Detailed information NTG0317211

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: D7D53_RS08205
• Genome accession: NZ_CP032621
• Coordinates: 1626091..1626570 (-)
• Length: 159 a.a.
• NCBI ID: WP_120770660.1
• Uniprot ID: A0A387AZ31
• Organism: Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1621091..1631570

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D7D53_RS08205 (D7D53_08205)	comX/sigX/comX2/sigX2	1626091..1626570 (-)	480	WP_120770660.1	sigma-70 family RNA polymerase sigma factor	Regulator
D7D53_RS08210 (D7D53_08210)	nusG	1626691..1627227 (-)	537	WP_000376740.1	transcription termination/antitermination protein NusG	-
D7D53_RS08215 (D7D53_08215)	secE	1627281..1627457 (-)	177	WP_001210990.1	preprotein translocase subunit SecE	-
D7D53_RS08220 (D7D53_08220)	rpmG	1627467..1627619 (-)	153	WP_001809375.1	50S ribosomal protein L33	-
D7D53_RS08225 (D7D53_08225)	pbp2a	1627672..1629867 (-)	2196	WP_120770661.1	penicillin-binding protein PBP2A	-
D7D53_RS08230 (D7D53_08230)	-	1629954..1630829 (+)	876	WP_120770662.1	RluA family pseudouridine synthase	-

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 20029.69 Da
• Isoelectric Point: 7.4154

>NTDB_id=317211 D7D53_RS08205 WP_120770660.1 1626091..1626570(-) (comX/sigX/comX2/sigX2) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MFKELYKEVQGIVYKSRNEYYLHLWELSDWDQEGMICLHELISREEELVEDIPRLRKYFKTKFQNRILDYIRKQESQKRR
YDKEPYEEVGELSHRISEGGLWLDDYYLFHETLRDYRNKQSKDKQEELERVLRNERFRGRQRVLRDLRIVFKEFDIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=317211 D7D53_RS08205 WP_120770660.1 1626091..1626570(-) (comX/sigX/comX2/sigX2) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGTTTAAAGAATTGTATAAAGAAGTCCAGGGAATTGTATATAAAAGTAGAAATGAATATTACCTTCATTTATGGGAGCT
ATCGGATTGGGACCAAGAGGGAATGATTTGCTTGCATGAATTGATCAGTAGAGAAGAAGAGCTAGTAGAAGATATTCCTC
GTTTAAGGAAATATTTTAAGACTAAGTTCCAGAATCGAATTCTAGACTATATCCGTAAGCAAGAAAGTCAAAAACGAAGA
TATGATAAAGAACCTTATGAAGAAGTAGGTGAGCTCAGTCATCGTATCAGTGAGGGCGGTCTGTGGCTAGATGACTATTA
TCTCTTTCATGAGACACTAAGAGATTATAGAAACAAACAAAGTAAAGATAAACAAGAAGAGTTAGAACGTGTCTTAAGAA
ACGAACGCTTCCGAGGTCGTCAAAGAGTATTAAGAGACTTACGTATTGTGTTTAAAGAGTTTGACATCCGTACTCATTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A387AZ31

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	96.203	99.371	0.956
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	94.969	100	0.95
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	93.711	100	0.937
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	94.304	99.371	0.937
comX/comX2	Streptococcus pneumoniae R6	92.453	100	0.925
comX/comX1	Streptococcus pneumoniae R6	92.453	100	0.925
comX/comX2	Streptococcus pneumoniae D39	92.453	100	0.925
comX/comX2	Streptococcus pneumoniae Rx1	92.453	100	0.925
comX/comX1	Streptococcus pneumoniae Rx1	92.453	100	0.925
comX/comX1	Streptococcus pneumoniae D39	92.453	100	0.925
comX/comX2	Streptococcus pneumoniae TIGR4	91.824	100	0.918
comX/comX1	Streptococcus pneumoniae TIGR4	91.824	100	0.918
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comX/sigX	Streptococcus suis isolate S10	45.752	96.226	0.44
comX/sigX	Streptococcus suis D9	45.752	96.226	0.44
comX/sigX	Streptococcus suis P1/7	45.752	96.226	0.44
comX/sigX	Streptococcus mutans UA159	45.752	96.226	0.44
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.953	93.711	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.953	93.711	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.953	93.711	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.953	93.711	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.105	95.597	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.105	95.597	0.403
comX	Streptococcus sobrinus strain NIDR 6715-7	37.662	96.855	0.365