAACGGAAAAACGTGTGATTAAAAATTTACTATCTCTCACAGACAA
AACTATTATTTTTGTTGCCCACCGTTTGAGCATTGCTGAACAATCTGACCGTGTCATTGTTCTAGATAAAGGACAAGTTA
TCGAAGAAGGGTATCATAAACAACTCATCCAAAATCAAGGTTTCTATGCACAGTTATTTCATGAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.126	99.72	0.699
comA	Streptococcus mitis NCTC 12261	66.901	99.301	0.664
comA	Streptococcus pneumoniae D39	66.384	99.021	0.657
comA	Streptococcus pneumoniae Rx1	66.384	99.021	0.657
comA	Streptococcus pneumoniae R6	66.384	99.021	0.657
comA	Streptococcus mitis SK321	66.197	99.301	0.657
comA	Streptococcus gordonii str. Challis substr. CH1	65.778	99.72	0.656
comA	Streptococcus pneumoniae TIGR4	66.102	99.021	0.655