Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   HBA50_RS00870 Genome accession   NZ_CP050133
Coordinates   168020..169036 (+) Length   338 a.a.
NCBI ID   WP_045500287.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 163020..174036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS00840 (HBA50_00840) wecB 163560..164648 (+) 1089 WP_045500273.1 non-hydrolyzing UDP-N-acetylglucosamine 2-epimerase -
  HBA50_RS00845 (HBA50_00845) comW 164801..165028 (+) 228 WP_045500276.1 sigma(X)-activator ComW -
  HBA50_RS00855 (HBA50_00855) - 165271..166539 (+) 1269 WP_045500279.1 CapA family protein -
  HBA50_RS00860 (HBA50_00860) - 166674..167045 (+) 372 WP_045500282.1 DUF1033 family protein -
  HBA50_RS00865 (HBA50_00865) comYA 167131..168072 (+) 942 WP_045500284.1 competence type IV pilus ATPase ComGA Machinery gene
  HBA50_RS00870 (HBA50_00870) comYB 168020..169036 (+) 1017 WP_045500287.1 competence type IV pilus assembly protein ComGB Machinery gene
  HBA50_RS00875 (HBA50_00875) comYC 169033..169350 (+) 318 WP_045500288.1 competence type IV pilus major pilin ComGC Machinery gene
  HBA50_RS00880 (HBA50_00880) comYD 169310..169744 (+) 435 WP_045500291.1 competence type IV pilus minor pilin ComGD Machinery gene
  HBA50_RS00885 (HBA50_00885) comGE 169710..170003 (+) 294 WP_200893262.1 competence type IV pilus minor pilin ComGE -
  HBA50_RS00890 (HBA50_00890) comGF/cglF 169987..170424 (+) 438 WP_045500297.1 competence type IV pilus minor pilin ComGF Machinery gene
  HBA50_RS00895 (HBA50_00895) comGG 170405..170803 (+) 399 WP_045500299.1 competence type IV pilus minor pilin ComGG -
  HBA50_RS00900 (HBA50_00900) comYH 170884..171849 (+) 966 WP_045500301.1 class I SAM-dependent methyltransferase Machinery gene
  HBA50_RS00905 (HBA50_00905) - 171885..173078 (+) 1194 WP_045500304.1 acetate kinase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38740.75 Da        Isoelectric Point: 9.4196

>NTDB_id=430186 HBA50_RS00870 WP_045500287.1 168020..169036(+) (comYB) [Streptococcus cristatus ATCC 51100]
MDISQLIKGRRKKLSTPKQKKIIELFRNLFTSGFHLAEIVDFLRRSALLEEVYVAEMRSGLAAGQSFSQIMKRLGFSDNV
VTQLSLSELHGNLNLSLGKIEDYLENLSKVRKKLIEVGTYPLMLLGFLVLIMLGLRNYLLPQLDSQNMATQFIHHLPQIF
LGGVLVNCLLICGGWFYFRKSSKMRFFSRLAKFPFVGTLVRAYLTAYYAREWGNMIGQGLELSQIFLIMQDQPSQLFQEL
GRDLETALGAGQGYAEKVGTYPFFKKELALIIEYGEVKSKLGDELELYAEKTWEEFFLRINRAMNLIQPLVFVFVALVIV
LLYAAMLLPIYQNMEIQL

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=430186 HBA50_RS00870 WP_045500287.1 168020..169036(+) (comYB) [Streptococcus cristatus ATCC 51100]
ATGGACATATCACAGCTGATCAAAGGCAGGCGGAAAAAATTATCTACGCCTAAGCAAAAGAAGATTATCGAGCTGTTCCG
CAATCTCTTTACCAGCGGTTTTCATCTGGCAGAGATTGTCGATTTTCTACGGCGGAGTGCCCTTTTAGAAGAGGTCTATG
TCGCAGAAATGCGTTCGGGTTTGGCTGCCGGCCAGTCGTTTTCCCAGATTATGAAGCGTTTGGGCTTTTCAGATAATGTG
GTCACCCAGCTATCTTTGTCAGAGTTGCATGGAAATCTAAATCTGAGTTTGGGTAAAATCGAGGATTATCTGGAAAATCT
ATCCAAGGTTCGTAAGAAATTGATTGAGGTGGGGACTTATCCCTTGATGCTGCTTGGGTTTTTGGTGCTGATTATGCTAG
GCTTGCGTAATTATCTCTTGCCCCAGCTGGATAGTCAAAATATGGCTACTCAGTTCATTCATCACCTACCGCAAATCTTC
TTGGGAGGCGTTCTGGTGAATTGCTTGCTGATTTGCGGTGGCTGGTTCTATTTTCGCAAGAGCTCTAAGATGAGATTTTT
CAGTCGTTTGGCCAAGTTTCCTTTTGTTGGCACCCTAGTACGAGCCTATCTGACGGCCTACTATGCGCGTGAATGGGGAA
ATATGATTGGGCAAGGGCTGGAATTAAGCCAGATCTTTCTCATCATGCAGGACCAGCCTTCTCAGCTCTTTCAGGAGCTG
GGACGAGACTTGGAGACGGCTCTAGGTGCAGGTCAGGGCTATGCCGAGAAGGTCGGTACCTACCCCTTCTTTAAGAAAGA
GCTGGCCTTAATCATCGAATACGGCGAGGTCAAGTCCAAGTTGGGTGACGAATTGGAACTGTATGCCGAAAAGACTTGGG
AAGAGTTTTTCCTGAGAATCAATCGTGCCATGAATTTGATTCAGCCTCTCGTCTTTGTCTTTGTCGCCCTCGTGATCGTT
TTACTTTATGCAGCTATGTTGCTGCCAATTTATCAGAATATGGAGATTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

71.513

99.704

0.713
  comGB/cglB Streptococcus mitis NCTC 12261

67.857

99.408

0.675
  comGB/cglB Streptococcus mitis SK321

67.56

99.408

0.672
  comGB/cglB Streptococcus pneumoniae TIGR4

67.262

99.408

0.669
  comGB/cglB Streptococcus pneumoniae R6

67.262

99.408

0.669
  comGB/cglB Streptococcus pneumoniae Rx1

67.262

99.408

0.669
  comGB/cglB Streptococcus pneumoniae D39

67.262

99.408

0.669
  comYB Streptococcus mutans UA140

60.252

93.787

0.565
  comYB Streptococcus mutans UA159

59.937

93.787

0.562
  comGB Lactococcus lactis subsp. cremoris KW2

50.599

98.817

0.5