Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   EHW89_RS01040 Genome accession   NZ_CP034543
Coordinates   201623..202645 (+) Length   340 a.a.
NCBI ID   WP_193552982.1    Uniprot ID   -
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 196623..207645
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS01015 (EHW89_01015) - 197765..198295 (+) 531 WP_126466435.1 aromatic acid exporter family protein -
  EHW89_RS01020 (EHW89_01020) - 198372..198731 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  EHW89_RS01025 (EHW89_01025) glnA 198770..200116 (+) 1347 WP_126466436.1 type I glutamate--ammonia ligase -
  EHW89_RS01030 (EHW89_01030) - 200305..200670 (+) 366 WP_126466437.1 DUF1033 family protein -
  EHW89_RS01035 (EHW89_01035) comYA 200740..201681 (+) 942 WP_126466438.1 competence type IV pilus ATPase ComGA Machinery gene
  EHW89_RS01040 (EHW89_01040) comYB 201623..202645 (+) 1023 WP_193552982.1 competence type IV pilus assembly protein ComGB Machinery gene
  EHW89_RS01045 (EHW89_01045) comYC 202642..202959 (+) 318 WP_126466440.1 competence type IV pilus major pilin ComGC Machinery gene
  EHW89_RS01050 (EHW89_01050) comYD 202919..203347 (+) 429 WP_003026995.1 competence type IV pilus minor pilin ComGD Machinery gene
  EHW89_RS01055 (EHW89_01055) comGE/cglE 203319..203612 (+) 294 WP_003032294.1 competence type IV pilus minor pilin ComGE Machinery gene
  EHW89_RS01060 (EHW89_01060) comGF/cglF 203596..204033 (+) 438 WP_003032293.1 competence type IV pilus minor pilin ComGF Machinery gene
  EHW89_RS01065 (EHW89_01065) comGG 204014..204340 (+) 327 WP_018543596.1 competence type IV pilus minor pilin ComGG -
  EHW89_RS01070 (EHW89_01070) comYH 204425..205378 (+) 954 WP_126466441.1 class I SAM-dependent methyltransferase Machinery gene
  EHW89_RS01075 (EHW89_01075) - 205425..206624 (+) 1200 WP_126466442.1 acetate kinase -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 39127.17 Da        Isoelectric Point: 9.5230

>NTDB_id=331750 EHW89_RS01040 WP_193552982.1 201623..202645(+) (comYB) [Streptococcus periodonticum strain KCOM 2412]
MQQDISILSRQKRKKLSTVRQKKVVELLNNLFSSGFHLAEIIDFLKRSALLEEVYVDRMKEGLSTGKPFSDIMASLGFSD
NVVTQLSLAELHGNLSLSLSKIEEYLENVSKIKKKLVEVATYPFILFVFLIFIMLGLRNYLLPQLDRQNVATQIISNLPQ
LFLGSLGVVFVLFVIGFYWFQKSSKIAAFRLLARLPFFGTFIQTYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKYYPFFKKELGLIIEYGEVKSKLGCELEVYAQKTWETFFKRVHQAMNVIQPLAFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=331750 EHW89_RS01040 WP_193552982.1 201623..202645(+) (comYB) [Streptococcus periodonticum strain KCOM 2412]
ATGCAGCAGGACATATCAATCTTGAGCAGGCAGAAGCGGAAAAAATTATCCACAGTTAGGCAGAAAAAGGTCGTAGAGTT
GCTGAATAATCTTTTTTCTAGTGGCTTTCATTTGGCAGAAATTATCGACTTTTTGAAGCGAAGTGCCTTGTTAGAAGAAG
TCTATGTGGACAGGATGAAAGAGGGTTTGTCAACAGGAAAGCCTTTTTCGGACATTATGGCTAGTTTAGGTTTTTCAGAT
AATGTGGTAACACAACTTTCGCTGGCAGAATTACACGGAAATCTCTCACTCAGTCTGAGTAAGATTGAGGAATACTTGGA
AAATGTCTCAAAAATTAAGAAAAAGTTGGTTGAAGTGGCGACTTATCCCTTTATTTTGTTTGTTTTTTTGATATTCATTA
TGCTGGGATTACGTAATTATTTACTCCCGCAACTCGATCGTCAAAATGTAGCAACGCAGATTATCAGTAATTTGCCGCAA
CTTTTTCTGGGTTCATTAGGGGTAGTCTTTGTTTTGTTCGTGATAGGTTTTTATTGGTTTCAGAAAAGCTCCAAAATAGC
AGCATTTCGTTTGTTGGCTCGACTTCCTTTTTTTGGCACTTTTATTCAAACCTATTTGACAGCTTATTATGCGAGAGAAT
GGGGAAATATGATTGGTCAAGGTTTAGAACTCAGTCAGATTTTTCAGATGATGCAAGGGCAACGCTCTGCTATGTTTCAA
GAAATTGGAAAAGATTTAGAAGTTGCGCTGCAAAATGGCCAGGAATTTTCACAAGTAGTGAAATATTATCCATTTTTTAA
AAAGGAATTAGGCTTGATAATTGAATACGGTGAAGTGAAATCCAAATTGGGATGTGAATTAGAAGTTTATGCCCAAAAAA
CATGGGAGACATTTTTTAAACGTGTTCATCAAGCGATGAATGTTATTCAGCCACTAGCGTTTGTCTTTGTGGCCTTGATG
ATTGTATTGTTATATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

70.294

100

0.703
  comGB/cglB Streptococcus mitis NCTC 12261

67.761

98.529

0.668
  comGB/cglB Streptococcus mitis SK321

67.463

98.529

0.665
  comGB/cglB Streptococcus pneumoniae TIGR4

67.164

98.529

0.662
  comGB/cglB Streptococcus pneumoniae R6

67.164

98.529

0.662
  comGB/cglB Streptococcus pneumoniae Rx1

67.164

98.529

0.662
  comGB/cglB Streptococcus pneumoniae D39

67.164

98.529

0.662
  comYB Streptococcus mutans UA159

59.649

100

0.6
  comYB Streptococcus mutans UA140

59.357

100

0.597
  comGB Lactococcus lactis subsp. cremoris KW2

51.039

99.118

0.506

Multiple sequence alignment