Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FY406_RS04140 Genome accession   NZ_CP043405
Coordinates   849479..850420 (+) Length   313 a.a.
NCBI ID   WP_003086841.1    Uniprot ID   -
Organism   Streptococcus ratti strain ATCC 31377     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 844479..855420
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS04120 (FY406_04120) - 846054..846422 (+) 369 WP_003086846.1 DUF1033 family protein -
  FY406_RS04125 (FY406_04125) - 846670..847278 (+) 609 WP_003086844.1 PepSY domain-containing protein -
  FY406_RS04130 (FY406_04130) - 847422..848114 (+) 693 WP_003086843.1 response regulator transcription factor -
  FY406_RS04135 (FY406_04135) - 848077..849426 (+) 1350 WP_003086842.1 cell wall metabolism sensor histidine kinase WalK -
  FY406_RS04140 (FY406_04140) comYA 849479..850420 (+) 942 WP_003086841.1 competence type IV pilus ATPase ComGA Machinery gene
  FY406_RS04145 (FY406_04145) comYB 850344..851387 (+) 1044 WP_404827213.1 competence type IV pilus assembly protein ComGB Machinery gene
  FY406_RS04150 (FY406_04150) comYC 851387..851701 (+) 315 WP_003086839.1 competence type IV pilus major pilin ComGC Machinery gene
  FY406_RS04155 (FY406_04155) comYD 851688..852095 (+) 408 WP_003086838.1 competence type IV pilus minor pilin ComGD Machinery gene
  FY406_RS04160 (FY406_04160) comYE 852067..852360 (+) 294 WP_003086837.1 competence type IV pilus minor pilin ComGE Machinery gene
  FY406_RS04165 (FY406_04165) comYF 852347..852781 (+) 435 WP_003086836.1 competence type IV pilus minor pilin ComGF Machinery gene
  FY406_RS04170 (FY406_04170) comYG 852759..853166 (+) 408 WP_003091335.1 competence type IV pilus minor pilin ComGG Machinery gene
  FY406_RS04175 (FY406_04175) comYH 853215..854168 (+) 954 WP_003086833.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35800.12 Da        Isoelectric Point: 7.5049

>NTDB_id=383566 FY406_RS04140 WP_003086841.1 849479..850420(+) (comYA) [Streptococcus ratti strain ATCC 31377]
MVQDLGKKIIAQAVEEKAQDIYMIPRAEAYELYMRIGDERRFIDDYEHQFMANLISHFKFVAGMNVGEKRRSQLGACDYH
YDDGKTISLRLSSVGDYRGYESLVIRLLFDGRHDLKFWFNGMKLILKEIKGRGLYLFSGPVGSGKTTLMYQLVKEKFSSK
QVITIEDPVEIKQDNMLQLQLNESIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGAVVFSTVHAKSIPGV
YARLLELGVSQEELGNALRGIAYQRLIKGGGVIDFAQRNYQKHSAQRWNKQIDSLFAEGYITKEEAETEKIEE

Nucleotide


Download         Length: 942 bp        

>NTDB_id=383566 FY406_RS04140 WP_003086841.1 849479..850420(+) (comYA) [Streptococcus ratti strain ATCC 31377]
ATGGTTCAGGATTTAGGGAAAAAAATAATTGCTCAGGCAGTTGAGGAAAAGGCGCAGGATATTTATATGATCCCGCGGGC
GGAAGCTTATGAGCTTTACATGAGGATCGGTGATGAAAGGAGATTTATTGATGATTACGAACATCAGTTTATGGCAAATC
TAATCAGCCATTTTAAATTTGTCGCAGGAATGAATGTTGGTGAGAAGAGACGAAGCCAGCTAGGAGCTTGTGATTATCAT
TATGATGACGGCAAGACCATCTCTTTACGGCTGTCAAGTGTCGGGGATTACCGCGGTTACGAAAGTTTGGTCATTCGTCT
CTTATTTGACGGCCGTCACGATTTAAAATTCTGGTTTAATGGTATGAAGCTCATTTTAAAGGAAATCAAGGGGAGGGGAC
TTTATCTTTTTTCAGGACCAGTTGGCAGCGGGAAAACTACCCTTATGTACCAGCTTGTTAAGGAGAAATTTAGCAGCAAG
CAGGTAATCACTATTGAAGATCCCGTGGAAATTAAACAAGACAATATGCTGCAGCTGCAGCTTAATGAAAGTATTGATAT
GACTTATGACAGTCTTATTAAGCTGTCTCTTAGGCATCGGCCCGACGTTTTGATTATTGGGGAAATCAGAGATAAGGAGA
CCGCGCGAGCGGTTATTAGAGCGAGTCTGACTGGGGCGGTTGTCTTTTCAACTGTTCATGCTAAAAGTATTCCCGGCGTC
TATGCCAGACTGCTGGAATTGGGTGTCAGCCAAGAGGAGCTGGGAAATGCTTTGCGTGGAATTGCTTACCAACGTTTAAT
TAAGGGAGGAGGTGTAATTGATTTTGCCCAAAGAAACTACCAGAAACATTCAGCTCAAAGGTGGAATAAGCAAATTGACA
GCCTTTTTGCAGAAGGATATATCACTAAGGAAGAAGCCGAAACAGAAAAAATTGAAGAGTGA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

83.067

100

0.831
  comYA Streptococcus mutans UA140

82.748

100

0.827
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

70.513

99.681

0.703
  comYA Streptococcus gordonii str. Challis substr. CH1

70.418

99.361

0.7
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

66.881

99.361

0.665
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

66.881

99.361

0.665
  comGA/cglA/cilD Streptococcus pneumoniae D39

66.881

99.361

0.665
  comGA/cglA/cilD Streptococcus pneumoniae R6

66.881

99.361

0.665
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

66.881

99.361

0.665
  comGA Lactococcus lactis subsp. cremoris KW2

52.885

99.681

0.527

Multiple sequence alignment