Detailed information NTG0331751

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: EHW89_RS01045
• Genome accession: NZ_CP034543
• Coordinates: 202642..202959 (+)
• Length: 105 a.a.
• NCBI ID: WP_126466440.1
• Uniprot ID: A0A3Q9F2F9
• Organism: Streptococcus periodonticum strain KCOM 2412
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 197642..207959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EHW89_RS01015 (EHW89_01015)	-	197765..198295 (+)	531	WP_126466435.1	aromatic acid exporter family protein	-
EHW89_RS01020 (EHW89_01020)	-	198372..198731 (+)	360	WP_003028467.1	MerR family transcriptional regulator	-
EHW89_RS01025 (EHW89_01025)	glnA	198770..200116 (+)	1347	WP_126466436.1	type I glutamate--ammonia ligase	-
EHW89_RS01030 (EHW89_01030)	-	200305..200670 (+)	366	WP_126466437.1	DUF1033 family protein	-
EHW89_RS01035 (EHW89_01035)	comYA	200740..201681 (+)	942	WP_126466438.1	competence type IV pilus ATPase ComGA	Machinery gene
EHW89_RS01040 (EHW89_01040)	comYB	201623..202645 (+)	1023	WP_193552982.1	competence type IV pilus assembly protein ComGB	Machinery gene
EHW89_RS01045 (EHW89_01045)	comYC	202642..202959 (+)	318	WP_126466440.1	competence type IV pilus major pilin ComGC	Machinery gene
EHW89_RS01050 (EHW89_01050)	comYD	202919..203347 (+)	429	WP_003026995.1	competence type IV pilus minor pilin ComGD	Machinery gene
EHW89_RS01055 (EHW89_01055)	comGE/cglE	203319..203612 (+)	294	WP_003032294.1	competence type IV pilus minor pilin ComGE	Machinery gene
EHW89_RS01060 (EHW89_01060)	comGF/cglF	203596..204033 (+)	438	WP_003032293.1	competence type IV pilus minor pilin ComGF	Machinery gene
EHW89_RS01065 (EHW89_01065)	comGG	204014..204340 (+)	327	WP_018543596.1	competence type IV pilus minor pilin ComGG	-
EHW89_RS01070 (EHW89_01070)	comYH	204425..205378 (+)	954	WP_126466441.1	class I SAM-dependent methyltransferase	Machinery gene
EHW89_RS01075 (EHW89_01075)	-	205425..206624 (+)	1200	WP_126466442.1	acetate kinase	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11608.69 Da
• Isoelectric Point: 10.1006

>NTDB_id=331751 EHW89_RS01045 WP_126466440.1 202642..202959(+) (comYC) [Streptococcus periodonticum strain KCOM 2412]
MKKLKSLKVKGFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVNDGT
ITDKQAASYKAYYAKHTKEARSVAD

Nucleotide

• Length: 318 bp

>NTDB_id=331751 EHW89_RS01045 WP_126466440.1 202642..202959(+) (comYC) [Streptococcus periodonticum strain KCOM 2412]
ATGAAAAAATTAAAAAGTTTGAAGGTTAAAGGTTTTACTTTGGTAGAAATGTTAGTCGTGCTTCTTATCATCAGTGTTTT
GATGCTTTTGTTCGTGCCGAATTTGACTAAGCAAAAAGAAGCGGTGACGGAAAAAGGAAATGCAGCGGTGGTAAAAGTTG
TGGAAAGCCAGGCGGAGCTATTTGAGGTCAATCACACCAATGAAAAAGCGACACTCTCAAAATTAGTCAACGATGGCACG
ATTACAGACAAGCAGGCAGCATCTTATAAGGCTTACTATGCGAAACATACAAAAGAAGCTCGTTCTGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A3Q9F2F9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	73.333	100	0.733
comGC/cglC	Streptococcus mitis NCTC 12261	69.608	97.143	0.676
comGC/cglC	Streptococcus mitis SK321	69.608	97.143	0.676
comYC	Streptococcus mutans UA140	66.667	100	0.667
comYC	Streptococcus mutans UA159	66.667	100	0.667
comGC/cglC	Streptococcus pneumoniae R6	67.647	97.143	0.657
comGC/cglC	Streptococcus pneumoniae TIGR4	67.647	97.143	0.657
comGC/cglC	Streptococcus pneumoniae Rx1	67.647	97.143	0.657
comGC/cglC	Streptococcus pneumoniae D39	67.647	97.143	0.657
comYC	Streptococcus suis isolate S10	66.292	84.762	0.562
comGC	Lactococcus lactis subsp. cremoris KW2	54.808	99.048	0.543