Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   GO596_RS02345 Genome accession   NZ_CP046628
Coordinates   480031..480972 (-) Length   313 a.a.
NCBI ID   WP_027968018.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU 77-23     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 475031..485972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO596_RS02305 (GO596_02305) - 475094..476293 (-) 1200 WP_045798327.1 acetate kinase -
  GO596_RS02310 (GO596_02310) comYH 476347..477303 (-) 957 WP_157339147.1 class I SAM-dependent methyltransferase Machinery gene
  GO596_RS02315 (GO596_02315) comGG 477357..477692 (-) 336 WP_198362600.1 competence type IV pilus minor pilin ComGG -
  GO596_RS02320 (GO596_02320) comYF 477679..478116 (-) 438 WP_157339148.1 competence type IV pilus minor pilin ComGF Machinery gene
  GO596_RS02325 (GO596_02325) comYE 478100..478393 (-) 294 WP_157339149.1 competence type IV pilus minor pilin ComGE Machinery gene
  GO596_RS02330 (GO596_02330) comGD 478347..478787 (-) 441 WP_074534076.1 competence type IV pilus minor pilin ComGD -
  GO596_RS02335 (GO596_02335) comYC 478762..479064 (-) 303 WP_021141433.1 competence type IV pilus major pilin ComGC Machinery gene
  GO596_RS02340 (GO596_02340) comYB 479064..480107 (-) 1044 WP_198289264.1 competence type IV pilus assembly protein ComGB Machinery gene
  GO596_RS02345 (GO596_02345) comYA 480031..480972 (-) 942 WP_027968018.1 competence type IV pilus ATPase ComGA Machinery gene
  GO596_RS02350 (GO596_02350) - 481041..481409 (-) 369 WP_021141429.1 DUF1033 family protein -
  GO596_RS02355 (GO596_02355) rpoC 481577..485215 (-) 3639 WP_157339150.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35736.86 Da        Isoelectric Point: 5.7732

>NTDB_id=406227 GO596_RS02345 WP_027968018.1 480031..480972(-) (comYA) [Streptococcus equinus strain CNU 77-23]
MIQEKAKQLIRDAVEKNAQDIYIIPKAENYEIYQRIGEKRQFIQEVATDEMTSLISHFKFVAGMNVGEKRRSQLGSCDYA
FADDEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMRNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPGK
QVITIEDPVEIKQDNMLQLQLNDEIGMTYDNLIKLSLRHRPDILIIGEIRDSETARAVIRASLTGVLVFSTIHAKSIPGV
YARLLELGVSRQELENSLRAIVYQRLIGGGGVVDFAKRDFEQYPPTRWNEQIDSLARDGHISFEEAKIEKIAL

Nucleotide


Download         Length: 942 bp        

>NTDB_id=406227 GO596_RS02345 WP_027968018.1 480031..480972(-) (comYA) [Streptococcus equinus strain CNU 77-23]
ATGATTCAGGAAAAAGCAAAGCAGCTCATTAGAGATGCGGTTGAAAAGAATGCTCAGGATATCTATATTATTCCAAAGGC
AGAAAACTATGAGATTTATCAACGAATTGGTGAGAAGCGCCAGTTTATTCAAGAAGTTGCTACTGATGAAATGACAAGCT
TGATTAGTCACTTTAAATTTGTAGCTGGGATGAATGTTGGTGAAAAGCGTCGTAGTCAGCTTGGTTCTTGTGACTATGCT
TTTGCAGATGATGAGGAGATTTCACTGCGCTTGTCTAGTGTGGGTGATTATCGTGGGCGTGAAAGTCTGGTCATTAGGCT
CCTTTATTCAGGTCGTCATGATTTGCAGTATTGGTTTGATGGAATGAGAAATATTTTAGAGGCTATTGACAGCAGGGGAC
TTTACCTTTTTTCCGGGCCGGTAGGGAGTGGGAAAACCACTCTCATGTACCAATTAGTTCGTGAAAAATTTCCTGGAAAG
CAGGTGATTACGATTGAAGACCCTGTTGAGATAAAACAAGACAATATGTTGCAATTGCAGTTAAATGATGAAATCGGGAT
GACTTATGATAATCTTATCAAGCTCTCGCTTCGTCATAGACCTGATATTTTGATTATTGGTGAGATTCGTGATAGCGAGA
CAGCGCGTGCGGTTATTAGAGCTAGTCTGACAGGAGTCCTTGTTTTTTCAACCATTCATGCGAAAAGTATTCCAGGCGTT
TATGCTAGACTATTAGAATTGGGTGTTAGTAGGCAGGAACTTGAAAATAGCTTGCGCGCTATCGTTTATCAACGATTAAT
TGGTGGTGGAGGTGTAGTTGATTTTGCCAAAAGAGATTTTGAGCAGTATCCCCCAACAAGGTGGAATGAGCAAATTGATA
GCCTTGCTCGAGACGGACATATCAGTTTTGAAGAGGCAAAAATCGAAAAAATTGCCCTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

71.061

99.361

0.706
  comYA Streptococcus mutans UA140

70.74

99.361

0.703
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.71

99.042

0.681
  comYA Streptococcus gordonii str. Challis substr. CH1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.103

99.681

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

54.952

100

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

42.701

87.54

0.374

Multiple sequence alignment