Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EQH46_RS09725 Genome accession   NZ_CP035234
Coordinates   1897440..1897766 (-) Length   108 a.a.
NCBI ID   WP_000738621.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1902277     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1892440..1902766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH46_RS09685 (EQH46_10195) rnpA 1892458..1892829 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH46_RS10905 - 1892846..1892977 (-) 132 WP_000768904.1 hypothetical protein -
  EQH46_RS09690 (EQH46_10200) - 1892978..1894168 (-) 1191 WP_000167768.1 acetate kinase -
  EQH46_RS09695 (EQH46_10205) comYH 1894219..1895172 (-) 954 WP_000345086.1 class I SAM-dependent methyltransferase Machinery gene
  EQH46_RS09700 (EQH46_10210) - 1895233..1895827 (-) 595 Protein_1916 class I SAM-dependent methyltransferase -
  EQH46_RS09705 (EQH46_10215) comGG/cglG 1895930..1896376 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH46_RS09710 (EQH46_10220) comGF/cglF 1896354..1896815 (-) 462 WP_000250523.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH46_RS09715 (EQH46_10225) comGE/cglE 1896778..1897080 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH46_RS09720 (EQH46_10230) comGD/cglD 1897043..1897447 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH46_RS09725 (EQH46_10235) comGC/cglC 1897440..1897766 (-) 327 WP_000738621.1 comG operon protein ComGC Machinery gene
  EQH46_RS09730 (EQH46_10240) comGB/cglB 1897768..1898784 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH46_RS09735 (EQH46_10245) comGA/cglA/cilD 1898732..1899673 (-) 942 WP_000249568.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH46_RS09740 (EQH46_10250) - 1899749..1900114 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH46_RS09745 (EQH46_10255) - 1900265..1901323 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EQH46_RS09750 (EQH46_10260) nagA 1901486..1902637 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12240.44 Da        Isoelectric Point: 10.1432

>NTDB_id=336624 EQH46_RS09725 WP_000738621.1 1897440..1897766(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1902277]
MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=336624 EQH46_RS09725 WP_000738621.1 1897440..1897766(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1902277]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGATTGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae D39

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae R6

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

94.444

100

0.944
  comGC/cglC Streptococcus mitis NCTC 12261

91.837

90.741

0.833
  comYC Streptococcus gordonii str. Challis substr. CH1

66.019

95.37

0.63
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

51.163

79.63

0.407
  comGC Staphylococcus aureus N315

51.163

79.63

0.407
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment