Detailed information
Bioinformatically predicted
Overview
| Name | comGC/cglC | Type | Machinery gene |
| Locus tag | GL185_RS08555 | Genome accession | NZ_CP046357 |
| Coordinates | 1708195..1708521 (+) | Length | 108 a.a. |
| NCBI ID | WP_000738625.1 | Uniprot ID | - |
| Organism | Streptococcus pneumoniae strain 525 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 1703195..1713521
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GL185_RS08530 (GL185_08680) | nagA | 1703325..1704476 (+) | 1152 | WP_001134457.1 | N-acetylglucosamine-6-phosphate deacetylase | - |
| GL185_RS08535 (GL185_08685) | - | 1704639..1705697 (+) | 1059 | WP_000649471.1 | zinc-dependent alcohol dehydrogenase family protein | - |
| GL185_RS08540 (GL185_08690) | - | 1705848..1706213 (+) | 366 | WP_000286415.1 | DUF1033 family protein | - |
| GL185_RS08545 (GL185_08695) | comGA/cglA/cilD | 1706288..1707229 (+) | 942 | WP_000249555.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| GL185_RS08550 (GL185_08700) | comGB/cglB | 1707177..1708193 (+) | 1017 | WP_074017570.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| GL185_RS08555 (GL185_08705) | comGC/cglC | 1708195..1708521 (+) | 327 | WP_000738625.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| GL185_RS08560 (GL185_08710) | comGD/cglD | 1708514..1708918 (+) | 405 | WP_000588030.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| GL185_RS08565 (GL185_08715) | comGE/cglE | 1708881..1709183 (+) | 303 | WP_000413382.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| GL185_RS08570 (GL185_08720) | comGF/cglF | 1709146..1709607 (+) | 462 | WP_000250539.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| GL185_RS08575 (GL185_08725) | comGG/cglG | 1709585..1710031 (+) | 447 | WP_001811371.1 | competence type IV pilus minor pilin ComGG | Machinery gene |
| GL185_RS08580 (GL185_08730) | - | 1710134..1710721 (+) | 588 | WP_000679779.1 | class I SAM-dependent methyltransferase | - |
| GL185_RS08585 (GL185_08735) | comYH | 1710782..1711735 (+) | 954 | WP_000345122.1 | class I SAM-dependent methyltransferase | Machinery gene |
| GL185_RS08590 (GL185_08740) | - | 1711786..1712976 (+) | 1191 | WP_000167765.1 | acetate kinase | - |
| GL185_RS11460 | - | 1712977..1713108 (+) | 132 | WP_000768904.1 | hypothetical protein | - |
| GL185_RS08595 (GL185_08745) | rnpA | 1713125..1713496 (+) | 372 | WP_000739247.1 | ribonuclease P protein component | - |
Sequence
Protein
Download Length: 108 a.a. Molecular weight: 12143.28 Da Isoelectric Point: 10.0055
>NTDB_id=403196 GL185_RS08555 WP_000738625.1 1708195..1708521(+) (comGC/cglC) [Streptococcus pneumoniae strain 525]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND
Nucleotide
Download Length: 327 bp
>NTDB_id=403196 GL185_RS08555 WP_000738625.1 1708195..1708521(+) (comGC/cglC) [Streptococcus pneumoniae strain 525]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTAGTAGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGATAAAAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTAGTAGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGATAAAAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGC/cglC | Streptococcus mitis SK321 |
95.37 |
100 |
0.954 |
| comGC/cglC | Streptococcus pneumoniae Rx1 |
92.593 |
100 |
0.926 |
| comGC/cglC | Streptococcus pneumoniae D39 |
92.593 |
100 |
0.926 |
| comGC/cglC | Streptococcus pneumoniae R6 |
92.593 |
100 |
0.926 |
| comGC/cglC | Streptococcus pneumoniae TIGR4 |
92.593 |
100 |
0.926 |
| comGC/cglC | Streptococcus mitis NCTC 12261 |
92.857 |
90.741 |
0.843 |
| comYC | Streptococcus gordonii str. Challis substr. CH1 |
67.961 |
95.37 |
0.648 |
| comYC | Streptococcus mutans UA140 |
62.745 |
94.444 |
0.593 |
| comYC | Streptococcus mutans UA159 |
62.745 |
94.444 |
0.593 |
| comGC | Lactococcus lactis subsp. cremoris KW2 |
56.863 |
94.444 |
0.537 |
| comYC | Streptococcus suis isolate S10 |
64.773 |
81.481 |
0.528 |
| comGC | Staphylococcus aureus MW2 |
47.674 |
79.63 |
0.38 |
| comGC | Staphylococcus aureus N315 |
47.674 |
79.63 |
0.38 |