Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   EHW89_RS01035 Genome accession   NZ_CP034543
Coordinates   200740..201681 (+) Length   313 a.a.
NCBI ID   WP_126466438.1    Uniprot ID   -
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 195740..206681
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS01010 (EHW89_01010) - 196051..197250 (+) 1200 WP_021001230.1 phosphoglycerate kinase -
  EHW89_RS01015 (EHW89_01015) - 197765..198295 (+) 531 WP_126466435.1 aromatic acid exporter family protein -
  EHW89_RS01020 (EHW89_01020) - 198372..198731 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  EHW89_RS01025 (EHW89_01025) glnA 198770..200116 (+) 1347 WP_126466436.1 type I glutamate--ammonia ligase -
  EHW89_RS01030 (EHW89_01030) - 200305..200670 (+) 366 WP_126466437.1 DUF1033 family protein -
  EHW89_RS01035 (EHW89_01035) comYA 200740..201681 (+) 942 WP_126466438.1 competence type IV pilus ATPase ComGA Machinery gene
  EHW89_RS01040 (EHW89_01040) comYB 201623..202645 (+) 1023 WP_193552982.1 competence type IV pilus assembly protein ComGB Machinery gene
  EHW89_RS01045 (EHW89_01045) comYC 202642..202959 (+) 318 WP_126466440.1 competence type IV pilus major pilin ComGC Machinery gene
  EHW89_RS01050 (EHW89_01050) comYD 202919..203347 (+) 429 WP_003026995.1 competence type IV pilus minor pilin ComGD Machinery gene
  EHW89_RS01055 (EHW89_01055) comGE/cglE 203319..203612 (+) 294 WP_003032294.1 competence type IV pilus minor pilin ComGE Machinery gene
  EHW89_RS01060 (EHW89_01060) comGF/cglF 203596..204033 (+) 438 WP_003032293.1 competence type IV pilus minor pilin ComGF Machinery gene
  EHW89_RS01065 (EHW89_01065) comGG 204014..204340 (+) 327 WP_018543596.1 competence type IV pilus minor pilin ComGG -
  EHW89_RS01070 (EHW89_01070) comYH 204425..205378 (+) 954 WP_126466441.1 class I SAM-dependent methyltransferase Machinery gene
  EHW89_RS01075 (EHW89_01075) - 205425..206624 (+) 1200 WP_126466442.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35826.03 Da        Isoelectric Point: 6.0583

>NTDB_id=331749 EHW89_RS01035 WP_126466438.1 200740..201681(+) (comYA) [Streptococcus periodonticum strain KCOM 2412]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFICNYEFEELAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YGDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFADQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKVVLQGICYQRLIAKGGIVDFVSEKYQEHEPIDWNRQIDQLHAAGHINLEQAEAEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=331749 EHW89_RS01035 WP_126466438.1 200740..201681(+) (comYA) [Streptococcus periodonticum strain KCOM 2412]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATATGCAATTATGAATTTGAAGAGCTAGCTGCTG
TAATCAGTCATTTCAAGTTTACTGCTGGGATGAATGTCGGCGAAAAACGTAGAAGCCAGTTAGGATCTTGTGATTATCAA
TATGGTGATAAGAAAACGTCATTACGACTATCAACAGTAGGGGATTATCGTGGATACGAAAGTCTGGTGATTCGTTTATT
GCATGATGAAGAGGCAGAGTTGAAGTTTTGGTTTGCTCAAATCCCAGAGTTAAAAGAACGCTTCAAACAACGAGGGCTTT
ATCTTTTTTCGGGACCGGTAGGAAGTGGTAAAACTACTCTTATGCACCAGTTGGCTCAAGAGCGTTTTGCCGATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCAGAGACAG
CAAGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCCGAGCTGAAAGTTGTCTTACAAGGGATTTGTTACCAACGCTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAGAAGTATCAAGAACACGAGCCAATCGATTGGAATAGGCAGATTGATCAGC
TTCATGCAGCAGGACATATCAATCTTGAGCAGGCAGAAGCGGAAAAAATTATCCACAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

83.226

99.042

0.824
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.399

100

0.754
  comYA Streptococcus mutans UA159

64.309

99.361

0.639
  comYA Streptococcus mutans UA140

64.309

99.361

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

44.697

84.345

0.377

Multiple sequence alignment