Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FY406_RS04145 Genome accession   NZ_CP043405
Coordinates   850344..851387 (+) Length   347 a.a.
NCBI ID   WP_404827213.1    Uniprot ID   -
Organism   Streptococcus ratti strain ATCC 31377     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 845344..856387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS04120 (FY406_04120) - 846054..846422 (+) 369 WP_003086846.1 DUF1033 family protein -
  FY406_RS04125 (FY406_04125) - 846670..847278 (+) 609 WP_003086844.1 PepSY domain-containing protein -
  FY406_RS04130 (FY406_04130) - 847422..848114 (+) 693 WP_003086843.1 response regulator transcription factor -
  FY406_RS04135 (FY406_04135) - 848077..849426 (+) 1350 WP_003086842.1 cell wall metabolism sensor histidine kinase WalK -
  FY406_RS04140 (FY406_04140) comYA 849479..850420 (+) 942 WP_003086841.1 competence type IV pilus ATPase ComGA Machinery gene
  FY406_RS04145 (FY406_04145) comYB 850344..851387 (+) 1044 WP_404827213.1 competence type IV pilus assembly protein ComGB Machinery gene
  FY406_RS04150 (FY406_04150) comYC 851387..851701 (+) 315 WP_003086839.1 competence type IV pilus major pilin ComGC Machinery gene
  FY406_RS04155 (FY406_04155) comYD 851688..852095 (+) 408 WP_003086838.1 competence type IV pilus minor pilin ComGD Machinery gene
  FY406_RS04160 (FY406_04160) comYE 852067..852360 (+) 294 WP_003086837.1 competence type IV pilus minor pilin ComGE Machinery gene
  FY406_RS04165 (FY406_04165) comYF 852347..852781 (+) 435 WP_003086836.1 competence type IV pilus minor pilin ComGF Machinery gene
  FY406_RS04170 (FY406_04170) comYG 852759..853166 (+) 408 WP_003091335.1 competence type IV pilus minor pilin ComGG Machinery gene
  FY406_RS04175 (FY406_04175) comYH 853215..854168 (+) 954 WP_003086833.1 class I SAM-dependent methyltransferase Machinery gene
  FY406_RS04180 (FY406_04180) - 854228..855427 (+) 1200 WP_003086832.1 acetate kinase -
  FY406_RS04185 (FY406_04185) - 855630..856307 (+) 678 WP_003086831.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40092.67 Da        Isoelectric Point: 9.8876

>NTDB_id=383567 FY406_RS04145 WP_404827213.1 850344..851387(+) (comYB) [Streptococcus ratti strain ATCC 31377]
MSKLTAFLQKDISLRKKPKQKKLKSEKQRKVIQLFNNLFASGFNLTEIVDFLERSRLLAKVYTDSMRQGLLNGLNLAEIM
SSLGFSDNVVTQLALSEIHGNTHKSLLKIESYLSNLIVVKKKLIEVATYPVILIIFLILIMLGLKNYLLPQLENGNFATE
LISHFPFIFLLVCGFFIFLTGFLYFSSRRMSQIRLVAVCSQLPFVGSYFRLYLTAYYAREWGNLIGQGVEMSQIVRLMQK
QKSKLFREIGKDMEIALISGREFHQKVLDYPFFLRELSLMIEYGEVKSKLGSELEIYAEESWEHFFSRLNKAMQLIQPLV
FVLVAVIIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=383567 FY406_RS04145 WP_404827213.1 850344..851387(+) (comYB) [Streptococcus ratti strain ATCC 31377]
ATAAGCAAATTGACAGCCTTTTTGCAGAAGGATATATCACTAAGGAAGAAGCCGAAACAGAAAAAATTGAAGAGTGAAAA
ACAAAGGAAAGTTATTCAATTATTTAATAATCTTTTTGCCAGCGGCTTCAACCTGACTGAAATTGTAGATTTTTTAGAGC
GAAGCCGCTTACTGGCAAAGGTTTACACAGACAGCATGCGTCAAGGGCTTCTAAACGGCTTGAATCTAGCGGAAATAATG
AGTTCCTTAGGTTTTTCAGACAATGTCGTTACACAGTTGGCGCTTTCTGAAATTCATGGGAATACTCATAAAAGTCTCTT
AAAGATCGAGTCCTACTTAAGCAACCTTATTGTTGTTAAAAAGAAACTAATTGAGGTAGCTACCTATCCTGTTATTTTAA
TCATTTTTCTTATTCTCATCATGCTAGGATTAAAAAATTACCTGCTTCCTCAGCTTGAAAATGGAAATTTTGCGACAGAA
CTTATTTCTCATTTTCCGTTTATTTTTCTCTTAGTCTGCGGATTTTTCATATTTTTAACGGGATTTCTTTATTTTTCTTC
AAGACGAATGAGCCAGATTCGCTTAGTGGCAGTTTGCAGTCAGTTACCATTTGTTGGCAGCTATTTTCGGCTGTATTTGA
CAGCTTATTATGCACGAGAATGGGGTAATCTTATAGGACAGGGAGTAGAGATGTCTCAGATTGTTCGCTTGATGCAAAAG
CAAAAATCAAAGCTCTTTAGAGAAATAGGTAAGGATATGGAAATAGCACTTATATCCGGTCGGGAATTTCATCAGAAAGT
TTTAGACTATCCTTTCTTTTTGAGAGAGCTTAGCCTAATGATTGAATATGGGGAGGTAAAGTCAAAGCTGGGCAGTGAGC
TTGAGATCTATGCTGAGGAGAGTTGGGAACATTTCTTTAGCAGACTCAATAAGGCTATGCAACTCATCCAGCCTCTTGTC
TTTGTTCTGGTAGCGGTGATTATCGTGATGATTTATGCGGCAATGCTGCTGCCGATTTATCAAAATATGGAGGTCAATTT
GTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

79.24

98.559

0.781
  comYB Streptococcus mutans UA159

78.947

98.559

0.778
  comYB Streptococcus gordonii str. Challis substr. CH1

63.372

99.135

0.628
  comGB/cglB Streptococcus mitis NCTC 12261

58.702

97.695

0.573
  comGB/cglB Streptococcus mitis SK321

58.036

96.83

0.562
  comGB/cglB Streptococcus pneumoniae Rx1

57.44

96.83

0.556
  comGB/cglB Streptococcus pneumoniae D39

57.44

96.83

0.556
  comGB/cglB Streptococcus pneumoniae R6

57.44

96.83

0.556
  comGB/cglB Streptococcus pneumoniae TIGR4

57.44

96.83

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

53.412

97.118

0.519

Multiple sequence alignment