Detailed information NTG0336924

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH42_RS09345
• Genome accession: NZ_CP035238
• Coordinates: 1840175..1840636 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250534.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_D39
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1835175..1845636

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH42_RS09315 (EQH42_09845)	-	1835479..1836303 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH42_RS09320 (EQH42_09850)	rnpA	1836278..1836649 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH42_RS10480	-	1836666..1836797 (-)	132	WP_000768904.1	hypothetical protein	-
EQH42_RS09325 (EQH42_09855)	-	1836798..1837988 (-)	1191	WP_000167757.1	acetate kinase	-
EQH42_RS09330 (EQH42_09860)	comYH	1838039..1838992 (-)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
EQH42_RS09335 (EQH42_09865)	-	1839053..1839647 (-)	595	Protein_1839	class I SAM-dependent methyltransferase	-
EQH42_RS09340 (EQH42_09870)	comGG/cglG	1839784..1840197 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH42_RS09345 (EQH42_09875)	comGF/cglF	1840175..1840636 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH42_RS09350 (EQH42_09880)	comGE/cglE	1840599..1840901 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH42_RS09355 (EQH42_09885)	comGD/cglD	1840864..1841268 (-)	405	WP_000588026.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH42_RS09360 (EQH42_09890)	comGC/cglC	1841261..1841587 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
EQH42_RS09365 (EQH42_09895)	comGB/cglB	1841589..1842605 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH42_RS09370 (EQH42_09900)	comGA/cglA/cilD	1842553..1843494 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH42_RS09375 (EQH42_09905)	-	1843570..1843935 (-)	366	WP_000286412.1	DUF1033 family protein	-
EQH42_RS09380 (EQH42_09910)	-	1844086..1845144 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17972.67 Da
• Isoelectric Point: 9.6092

>NTDB_id=336924 EQH42_RS09345 WP_000250534.1 1840175..1840636(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_D39]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=336924 EQH42_RS09345 WP_000250534.1 1840175..1840636(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_D39]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGATGATTTCCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGACTCAAATCTGTACGGATTACAGAGGACAATCAACTGGTTCGCTTTCATT
TCCAGTTCCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	100	100	1
comGF/cglF	Streptococcus pneumoniae D39	100	100	1
comGF/cglF	Streptococcus pneumoniae R6	100	100	1
comGF/cglF	Streptococcus pneumoniae TIGR4	100	100	1
comGF/cglF	Streptococcus mitis SK321	90.85	100	0.909
comGF/cglF	Streptococcus mitis NCTC 12261	89.542	100	0.895