Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   FOC72_RS09155 Genome accession   NZ_CP054570
Coordinates   1913371..1914336 (-) Length   321 a.a.
NCBI ID   WP_002896764.1    Uniprot ID   A0A859ERG8
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1908371..1919336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS09135 (FOC72_09135) folP 1909344..1910297 (-) 954 WP_002896760.1 dihydropteroate synthase -
  FOC72_RS09140 (FOC72_09140) - 1910492..1911130 (-) 639 WP_002896761.1 CPBP family glutamic-type intramembrane protease -
  FOC72_RS09145 (FOC72_09145) - 1911248..1911997 (-) 750 WP_002896762.1 CPBP family intramembrane glutamic endopeptidase -
  FOC72_RS09150 (FOC72_09150) - 1912141..1913334 (-) 1194 WP_002896763.1 acetate kinase -
  FOC72_RS09155 (FOC72_09155) comYH 1913371..1914336 (-) 966 WP_002896764.1 class I SAM-dependent methyltransferase Machinery gene
  FOC72_RS09160 (FOC72_09160) comGG 1914418..1914810 (-) 393 WP_002896765.1 competence type IV pilus minor pilin ComGG -
  FOC72_RS09165 (FOC72_09165) comGF/cglF 1914791..1915228 (-) 438 WP_002896766.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOC72_RS09170 (FOC72_09170) comGE/cglE 1915212..1915445 (-) 234 WP_002896767.1 competence type IV pilus minor pilin ComGE Machinery gene
  FOC72_RS09175 (FOC72_09175) comYD 1915471..1915905 (-) 435 WP_032914279.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOC72_RS09180 (FOC72_09180) comYC 1915865..1916182 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  FOC72_RS09185 (FOC72_09185) comYB 1916182..1917216 (-) 1035 WP_270623281.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOC72_RS09190 (FOC72_09190) comYA 1917146..1918087 (-) 942 WP_002896773.1 competence type IV pilus ATPase ComGA Machinery gene
  FOC72_RS09195 (FOC72_09195) - 1918217..1918597 (-) 381 WP_002896774.1 DUF1033 family protein -
  FOC72_RS09200 (FOC72_09200) - 1918623..1918850 (-) 228 WP_002896775.1 hypothetical protein -

Sequence

Protein


Download         Length: 321 a.a.        Molecular weight: 36666.67 Da        Isoelectric Point: 4.6825

>NTDB_id=453516 FOC72_RS09155 WP_002896764.1 1913371..1914336(-) (comYH) [Streptococcus sanguinis strain FDAARGOS_770]
MNFEKIEQAYTLILENVQNIQNALATNFYDALIEHNGIYLDGDTDLQEVLANDEKIRALHLTKEEWRRAYQFILMKAAQT
EPMQVNHQFTPDTIGFLITFLLDQLAHGEEADVLEIGSGTGNLAETILNHTQKKIDYLGLELDDLLIDLSASIAEVMNSK
AHFAQGDAVRPQVLKESDIIISDLPVGYYPDDSIASRYEVASPDEHTYAHHLLMEQSLKYLKPGGYAIFLAPNDLLTSAQ
APLLKKWLLAKAQFIAMITLPESIFSSSKHAKTLFVLRKQEANNIQPFIYPLRDLQDHEEMFKFRQSFQNWYKDSEIQTK
F

Nucleotide


Download         Length: 966 bp        

>NTDB_id=453516 FOC72_RS09155 WP_002896764.1 1913371..1914336(-) (comYH) [Streptococcus sanguinis strain FDAARGOS_770]
ATGAATTTTGAAAAGATAGAACAAGCTTATACTCTGATTCTCGAAAACGTCCAGAATATCCAAAACGCTCTGGCGACCAA
TTTTTACGATGCTCTGATTGAGCATAACGGCATTTACCTAGATGGAGATACGGACTTACAAGAAGTTCTGGCCAACGATG
AAAAAATCCGCGCTCTGCATTTGACCAAGGAAGAGTGGCGGAGAGCCTATCAGTTTATCCTGATGAAGGCGGCCCAGACG
GAGCCCATGCAGGTCAATCATCAATTCACACCTGACACAATTGGTTTTCTGATTACTTTCTTATTGGACCAGCTAGCTCA
CGGAGAGGAAGCTGATGTATTAGAAATTGGCAGTGGGACTGGAAATTTGGCTGAGACTATTCTTAATCATACCCAAAAGA
AAATAGATTACCTAGGTCTGGAGCTAGATGATTTATTAATTGACCTTTCTGCCAGCATTGCAGAGGTTATGAACTCTAAG
GCTCACTTTGCTCAGGGTGATGCGGTTCGGCCTCAGGTTCTGAAAGAGAGTGACATCATTATCAGTGATTTACCGGTCGG
TTATTATCCGGATGACAGTATCGCCTCTCGCTATGAAGTGGCTAGTCCGGATGAGCACACTTATGCCCACCATCTTCTAA
TGGAACAGTCGCTCAAATATCTTAAACCGGGAGGCTATGCCATATTTCTGGCGCCGAATGACCTCTTGACCAGCGCTCAA
GCTCCTCTGCTGAAAAAATGGCTCCTAGCCAAAGCACAGTTCATCGCGATGATAACCTTGCCAGAGTCTATTTTCTCAAG
CAGCAAGCATGCCAAAACTCTTTTTGTCTTGAGGAAACAGGAAGCGAATAATATTCAGCCTTTTATCTATCCTCTGCGGG
ATTTGCAGGACCATGAAGAAATGTTTAAATTCCGTCAAAGTTTTCAAAACTGGTACAAAGATAGTGAAATTCAAACAAAA
TTTTGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A859ERG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

58.73

98.131

0.576
  comYH Streptococcus mutans UA140

58.413

98.131

0.573