Detailed information NTG0403199

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: GL185_RS08570
• Genome accession: NZ_CP046357
• Coordinates: 1709146..1709607 (+)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 525
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1704146..1714607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL185_RS08535 (GL185_08685)	-	1704639..1705697 (+)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-
GL185_RS08540 (GL185_08690)	-	1705848..1706213 (+)	366	WP_000286415.1	DUF1033 family protein	-
GL185_RS08545 (GL185_08695)	comGA/cglA/cilD	1706288..1707229 (+)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
GL185_RS08550 (GL185_08700)	comGB/cglB	1707177..1708193 (+)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
GL185_RS08555 (GL185_08705)	comGC/cglC	1708195..1708521 (+)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
GL185_RS08560 (GL185_08710)	comGD/cglD	1708514..1708918 (+)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
GL185_RS08565 (GL185_08715)	comGE/cglE	1708881..1709183 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
GL185_RS08570 (GL185_08720)	comGF/cglF	1709146..1709607 (+)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
GL185_RS08575 (GL185_08725)	comGG/cglG	1709585..1710031 (+)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
GL185_RS08580 (GL185_08730)	-	1710134..1710721 (+)	588	WP_000679779.1	class I SAM-dependent methyltransferase	-
GL185_RS08585 (GL185_08735)	comYH	1710782..1711735 (+)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
GL185_RS08590 (GL185_08740)	-	1711786..1712976 (+)	1191	WP_000167765.1	acetate kinase	-
GL185_RS11460	-	1712977..1713108 (+)	132	WP_000768904.1	hypothetical protein	-
GL185_RS08595 (GL185_08745)	rnpA	1713125..1713496 (+)	372	WP_000739247.1	ribonuclease P protein component	-
GL185_RS08600 (GL185_08750)	-	1713471..1714295 (+)	825	WP_000727904.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=403199 GL185_RS08570 WP_000250539.1 1709146..1709607(+) (comGF/cglF) [Streptococcus pneumoniae strain 525]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=403199 GL185_RS08570 WP_000250539.1 1709146..1709607(+) (comGF/cglF) [Streptococcus pneumoniae strain 525]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915