Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FOC72_RS09190 Genome accession   NZ_CP054570
Coordinates   1917146..1918087 (-) Length   313 a.a.
NCBI ID   WP_002896773.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1912146..1923087
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS09155 (FOC72_09155) comYH 1913371..1914336 (-) 966 WP_002896764.1 class I SAM-dependent methyltransferase Machinery gene
  FOC72_RS09160 (FOC72_09160) comGG 1914418..1914810 (-) 393 WP_002896765.1 competence type IV pilus minor pilin ComGG -
  FOC72_RS09165 (FOC72_09165) comGF/cglF 1914791..1915228 (-) 438 WP_002896766.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOC72_RS09170 (FOC72_09170) comGE/cglE 1915212..1915445 (-) 234 WP_002896767.1 competence type IV pilus minor pilin ComGE Machinery gene
  FOC72_RS09175 (FOC72_09175) comYD 1915471..1915905 (-) 435 WP_032914279.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOC72_RS09180 (FOC72_09180) comYC 1915865..1916182 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  FOC72_RS09185 (FOC72_09185) comYB 1916182..1917216 (-) 1035 WP_270623281.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOC72_RS09190 (FOC72_09190) comYA 1917146..1918087 (-) 942 WP_002896773.1 competence type IV pilus ATPase ComGA Machinery gene
  FOC72_RS09195 (FOC72_09195) - 1918217..1918597 (-) 381 WP_002896774.1 DUF1033 family protein -
  FOC72_RS09200 (FOC72_09200) - 1918623..1918850 (-) 228 WP_002896775.1 hypothetical protein -
  FOC72_RS09205 (FOC72_09205) - 1919016..1920122 (-) 1107 WP_002896776.1 glycosyl hydrolase family 8 -
  FOC72_RS09210 (FOC72_09210) - 1920131..1921441 (-) 1311 WP_002896777.1 glycosyltransferase -
  FOC72_RS09215 (FOC72_09215) - 1921434..1921577 (-) 144 WP_002896778.1 hypothetical protein -
  FOC72_RS09220 (FOC72_09220) - 1921589..1922377 (-) 789 WP_002896779.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35897.16 Da        Isoelectric Point: 6.1771

>NTDB_id=453522 FOC72_RS09190 WP_002896773.1 1917146..1918087(-) (comYA) [Streptococcus sanguinis strain FDAARGOS_770]
MVQEIAKEMIRQARQEGAQDIYLIPKTTCYELYMRIGDERRFIKTYDFELLSAVISHFKFVAGMNVGEKRRSQLGSCDYD
CEEAKVSIRLSTVGDYRGFESLVIRLLHDEDRELRFWFEQLPELRKKIQARGLYLFSGPVGSGKTTLMYHLAQLKFSGQQ
VMSIEDPVEIKQEAMLQLQLNETIGMTYDSLIKLSLRHRPDLLIIGEIRDRETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELGVSEDELRMVLQGVCYQRLIGGGGVVDFVSQNYQEHEAAVWNQQIDQLFAEGHISAEQRQTEKIVYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=453522 FOC72_RS09190 WP_002896773.1 1917146..1918087(-) (comYA) [Streptococcus sanguinis strain FDAARGOS_770]
ATGGTTCAAGAAATTGCAAAAGAAATGATCAGGCAGGCTCGGCAAGAGGGGGCGCAGGATATTTACCTCATTCCTAAGAC
TACTTGCTATGAGCTTTATATGAGAATCGGTGATGAACGTCGCTTTATAAAAACTTATGATTTCGAGCTTCTGTCAGCTG
TTATCAGCCATTTTAAGTTTGTCGCAGGTATGAATGTTGGAGAGAAGCGCCGCAGTCAGCTTGGGTCTTGCGATTATGAC
TGCGAGGAAGCCAAGGTTTCAATCCGGCTGTCGACAGTTGGGGATTACCGTGGTTTTGAAAGTCTGGTCATCCGACTCCT
GCATGATGAAGACAGGGAGCTGCGCTTCTGGTTTGAGCAATTGCCGGAGCTGCGAAAGAAAATTCAGGCTCGCGGCCTCT
ATCTATTCTCAGGACCAGTCGGCAGTGGCAAGACGACCTTAATGTACCATTTGGCTCAGCTCAAATTTTCTGGTCAGCAG
GTTATGTCGATTGAAGATCCGGTTGAGATTAAGCAAGAGGCTATGCTGCAGCTGCAGCTGAACGAAACCATTGGCATGAC
TTATGACAGTCTAATTAAGCTGTCTCTGCGACATCGGCCGGATCTTTTGATTATCGGGGAAATCCGTGATCGAGAGACAG
CTAGAGCAGTGGTTCGGGCAAGTTTGACCGGAGCTACGGTCTTTTCAACAATTCATGCCAAGAGTGTTCGCGGTGTCTAT
GAGCGGCTTTTGGAATTGGGCGTTAGCGAGGATGAGCTAAGAATGGTGCTGCAAGGTGTTTGTTACCAGCGTTTAATTGG
GGGAGGAGGTGTCGTTGATTTTGTCAGTCAAAACTATCAAGAGCACGAAGCCGCAGTCTGGAATCAGCAGATTGATCAGC
TTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80.645

99.042

0.799
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.08

100

0.751
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.76

100

0.748
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

99.042

0.642
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.007

88.818

0.364