Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FOC72_RS09185 Genome accession   NZ_CP054570
Coordinates   1916182..1917216 (-) Length   344 a.a.
NCBI ID   WP_270623281.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1911182..1922216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS09145 (FOC72_09145) - 1911248..1911997 (-) 750 WP_002896762.1 CPBP family intramembrane glutamic endopeptidase -
  FOC72_RS09150 (FOC72_09150) - 1912141..1913334 (-) 1194 WP_002896763.1 acetate kinase -
  FOC72_RS09155 (FOC72_09155) comYH 1913371..1914336 (-) 966 WP_002896764.1 class I SAM-dependent methyltransferase Machinery gene
  FOC72_RS09160 (FOC72_09160) comGG 1914418..1914810 (-) 393 WP_002896765.1 competence type IV pilus minor pilin ComGG -
  FOC72_RS09165 (FOC72_09165) comGF/cglF 1914791..1915228 (-) 438 WP_002896766.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOC72_RS09170 (FOC72_09170) comGE/cglE 1915212..1915445 (-) 234 WP_002896767.1 competence type IV pilus minor pilin ComGE Machinery gene
  FOC72_RS09175 (FOC72_09175) comYD 1915471..1915905 (-) 435 WP_032914279.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOC72_RS09180 (FOC72_09180) comYC 1915865..1916182 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  FOC72_RS09185 (FOC72_09185) comYB 1916182..1917216 (-) 1035 WP_270623281.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOC72_RS09190 (FOC72_09190) comYA 1917146..1918087 (-) 942 WP_002896773.1 competence type IV pilus ATPase ComGA Machinery gene
  FOC72_RS09195 (FOC72_09195) - 1918217..1918597 (-) 381 WP_002896774.1 DUF1033 family protein -
  FOC72_RS09200 (FOC72_09200) - 1918623..1918850 (-) 228 WP_002896775.1 hypothetical protein -
  FOC72_RS09205 (FOC72_09205) - 1919016..1920122 (-) 1107 WP_002896776.1 glycosyl hydrolase family 8 -
  FOC72_RS09210 (FOC72_09210) - 1920131..1921441 (-) 1311 WP_002896777.1 glycosyltransferase -
  FOC72_RS09215 (FOC72_09215) - 1921434..1921577 (-) 144 WP_002896778.1 hypothetical protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39010.84 Da        Isoelectric Point: 8.2406

>NTDB_id=453521 FOC72_RS09185 WP_270623281.1 1916182..1917216(-) (comYB) [Streptococcus sanguinis strain FDAARGOS_770]
MISFLQKDISVLSKGRPKKLSTPKQKKIIELFHNLFSSGFHLAEIVDFLRRSALLEEVYVAEMQAGLSAGQSFSEIVSRL
GFSDSVVTQLSLSELHGNLTLSLGKIETYLENLSKVKKKLIEVGTYPLMLLGFLVLIMLGLRNYLLPQLDSQNLATQLIN
HLPQIFLWSSLAWAALVSVALFYYRKSSKIRFFSKLAALPFFGHLVQAYLTAYYAREWGNMIGQGLELSQIFAIMQEQPS
QLFQEIGEDMAAALQGGQGYADKVASYPFFKKELSLMIEYGEVKSKLGSELEVYAEKTWEEFFLRINRAMNFIQPLVFIF
VALVIVLLYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=453521 FOC72_RS09185 WP_270623281.1 1916182..1917216(-) (comYB) [Streptococcus sanguinis strain FDAARGOS_770]
TTGATCAGCTTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAAGCAGAAAAA
GATTATTGAGCTCTTTCATAATCTCTTTAGCAGCGGTTTTCACTTAGCAGAGATTGTAGACTTTCTGAGGCGAAGTGCCT
TGCTGGAGGAAGTGTATGTCGCAGAAATGCAGGCAGGCTTGTCAGCTGGTCAATCCTTTTCAGAGATTGTCAGTCGACTG
GGATTTTCCGACAGCGTTGTAACCCAGCTGTCCTTATCTGAGCTACATGGCAATCTGACACTTAGTCTGGGCAAGATTGA
GACCTATCTGGAAAATCTGTCCAAGGTTAAGAAAAAATTGATAGAGGTAGGAACCTATCCTCTCATGCTGCTGGGCTTTT
TGGTCCTTATCATGCTGGGATTGCGCAACTATCTTCTGCCTCAATTAGACAGCCAGAATCTAGCTACTCAGCTGATTAAT
CACCTGCCTCAGATTTTTTTGTGGAGCAGCCTTGCTTGGGCCGCCTTGGTTTCAGTGGCTCTCTTTTATTATCGAAAGTC
ATCCAAGATTCGTTTTTTCAGCAAACTAGCAGCTCTGCCCTTTTTTGGACATTTGGTACAGGCTTACTTGACCGCTTATT
ATGCTCGTGAATGGGGAAATATGATTGGCCAGGGCTTGGAACTGAGTCAGATTTTTGCGATTATGCAGGAGCAGCCTTCC
CAGCTCTTTCAGGAAATAGGAGAAGATATGGCTGCTGCTTTGCAAGGCGGTCAAGGCTATGCGGACAAGGTGGCGAGCTA
TCCTTTCTTTAAGAAAGAATTGTCCCTGATGATCGAGTATGGTGAGGTCAAGTCCAAGCTGGGGAGTGAACTGGAAGTCT
ATGCTGAAAAGACTTGGGAGGAATTTTTCCTACGTATCAACCGGGCCATGAATTTCATTCAGCCCCTAGTATTTATTTTT
GTTGCCTTAGTGATTGTTTTACTTTATGCGGCAATGCTCTTGCCCATTTATCAGAATATGGAGGTTCATTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(29-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.547

100

0.735
  comGB/cglB Streptococcus mitis NCTC 12261

69.94

97.674

0.683
  comGB/cglB Streptococcus mitis SK321

68.75

97.674

0.672
  comGB/cglB Streptococcus pneumoniae TIGR4

67.857

97.674

0.663
  comGB/cglB Streptococcus pneumoniae R6

67.857

97.674

0.663
  comGB/cglB Streptococcus pneumoniae Rx1

67.857

97.674

0.663
  comGB/cglB Streptococcus pneumoniae D39

67.857

97.674

0.663
  comYB Streptococcus mutans UA140

60.641

99.709

0.605
  comYB Streptococcus mutans UA159

60.641

99.709

0.605
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.965

0.497