Detailed information NTG0418233

Bioinformatically predicted

Overview

• Name: comX/sigX/comX1/sigX1
• Type: Regulator
• Locus tag: M594_RS01030
• Genome accession: NZ_CP047883
• Coordinates: 204071..204550 (+)
• Length: 159 a.a.
• NCBI ID: WP_173875742.1
• Uniprot ID: A0A6M9F9W4
• Organism: Streptococcus mitis strain S022-V3-A4
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 199071..209550

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M594_RS01005 (M594_01025)	-	199812..200687 (-)	876	WP_302478532.1	RluA family pseudouridine synthase	-
M594_RS01010 (M594_01030)	pbp2a	200774..202969 (+)	2196	WP_173875741.1	penicillin-binding protein PBP2A	-
M594_RS01015 (M594_01035)	rpmG	203022..203174 (+)	153	WP_001809375.1	50S ribosomal protein L33	-
M594_RS01020 (M594_01040)	secE	203184..203360 (+)	177	WP_042900249.1	preprotein translocase subunit SecE	-
M594_RS01025 (M594_01045)	nusG	203414..203950 (+)	537	WP_049499248.1	transcription termination/antitermination protein NusG	-
M594_RS01030 (M594_01050)	comX/sigX/comX1/sigX1	204071..204550 (+)	480	WP_173875742.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 20090.82 Da
• Isoelectric Point: 8.6707

>NTDB_id=418233 M594_RS01030 WP_173875742.1 204071..204550(+) (comX/sigX/comX1/sigX1) [Streptococcus mitis strain S022-V3-A4]
MFKELYKEVQGIVYKSRNEYYLHLWELSDWDQEGMICLHELISREEELVEDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDEYYLFHETLRDYRNKQSKDKQEELERVLRNERFRGRQRVLRDLRIVFKEFDIRTR

Nucleotide

• Length: 480 bp

>NTDB_id=418233 M594_RS01030 WP_173875742.1 204071..204550(+) (comX/sigX/comX1/sigX1) [Streptococcus mitis strain S022-V3-A4]
ATGTTTAAAGAATTGTATAAAGAAGTCCAGGGAATTGTATATAAAAGTAGAAATGAATATTACCTTCATTTATGGGAGCT
ATCGGATTGGGACCAAGAGGGAATGATTTGCTTACATGAATTGATCAGTAGAGAAGAAGAGCTAGTAGAAGATATTCCTC
GTTTAAGGAAATATTTTAAGACTAAGTTCCGGAATCGAATTCTAGACTATATCCGTAAGCAAGAAAGTCAGAAGCGTAGA
TATGATAAAGAACCCTATGAAGAAGTAGGTGAGATTAGTCATCGTATAAGCGAGGGAGGTCTGTGGCTAGATGAGTATTA
TCTCTTTCATGAGACACTAAGAGATTATAGAAACAAACAAAGTAAAGACAAACAAGAAGAGTTAGAACGCGTCTTAAGAA
ATGAACGCTTCCGAGGGCGTCAAAGAGTATTAAGGGACTTACGTATTGTGTTTAAGGAATTTGATATCCGTACTCGGTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A6M9F9W4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	96.226	100	0.962
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	96.226	100	0.962
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	96.835	99.371	0.962
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	95.57	99.371	0.95
comX/comX2	Streptococcus pneumoniae R6	93.038	99.371	0.925
comX/comX1	Streptococcus pneumoniae R6	93.038	99.371	0.925
comX/comX2	Streptococcus pneumoniae D39	93.038	99.371	0.925
comX/comX2	Streptococcus pneumoniae Rx1	93.038	99.371	0.925
comX/comX1	Streptococcus pneumoniae Rx1	93.038	99.371	0.925
comX/comX1	Streptococcus pneumoniae D39	93.038	99.371	0.925
comX/comX2	Streptococcus pneumoniae TIGR4	92.405	99.371	0.918
comX/comX1	Streptococcus pneumoniae TIGR4	92.405	99.371	0.918
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	50	98.113	0.491
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	50	98.113	0.491
comX/sigX	Streptococcus mutans UA159	47.059	96.226	0.453
comX/sigX	Streptococcus suis isolate S10	46.405	96.226	0.447
comX/sigX	Streptococcus suis D9	46.405	96.226	0.447
comX/sigX	Streptococcus suis P1/7	46.405	96.226	0.447
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.282	93.711	0.396
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.282	93.711	0.396
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.282	93.711	0.396
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.282	93.711	0.396
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	41.447	95.597	0.396
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	41.447	95.597	0.396
comX	Streptococcus salivarius SK126	37.419	97.484	0.365