Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EQH42_RS09360 Genome accession   NZ_CP035238
Coordinates   1841261..1841587 (-) Length   108 a.a.
NCBI ID   WP_000738626.1    Uniprot ID   Q8DN88
Organism   Streptococcus pneumoniae strain TVO_D39     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1836261..1846587
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH42_RS09320 (EQH42_09850) rnpA 1836278..1836649 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH42_RS10480 - 1836666..1836797 (-) 132 WP_000768904.1 hypothetical protein -
  EQH42_RS09325 (EQH42_09855) - 1836798..1837988 (-) 1191 WP_000167757.1 acetate kinase -
  EQH42_RS09330 (EQH42_09860) comYH 1838039..1838992 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  EQH42_RS09335 (EQH42_09865) - 1839053..1839647 (-) 595 Protein_1839 class I SAM-dependent methyltransferase -
  EQH42_RS09340 (EQH42_09870) comGG/cglG 1839784..1840197 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH42_RS09345 (EQH42_09875) comGF/cglF 1840175..1840636 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH42_RS09350 (EQH42_09880) comGE/cglE 1840599..1840901 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH42_RS09355 (EQH42_09885) comGD/cglD 1840864..1841268 (-) 405 WP_000588026.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH42_RS09360 (EQH42_09890) comGC/cglC 1841261..1841587 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  EQH42_RS09365 (EQH42_09895) comGB/cglB 1841589..1842605 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH42_RS09370 (EQH42_09900) comGA/cglA/cilD 1842553..1843494 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH42_RS09375 (EQH42_09905) - 1843570..1843935 (-) 366 WP_000286412.1 DUF1033 family protein -
  EQH42_RS09380 (EQH42_09910) - 1844086..1845144 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EQH42_RS09385 (EQH42_09915) nagA 1845307..1846458 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12200.38 Da        Isoelectric Point: 10.1877

>NTDB_id=336927 EQH42_RS09360 WP_000738626.1 1841261..1841587(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_D39]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQAKAYKEYHDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=336927 EQH42_RS09360 WP_000738626.1 1841261..1841587(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_D39]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 6Y1H

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

100

100

1
  comGC/cglC Streptococcus pneumoniae D39

100

100

1
  comGC/cglC Streptococcus pneumoniae R6

100

100

1
  comGC/cglC Streptococcus pneumoniae TIGR4

99.074

100

0.991
  comGC/cglC Streptococcus mitis SK321

94.444

100

0.944
  comGC/cglC Streptococcus mitis NCTC 12261

92.157

94.444

0.87
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus suis isolate S10

70.37

75

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

53.922

94.444

0.509
  comGC Staphylococcus aureus MW2

50

79.63

0.398
  comGC Staphylococcus aureus N315

50

79.63

0.398
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment