Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   HBA50_RS00875 Genome accession   NZ_CP050133
Coordinates   169033..169350 (+) Length   105 a.a.
NCBI ID   WP_045500288.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 164033..174350
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS00845 (HBA50_00845) comW 164801..165028 (+) 228 WP_045500276.1 sigma(X)-activator ComW -
  HBA50_RS00855 (HBA50_00855) - 165271..166539 (+) 1269 WP_045500279.1 CapA family protein -
  HBA50_RS00860 (HBA50_00860) - 166674..167045 (+) 372 WP_045500282.1 DUF1033 family protein -
  HBA50_RS00865 (HBA50_00865) comYA 167131..168072 (+) 942 WP_045500284.1 competence type IV pilus ATPase ComGA Machinery gene
  HBA50_RS00870 (HBA50_00870) comYB 168020..169036 (+) 1017 WP_045500287.1 competence type IV pilus assembly protein ComGB Machinery gene
  HBA50_RS00875 (HBA50_00875) comYC 169033..169350 (+) 318 WP_045500288.1 competence type IV pilus major pilin ComGC Machinery gene
  HBA50_RS00880 (HBA50_00880) comYD 169310..169744 (+) 435 WP_045500291.1 competence type IV pilus minor pilin ComGD Machinery gene
  HBA50_RS00885 (HBA50_00885) comGE 169710..170003 (+) 294 WP_200893262.1 competence type IV pilus minor pilin ComGE -
  HBA50_RS00890 (HBA50_00890) comGF/cglF 169987..170424 (+) 438 WP_045500297.1 competence type IV pilus minor pilin ComGF Machinery gene
  HBA50_RS00895 (HBA50_00895) comGG 170405..170803 (+) 399 WP_045500299.1 competence type IV pilus minor pilin ComGG -
  HBA50_RS00900 (HBA50_00900) comYH 170884..171849 (+) 966 WP_045500301.1 class I SAM-dependent methyltransferase Machinery gene
  HBA50_RS00905 (HBA50_00905) - 171885..173078 (+) 1194 WP_045500304.1 acetate kinase -
  HBA50_RS00910 (HBA50_00910) - 173389..174279 (-) 891 WP_045500311.1 RluA family pseudouridine synthase -

Sequence


Protein


Download         Length: 105 a.a.        Molecular weight: 11572.66 Da        Isoelectric Point: 10.0731

>NTDB_id=430187 HBA50_RS00875 WP_045500288.1 169033..169350(+) (comYC) [Streptococcus cristatus ATCC 51100]
MKKLKTLKVKAFTLVEMLVVLLIISVLMLLFVPNLTRQKDTVSDTGNAAVVKVVESQAELYELKNVNEKATLGKLVADGR
ITDKQVASYKAYYGKNSSEPRAVAD

Nucleotide


Download         Length: 318 bp        

>NTDB_id=430187 HBA50_RS00875 WP_045500288.1 169033..169350(+) (comYC) [Streptococcus cristatus ATCC 51100]
ATGAAAAAATTAAAAACTTTGAAGGTTAAAGCTTTCACTCTGGTGGAAATGTTAGTCGTTCTTTTAATCATCAGCGTCTT
GATGCTCTTGTTTGTTCCGAATTTGACTAGGCAGAAGGATACTGTTTCAGATACGGGCAATGCGGCCGTAGTCAAGGTGG
TAGAAAGTCAGGCTGAGCTTTATGAATTGAAGAATGTTAATGAAAAAGCCACTCTAGGGAAATTGGTTGCTGATGGTCGG
ATTACCGATAAGCAGGTAGCATCCTATAAGGCTTACTATGGAAAAAACAGCAGTGAACCTCGTGCAGTTGCGGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

80

100

0.8

  comYC Streptococcus mutans UA140

68.571

100

0.686

  comYC Streptococcus mutans UA159

68.571

100

0.686

  comGC/cglC Streptococcus pneumoniae R6

69.608

97.143

0.676

  comGC/cglC Streptococcus pneumoniae TIGR4

69.608

97.143

0.676

  comGC/cglC Streptococcus mitis SK321

69.608

97.143

0.676

  comGC/cglC Streptococcus pneumoniae Rx1

69.608

97.143

0.676

  comGC/cglC Streptococcus pneumoniae D39

69.608

97.143

0.676

  comGC/cglC Streptococcus mitis NCTC 12261

68.627

97.143

0.667

  comGC Lactococcus lactis subsp. cremoris KW2

57.692

99.048

0.571

  comYC Streptococcus suis isolate S10

65.169

84.762

0.552