Detailed information NTG0409090

Bioinformatically predicted

Overview

• Name: comX/sigX
• Type: Regulator
• Locus tag: GP482_RS00160
• Genome accession: NZ_CP046875
• Coordinates: 27177..27653 (+)
• Length: 158 a.a.
• NCBI ID: WP_039696070.1
• Uniprot ID: A0A091BY39
• Organism: Streptococcus ruminicola strain CNU_77-61
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 22177..32653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GP482_RS00160 (GP482_00160)	comX/sigX	27177..27653 (+)	477	WP_039696070.1	sigma-70 family RNA polymerase sigma factor	Regulator
GP482_RS00165 (GP482_00165)	-	27849..28115 (+)	267	WP_039696002.1	ACT domain-containing protein	-
GP482_RS00170 (GP482_00170)	-	28127..29464 (+)	1338	WP_158913156.1	PFL family protein	-
GP482_RS00175 (GP482_00175)	-	29694..30398 (+)	705	WP_158913158.1	histidine phosphatase family protein	-
GP482_RS00180 (GP482_00180)	-	30382..31158 (+)	777	WP_158913160.1	D-alanyl-D-alanine carboxypeptidase family protein	-
GP482_RS00185 (GP482_00185)	-	31155..31745 (+)	591	WP_158913162.1	glucosaminidase domain-containing protein	-

Sequence

Protein

• Length: 158 a.a.
• Molecular weight: 19427.34 Da
• Isoelectric Point: 9.6123

>NTDB_id=409090 GP482_RS00160 WP_039696070.1 27177..27653(+) (comX/sigX) [Streptococcus ruminicola strain CNU_77-61]
MDFERYFQTVKPIILKLRRHYFVKLWDYEDWIQEGRIVFFQLLEEHPDLLINEGKRYSYFKTKFSNHVKDIIRHQESFKR
KFNRMPYEEIGDISHCVPQVSFFEVADYVAYQDSLARLRRTLGREDRLKLEKVIRGERFEGKKAFLKSIEPYFSDFRP

Nucleotide

• Length: 477 bp

>NTDB_id=409090 GP482_RS00160 WP_039696070.1 27177..27653(+) (comX/sigX) [Streptococcus ruminicola strain CNU_77-61]
GTGGATTTTGAACGCTATTTTCAAACCGTTAAACCAATTATTTTAAAATTACGCCGTCATTATTTTGTCAAACTTTGGGA
TTATGAAGATTGGATTCAAGAAGGTCGAATTGTTTTCTTTCAACTCTTAGAGGAGCATCCAGACCTCTTAATTAATGAAG
GCAAACGTTATAGTTACTTTAAAACAAAGTTTTCTAACCATGTTAAAGATATTATCCGCCATCAGGAATCCTTTAAACGG
AAATTTAATCGTATGCCTTATGAAGAAATTGGTGATATTAGTCACTGTGTGCCCCAGGTATCTTTCTTTGAAGTCGCAGA
TTACGTGGCTTATCAGGATAGCTTAGCACGTTTACGAAGAACATTGGGAAGAGAAGACCGACTAAAGTTGGAAAAAGTGA
TTCGTGGGGAACGTTTTGAAGGGAAGAAAGCCTTCTTAAAAAGCATCGAACCCTATTTCTCAGATTTTAGACCATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A091BY39

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	95.57	100	0.956
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	50.667	94.937	0.481
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	50.667	94.937	0.481
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	50.667	94.937	0.481
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	50.667	94.937	0.481
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	50.667	94.937	0.481
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	50.667	94.937	0.481
comX/sigX	Streptococcus mutans UA159	46.154	98.734	0.456
comX	Streptococcus sobrinus strain NIDR 6715-7	45.455	97.468	0.443
comX	Streptococcus thermophilus LMD-9	41.026	98.734	0.405
comX	Streptococcus thermophilus LMG 18311	41.026	98.734	0.405
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	39.241	100	0.392
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	39.241	100	0.392
comX/sigX	Streptococcus salivarius strain HSISS4	39.744	98.734	0.392
comX	Streptococcus salivarius SK126	39.744	98.734	0.392
comX/sigX	Streptococcus suis D9	38.854	99.367	0.386
comX/sigX	Streptococcus suis isolate S10	38.854	99.367	0.386
comX/sigX	Streptococcus suis P1/7	38.854	99.367	0.386