Detailed information NTG0331755

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: EHW89_RS01070
• Genome accession: NZ_CP034543
• Coordinates: 204425..205378 (+)
• Length: 317 a.a.
• NCBI ID: WP_126466441.1
• Uniprot ID: A0A3S9MPN4
• Organism: Streptococcus periodonticum strain KCOM 2412
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 199425..210378

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EHW89_RS01030 (EHW89_01030)	-	200305..200670 (+)	366	WP_126466437.1	DUF1033 family protein	-
EHW89_RS01035 (EHW89_01035)	comYA	200740..201681 (+)	942	WP_126466438.1	competence type IV pilus ATPase ComGA	Machinery gene
EHW89_RS01040 (EHW89_01040)	comYB	201623..202645 (+)	1023	WP_193552982.1	competence type IV pilus assembly protein ComGB	Machinery gene
EHW89_RS01045 (EHW89_01045)	comYC	202642..202959 (+)	318	WP_126466440.1	competence type IV pilus major pilin ComGC	Machinery gene
EHW89_RS01050 (EHW89_01050)	comYD	202919..203347 (+)	429	WP_003026995.1	competence type IV pilus minor pilin ComGD	Machinery gene
EHW89_RS01055 (EHW89_01055)	comGE/cglE	203319..203612 (+)	294	WP_003032294.1	competence type IV pilus minor pilin ComGE	Machinery gene
EHW89_RS01060 (EHW89_01060)	comGF/cglF	203596..204033 (+)	438	WP_003032293.1	competence type IV pilus minor pilin ComGF	Machinery gene
EHW89_RS01065 (EHW89_01065)	comGG	204014..204340 (+)	327	WP_018543596.1	competence type IV pilus minor pilin ComGG	-
EHW89_RS01070 (EHW89_01070)	comYH	204425..205378 (+)	954	WP_126466441.1	class I SAM-dependent methyltransferase	Machinery gene
EHW89_RS01075 (EHW89_01075)	-	205425..206624 (+)	1200	WP_126466442.1	acetate kinase	-
EHW89_RS01080 (EHW89_01080)	glmS	207013..208827 (+)	1815	WP_126466443.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35913.79 Da
• Isoelectric Point: 4.3317

>NTDB_id=331755 EHW89_RS01070 WP_126466441.1 204425..205378(+) (comYH) [Streptococcus periodonticum strain KCOM 2412]
MNFEKIEQTYMLLLENVQEIQNDLLTSFYDALIEQNGSYLDGDIELDSVRQNNEKLKALKLSKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFILTFLIDQLSKKEHIDILEIGSGMGNLAETILNNTQKNMDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDSIAARYEVASTQDHTYAHHLLMEQSLKYLKSGGYAIFLAPNDLLTSSQ
SDLLKKWLQKHAQIVAMIALPESLFGNAAYAKTIFVLKKQDEQAVKPFVYALSDLQNQADLLTFSEKFQNWSQESEI

Nucleotide

• Length: 954 bp

>NTDB_id=331755 EHW89_RS01070 WP_126466441.1 204425..205378(+) (comYH) [Streptococcus periodonticum strain KCOM 2412]
ATGAATTTTGAAAAAATTGAACAGACCTATATGCTCTTGTTAGAAAATGTCCAAGAAATCCAAAATGATCTTTTAACGAG
CTTTTATGATGCTTTGATAGAGCAAAATGGCAGCTATCTGGACGGGGATATTGAACTAGATAGTGTTCGGCAGAACAATG
AAAAACTGAAAGCGTTGAAATTAAGTAAAGAGGAATGGCGCCGAGCCTACCAATTTTTGCTGATGAAAGCAGCTCAAACA
GAGCCTTTGCAAGCCAATCATCAATTTACTCCAGATTCTATCGGGTTTATCTTAACTTTTCTCATTGACCAATTGAGTAA
AAAAGAACACATTGATATTTTGGAAATTGGTAGCGGAATGGGGAATTTAGCAGAGACGATTCTCAATAATACACAAAAAA
ATATGGATTATCTAGGACTGGAATTGGACGATCTGCTAATTGATATATCAGCCAGTATCGCAGATGTGATGGATGCAAAA
GTTAGTTTTGTGCAAGGTGATGCAGTGCGTCCGCAAGTATTGAAAGAAAGCGATGTGATTATCAGTGATTTACCAGTTGG
CTTTTATCCTGATGATAGCATTGCGGCGCGCTATGAAGTGGCTAGTACACAGGATCATACCTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCAGGCGGTTATGCTATTTTCCTTGCACCAAATGATTTATTGACTAGTTCGCAA
AGTGATTTATTGAAGAAATGGCTACAAAAGCATGCACAAATAGTTGCAATGATTGCGTTACCAGAGTCTCTTTTTGGAAA
TGCAGCATACGCTAAAACAATTTTTGTACTGAAAAAGCAAGATGAACAAGCTGTCAAACCATTTGTTTATGCTTTATCTG
ATTTGCAGAATCAAGCGGATTTATTGACATTTAGCGAAAAGTTTCAAAATTGGAGCCAAGAAAGTGAAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-292)

3D structure

• AlphaFold DB: A0A3S9MPN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	61.587	99.369	0.612
comYH	Streptococcus mutans UA159	61.27	99.369	0.609