Detailed information NTG0453517

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: FOC72_RS09165
• Genome accession: NZ_CP054570
• Coordinates: 1914791..1915228 (-)
• Length: 145 a.a.
• NCBI ID: WP_002896766.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain FDAARGOS_770
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1909791..1920228

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC72_RS09140 (FOC72_09140)	-	1910492..1911130 (-)	639	WP_002896761.1	CPBP family glutamic-type intramembrane protease	-
FOC72_RS09145 (FOC72_09145)	-	1911248..1911997 (-)	750	WP_002896762.1	CPBP family intramembrane glutamic endopeptidase	-
FOC72_RS09150 (FOC72_09150)	-	1912141..1913334 (-)	1194	WP_002896763.1	acetate kinase	-
FOC72_RS09155 (FOC72_09155)	comYH	1913371..1914336 (-)	966	WP_002896764.1	class I SAM-dependent methyltransferase	Machinery gene
FOC72_RS09160 (FOC72_09160)	comGG	1914418..1914810 (-)	393	WP_002896765.1	competence type IV pilus minor pilin ComGG	-
FOC72_RS09165 (FOC72_09165)	comGF/cglF	1914791..1915228 (-)	438	WP_002896766.1	competence type IV pilus minor pilin ComGF	Machinery gene
FOC72_RS09170 (FOC72_09170)	comGE/cglE	1915212..1915445 (-)	234	WP_002896767.1	competence type IV pilus minor pilin ComGE	Machinery gene
FOC72_RS09175 (FOC72_09175)	comYD	1915471..1915905 (-)	435	WP_032914279.1	competence type IV pilus minor pilin ComGD	Machinery gene
FOC72_RS09180 (FOC72_09180)	comYC	1915865..1916182 (-)	318	WP_002896769.1	competence type IV pilus major pilin ComGC	Machinery gene
FOC72_RS09185 (FOC72_09185)	comYB	1916182..1917216 (-)	1035	WP_270623281.1	competence type IV pilus assembly protein ComGB	Machinery gene
FOC72_RS09190 (FOC72_09190)	comYA	1917146..1918087 (-)	942	WP_002896773.1	competence type IV pilus ATPase ComGA	Machinery gene
FOC72_RS09195 (FOC72_09195)	-	1918217..1918597 (-)	381	WP_002896774.1	DUF1033 family protein	-
FOC72_RS09200 (FOC72_09200)	-	1918623..1918850 (-)	228	WP_002896775.1	hypothetical protein	-
FOC72_RS09205 (FOC72_09205)	-	1919016..1920122 (-)	1107	WP_002896776.1	glycosyl hydrolase family 8	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16799.03 Da
• Isoelectric Point: 5.0577

>NTDB_id=453517 FOC72_RS09165 WP_002896766.1 1914791..1915228(-) (comGF/cglF) [Streptococcus sanguinis strain FDAARGOS_770]
MSKNLKVKAFTLLEALVALLVLSGGVLVFQAMTQLLSSELHQQENNQQQEWFLFADQLETELSRSQFDKVEDNKIYIRQD
GRDLALGKSKGDDFRKTDKSGRGYQPMIYGLEAADVRQDGKLVYLHFRFEKGLEREFVYRVEEES

Nucleotide

• Length: 438 bp

>NTDB_id=453517 FOC72_RS09165 WP_002896766.1 1914791..1915228(-) (comGF/cglF) [Streptococcus sanguinis strain FDAARGOS_770]
GTGTCCAAAAACCTTAAAGTCAAGGCCTTTACTCTCTTGGAGGCTTTAGTAGCCTTGCTGGTTCTCAGTGGCGGTGTGTT
AGTCTTTCAGGCCATGACCCAGCTCTTATCTTCAGAACTGCATCAGCAGGAAAACAATCAGCAGCAAGAGTGGTTTTTGT
TTGCCGACCAACTGGAGACGGAGCTTTCGCGAAGTCAATTTGATAAGGTTGAAGACAACAAAATCTACATCAGACAGGAT
GGCAGGGACTTGGCCTTGGGTAAATCTAAGGGCGATGATTTCCGTAAAACAGATAAGAGCGGTCGCGGCTACCAGCCGAT
GATTTATGGTTTAGAAGCAGCTGACGTCCGTCAGGACGGTAAGCTTGTCTATCTTCATTTTCGCTTTGAAAAAGGCTTAG
AGAGGGAGTTCGTCTATCGTGTGGAAGAAGAAAGTTGA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	64.336	98.621	0.634
comGF/cglF	Streptococcus pneumoniae D39	64.336	98.621	0.634
comGF/cglF	Streptococcus pneumoniae R6	64.336	98.621	0.634
comGF/cglF	Streptococcus pneumoniae TIGR4	64.336	98.621	0.634
comGF/cglF	Streptococcus mitis SK321	62.937	98.621	0.621
comGF/cglF	Streptococcus mitis NCTC 12261	61.538	98.621	0.607
comYF	Streptococcus mutans UA159	47.143	96.552	0.455
comYF	Streptococcus mutans UA140	46.429	96.552	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	41.912	93.793	0.393