Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   GPA00_RS03630 Genome accession   NZ_CP046629
Coordinates   706026..706967 (+) Length   313 a.a.
NCBI ID   WP_027968018.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU G6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 701026..711967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPA00_RS03620 (GPA00_03620) rpoC 701784..705422 (+) 3639 WP_074639723.1 DNA-directed RNA polymerase subunit beta' -
  GPA00_RS03625 (GPA00_03625) - 705589..705957 (+) 369 WP_094140982.1 DUF1033 family protein -
  GPA00_RS03630 (GPA00_03630) comYA 706026..706967 (+) 942 WP_027968018.1 competence type IV pilus ATPase ComGA Machinery gene
  GPA00_RS03635 (GPA00_03635) comYB 706891..707934 (+) 1044 WP_167697815.1 competence type IV pilus assembly protein ComGB Machinery gene
  GPA00_RS03640 (GPA00_03640) comYC 707934..708236 (+) 303 WP_021141433.1 competence type IV pilus major pilin ComGC Machinery gene
  GPA00_RS03645 (GPA00_03645) comGD 708211..708651 (+) 441 WP_157327520.1 competence type IV pilus minor pilin ComGD -
  GPA00_RS03650 (GPA00_03650) comYE 708605..708898 (+) 294 WP_074629067.1 competence type IV pilus minor pilin ComGE Machinery gene
  GPA00_RS03655 (GPA00_03655) comYF 708882..709319 (+) 438 WP_157327522.1 competence type IV pilus minor pilin ComGF Machinery gene
  GPA00_RS03660 (GPA00_03660) comGG 709348..709641 (+) 294 WP_268894141.1 competence type IV pilus minor pilin ComGG -
  GPA00_RS03665 (GPA00_03665) comYH 709695..710651 (+) 957 WP_024344497.1 class I SAM-dependent methyltransferase Machinery gene
  GPA00_RS03670 (GPA00_03670) - 710705..711904 (+) 1200 WP_045798327.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35736.86 Da        Isoelectric Point: 5.7732

>NTDB_id=406291 GPA00_RS03630 WP_027968018.1 706026..706967(+) (comYA) [Streptococcus equinus strain CNU G6]
MIQEKAKQLIRDAVEKNAQDIYIIPKAENYEIYQRIGEKRQFIQEVATDEMTSLISHFKFVAGMNVGEKRRSQLGSCDYA
FADDEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMRNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPGK
QVITIEDPVEIKQDNMLQLQLNDEIGMTYDNLIKLSLRHRPDILIIGEIRDSETARAVIRASLTGVLVFSTIHAKSIPGV
YARLLELGVSRQELENSLRAIVYQRLIGGGGVVDFAKRDFEQYPPTRWNEQIDSLARDGHISFEEAKIEKIAL

Nucleotide


Download         Length: 942 bp        

>NTDB_id=406291 GPA00_RS03630 WP_027968018.1 706026..706967(+) (comYA) [Streptococcus equinus strain CNU G6]
ATGATTCAGGAAAAAGCAAAGCAGCTCATTAGAGATGCGGTTGAAAAGAATGCTCAGGATATCTATATTATTCCAAAGGC
AGAAAACTATGAGATTTATCAACGAATTGGTGAGAAACGTCAGTTTATTCAAGAAGTTGCTACTGATGAAATGACAAGCT
TGATTAGCCACTTTAAATTTGTAGCTGGGATGAATGTTGGTGAAAAGCGTCGTAGTCAGCTTGGTTCTTGTGACTATGCT
TTTGCAGATGATGAGGAGATTTCACTGCGCTTGTCTAGTGTGGGTGATTATCGTGGGCGTGAAAGTCTGGTCATTAGGCT
CCTTTATTCAGGTCGTCATGATTTGCAGTATTGGTTTGATGGAATGAGAAATATTTTAGAGGCTATTGACAGTAGGGGAC
TTTACCTTTTTTCCGGGCCGGTAGGGAGTGGGAAAACCACTCTCATGTACCAATTAGTTCGTGAAAAATTTCCTGGAAAG
CAGGTGATTACGATTGAAGACCCTGTTGAGATAAAACAAGACAATATGTTGCAATTGCAGTTGAATGATGAAATCGGGAT
GACTTATGATAATCTTATCAAGCTCTCGCTTCGTCATAGACCTGATATTTTGATTATTGGTGAGATTCGTGATAGTGAGA
CAGCGCGTGCGGTTATTAGAGCTAGTCTGACAGGAGTCCTTGTTTTTTCAACTATTCATGCGAAGAGTATACCTGGCGTT
TATGCTAGACTATTAGAATTGGGTGTTAGTAGGCAGGAACTTGAAAATAGCTTGCGCGCTATCGTTTATCAACGATTAAT
TGGTGGTGGAGGTGTAGTTGATTTTGCCAAAAGAGATTTTGAGCAGTATCCCCCAACAAGGTGGAATGAGCAAATTGATA
GCCTTGCTCGAGACGGACATATCAGTTTTGAAGAGGCAAAAATCGAAAAAATTGCCCTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

71.061

99.361

0.706
  comYA Streptococcus mutans UA140

70.74

99.361

0.703
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.71

99.042

0.681
  comYA Streptococcus gordonii str. Challis substr. CH1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.103

99.681

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

54.952

100

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

42.701

87.54

0.374

Multiple sequence alignment