Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   GPA00_RS03635 Genome accession   NZ_CP046629
Coordinates   706891..707934 (+) Length   347 a.a.
NCBI ID   WP_167697815.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU G6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 701891..712934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPA00_RS03625 (GPA00_03625) - 705589..705957 (+) 369 WP_094140982.1 DUF1033 family protein -
  GPA00_RS03630 (GPA00_03630) comYA 706026..706967 (+) 942 WP_027968018.1 competence type IV pilus ATPase ComGA Machinery gene
  GPA00_RS03635 (GPA00_03635) comYB 706891..707934 (+) 1044 WP_167697815.1 competence type IV pilus assembly protein ComGB Machinery gene
  GPA00_RS03640 (GPA00_03640) comYC 707934..708236 (+) 303 WP_021141433.1 competence type IV pilus major pilin ComGC Machinery gene
  GPA00_RS03645 (GPA00_03645) comGD 708211..708651 (+) 441 WP_157327520.1 competence type IV pilus minor pilin ComGD -
  GPA00_RS03650 (GPA00_03650) comYE 708605..708898 (+) 294 WP_074629067.1 competence type IV pilus minor pilin ComGE Machinery gene
  GPA00_RS03655 (GPA00_03655) comYF 708882..709319 (+) 438 WP_157327522.1 competence type IV pilus minor pilin ComGF Machinery gene
  GPA00_RS03660 (GPA00_03660) comGG 709348..709641 (+) 294 WP_268894141.1 competence type IV pilus minor pilin ComGG -
  GPA00_RS03665 (GPA00_03665) comYH 709695..710651 (+) 957 WP_024344497.1 class I SAM-dependent methyltransferase Machinery gene
  GPA00_RS03670 (GPA00_03670) - 710705..711904 (+) 1200 WP_045798327.1 acetate kinase -
  GPA00_RS03675 (GPA00_03675) - 712062..712259 (+) 198 WP_027968026.1 helix-turn-helix transcriptional regulator -
  GPA00_RS03680 (GPA00_03680) - 712315..712767 (+) 453 WP_074483978.1 ABC transporter permease -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39733.11 Da        Isoelectric Point: 9.6792

>NTDB_id=406292 GPA00_RS03635 WP_167697815.1 706891..707934(+) (comYB) [Streptococcus equinus strain CNU G6]
MSKLIALLETDISVLKRQKSKKLPFKKQQKVIQLFNNLFNSGFTLTEIVSFLRRSQLLQESYVDSMQESLLSGATLADMM
ARLGFSDTIVTQIALADVHGNCQQSLVKIDRYLASMSVVRKKLIEVATYPLILLSFLILIMLGLKNYLLPQLESQNFATQ
IIAHFPMIFLGSFVLLGLAVVLGFFYARRLSPIYLFSQISRLPIVGRFIRLYLTAYYAREWGNLIGQGIDLMEIVALMQH
QKSRLFQEIGKDMQQALLSGQSFHQKVLDYPFFLRELSLMIEYGEVKSKLGRELDIYAEETWQTFFSQLTQATQLIQPLV
FVFVALIIVLIYVAMLLPMYQNMGGNF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=406292 GPA00_RS03635 WP_167697815.1 706891..707934(+) (comYB) [Streptococcus equinus strain CNU G6]
ATGAGCAAATTGATAGCCTTGCTCGAGACGGACATATCAGTTTTGAAGAGGCAAAAATCGAAAAAATTGCCCTTTAAGAA
ACAACAGAAGGTCATTCAATTATTTAATAATTTGTTTAACAGTGGCTTTACTTTAACTGAAATAGTGTCCTTTTTGAGAC
GGAGTCAGTTATTGCAGGAATCTTATGTGGATAGCATGCAGGAGTCCTTGCTGAGTGGCGCAACTTTAGCAGATATGATG
GCAAGGTTAGGCTTTTCAGACACGATTGTGACTCAGATTGCTTTGGCTGATGTTCATGGAAATTGTCAGCAAAGTCTTGT
AAAAATCGATCGTTATTTGGCTAGCATGTCTGTTGTGCGAAAGAAGTTGATTGAAGTAGCGACCTATCCTTTGATTTTAT
TAAGTTTTTTGATTTTGATAATGCTTGGCTTAAAAAATTATTTATTGCCGCAACTTGAAAGTCAAAATTTTGCTACTCAG
ATTATTGCCCATTTTCCAATGATTTTCCTGGGGAGCTTTGTGCTTTTAGGACTAGCAGTTGTTCTAGGATTTTTCTATGC
TAGGCGTTTATCACCAATCTATCTTTTTAGCCAGATTAGTCGCTTGCCGATAGTAGGACGATTCATTCGCCTTTATCTGA
CTGCTTATTATGCGCGTGAATGGGGAAATCTCATTGGGCAGGGGATTGATTTGATGGAAATTGTAGCATTGATGCAGCAC
CAAAAGTCGCGTCTTTTTCAAGAGATTGGTAAGGATATGCAGCAAGCTCTTTTATCTGGTCAATCATTTCACCAAAAGGT
CTTAGATTATCCCTTCTTTTTGAGGGAACTGAGCCTGATGATTGAGTACGGAGAAGTTAAGTCAAAACTTGGTCGGGAGC
TTGATATCTATGCTGAGGAAACATGGCAGACTTTCTTTAGCCAGTTAACTCAGGCAACACAGTTGATTCAACCGCTGGTT
TTTGTCTTTGTTGCTTTAATTATTGTTTTAATCTACGTGGCAATGCTTTTGCCAATGTATCAAAATATGGGAGGAAATTT
TTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

63.158

98.559

0.622
  comYB Streptococcus mutans UA159

62.865

98.559

0.62
  comYB Streptococcus gordonii str. Challis substr. CH1

58.892

98.847

0.582
  comGB/cglB Streptococcus mitis NCTC 12261

58.16

97.118

0.565
  comGB/cglB Streptococcus mitis SK321

57.567

97.118

0.559
  comGB/cglB Streptococcus pneumoniae Rx1

56.973

97.118

0.553
  comGB/cglB Streptococcus pneumoniae D39

56.973

97.118

0.553
  comGB/cglB Streptococcus pneumoniae R6

56.973

97.118

0.553
  comGB/cglB Streptococcus pneumoniae TIGR4

56.973

97.118

0.553
  comGB Lactococcus lactis subsp. cremoris KW2

50.592

97.406

0.493

Multiple sequence alignment