Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   I6H74_RS01315 Genome accession   NZ_CP066069
Coordinates   249075..249986 (-) Length   303 a.a.
NCBI ID   WP_115256701.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 244075..254986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS01290 (I6H74_01290) - 245075..246850 (-) 1776 WP_003059359.1 acyltransferase family protein -
  I6H74_RS01295 (I6H74_01295) - 246847..247248 (-) 402 WP_003049089.1 MORN repeat-containing protein -
  I6H74_RS01300 (I6H74_01300) - 247277..247708 (-) 432 WP_003059365.1 low molecular weight protein-tyrosine-phosphatase -
  I6H74_RS01305 (I6H74_01305) ruvB 247843..248841 (-) 999 WP_015057190.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  I6H74_RS01310 comS 248893..248988 (-) 96 WP_198455558.1 quorum-sensing system DWW-type pheromone Regulator
  I6H74_RS01315 (I6H74_01310) comR 249075..249986 (-) 912 WP_115256701.1 XRE family transcriptional regulator Regulator
  I6H74_RS01320 (I6H74_01315) purB 250128..251420 (-) 1293 WP_022554088.1 adenylosuccinate lyase -
  I6H74_RS01325 (I6H74_01320) - 251605..253464 (-) 1860 WP_015016520.1 DUF262 domain-containing protein -
  I6H74_RS01330 (I6H74_01325) purK 253483..254556 (-) 1074 WP_115256700.1 5-(carboxyamino)imidazole ribonucleotide synthase -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35712.29 Da        Isoelectric Point: 4.5798

>NTDB_id=453519 I6H74_RS01315 WP_115256701.1 249075..249986(-) (comR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEQLIIECLQATLDTLLSENINFGVELLQEYFKQTKVKLRFKQND
LILIELYLAYLDIEGMYGEYSDKVFYDSLLDNLLKQFDDFELDELFIVNKVIIDISSLSIKTNKLDNLEKTIAISQKIMA
KIQDWNRMPILKLIEWKYFLIKQKNRKQAEESYTKACLFAQITGDKYLEEQLIKEWEKDICAY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=453519 I6H74_RS01315 WP_115256701.1 249075..249986(-) (comR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGTGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAACAATTGATTATAGAATGTTTACAGGCTACGCTAGACACTTTATTAAGTG
AAAACATCAATTTTGGTGTCGAATTATTGCAGGAATATTTTAAACAAACCAAAGTTAAACTACGTTTTAAACAAAACGAC
TTGATACTTATTGAACTCTATCTGGCTTATCTCGATATTGAAGGGATGTATGGAGAATATTCTGATAAGGTTTTTTATGA
TTCTTTGTTAGATAACCTGTTAAAACAATTCGATGACTTTGAATTAGACGAACTGTTCATAGTTAATAAAGTTATTATTG
ATATTTCTTCTTTAAGTATTAAAACTAATAAACTAGATAATCTAGAAAAGACGATTGCTATAAGTCAAAAAATCATGGCA
AAAATCCAGGATTGGAATAGAATGCCTATACTAAAATTAATAGAATGGAAGTACTTTTTAATAAAACAAAAGAACAGAAA
ACAAGCAGAGGAATCATATACAAAGGCGTGTCTGTTTGCGCAAATAACAGGAGACAAGTATTTGGAAGAGCAATTAATCA
AAGAATGGGAGAAAGATATTTGTGCTTATTAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(12-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

81.848

100

0.818
  comR Streptococcus pyogenes MGAS315

54.333

99.01

0.538
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

51.186

97.36

0.498
  comR Streptococcus mutans UA159

49.833

98.68

0.492