Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   D7D50_RS02045 Genome accession   NZ_CP032620
Coordinates   383301..384260 (-) Length   319 a.a.
NCBI ID   WP_120701356.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 378301..389260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS02005 (D7D50_02005) - 378310..379506 (-) 1197 WP_120701350.1 acetate kinase -
  D7D50_RS02010 (D7D50_02010) comYH 379555..380508 (-) 954 WP_120701351.1 class I SAM-dependent methyltransferase Machinery gene
  D7D50_RS02015 (D7D50_02015) comGG 380540..380923 (-) 384 WP_418856565.1 competence type IV pilus minor pilin ComGG -
  D7D50_RS02020 (D7D50_02020) comGF/cglF 380952..381404 (-) 453 WP_162614527.1 competence type IV pilus minor pilin ComGF Machinery gene
  D7D50_RS02025 (D7D50_02025) comGE 381388..381681 (-) 294 WP_120701354.1 competence type IV pilus minor pilin ComGE -
  D7D50_RS02030 (D7D50_02030) comGD/cglD 381647..382051 (-) 405 WP_120702309.1 competence type IV pilus minor pilin ComGD Machinery gene
  D7D50_RS02035 (D7D50_02035) comGC/cglC 382041..382358 (-) 318 WP_023027561.1 competence type IV pilus major pilin ComGC Machinery gene
  D7D50_RS02040 (D7D50_02040) comYB 382355..383377 (-) 1023 WP_120701355.1 competence type IV pilus assembly protein ComGB Machinery gene
  D7D50_RS02045 (D7D50_02045) comYA 383301..384260 (-) 960 WP_120701356.1 competence type IV pilus ATPase ComGA Machinery gene
  D7D50_RS02050 (D7D50_02050) - 384365..384742 (-) 378 WP_120701357.1 DUF1033 family protein -
  D7D50_RS02060 (D7D50_02060) - 385102..386205 (-) 1104 WP_120701358.1 glycosyl hydrolase family 8 -
  D7D50_RS02065 (D7D50_02065) - 386214..387524 (-) 1311 WP_120701359.1 glycosyltransferase family 2 protein -
  D7D50_RS10130 (D7D50_02070) - 387517..387657 (-) 141 WP_006595142.1 hypothetical protein -
  D7D50_RS02075 (D7D50_02075) - 387667..388455 (-) 789 WP_120701360.1 hypothetical protein -

Sequence

Protein


Download         Length: 319 a.a.        Molecular weight: 36340.57 Da        Isoelectric Point: 5.8892

>NTDB_id=317125 D7D50_RS02045 WP_120701356.1 383301..384260(-) (comYA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MVQEIAQSIIRMASSAEAQDIYFVPRASDYQLFLRVGDERRFIETYSQEQMVAIISHFKFMAGMNVGERRRSQLGSCDYS
LGDKVLSLRLSTVGDYRGYESLVIRLLHNEDRELRFWFDQLQELEEKVSKRGLYLFAGPVGSGKTTLMHALAKKKFSGQQ
VMSIEDPVEIKQEEMLQLQLNEAIGMTYDSLIKLSLRHRPDLLLIGEIRDTETARAVIRASLTGVTVFSTIHAKSIPGVY
ERLLELGVSEEELRIVLQGICYQRLIKGGGVTDFVIQDYQNHSSQKWNQQIDALYEAGHIELDQAQAEKIIDCQARACH

Nucleotide


Download         Length: 960 bp        

>NTDB_id=317125 D7D50_RS02045 WP_120701356.1 383301..384260(-) (comYA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGGTTCAAGAAATTGCACAATCCATTATTCGAATGGCCTCGAGTGCCGAAGCTCAGGATATTTATTTTGTTCCTCGAGC
GTCAGACTATCAGCTCTTTCTAAGGGTTGGGGATGAGCGACGGTTTATTGAGACTTATTCGCAAGAACAAATGGTAGCGA
TCATCAGCCATTTTAAATTTATGGCAGGGATGAACGTGGGGGAGAGGCGGAGGAGTCAGTTAGGCTCCTGTGACTATTCT
CTAGGAGATAAGGTCCTGTCCTTACGCTTGTCCACAGTGGGGGACTATAGGGGATATGAAAGTTTGGTCATTCGCCTGCT
CCACAATGAGGACCGGGAGCTCCGTTTCTGGTTTGACCAACTGCAAGAGCTAGAAGAGAAGGTGAGTAAGCGGGGGCTCT
ACTTATTTGCGGGTCCAGTCGGATCGGGGAAGACGACACTGATGCATGCCCTAGCCAAGAAAAAATTTTCGGGGCAACAA
GTCATGTCGATTGAAGATCCGGTAGAAATTAAGCAAGAAGAAATGTTGCAATTGCAACTCAATGAAGCGATTGGCATGAC
CTATGATAGCTTGATTAAACTTTCTCTGCGCCATCGTCCGGATCTTCTCCTCATCGGAGAAATACGCGACACGGAGACAG
CTCGTGCAGTTATTCGGGCTAGTCTGACAGGTGTGACAGTCTTTTCCACCATCCATGCCAAGAGCATCCCTGGGGTGTAC
GAACGCCTATTGGAGTTGGGGGTGAGTGAGGAGGAGTTACGGATTGTCCTTCAAGGGATCTGTTACCAGCGTTTGATAAA
GGGAGGAGGTGTCACTGACTTTGTCATCCAAGATTACCAAAACCATTCCAGTCAAAAGTGGAACCAGCAAATTGATGCAC
TTTATGAAGCGGGACATATTGAGTTGGATCAGGCGCAGGCCGAAAAAATTATCGATTGCCAAGCAAGAGCATGTCATTGA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

74.295

100

0.743
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

72.903

97.179

0.708
  comGA/cglA/cilD Streptococcus pneumoniae D39

72.258

97.179

0.702
  comGA/cglA/cilD Streptococcus pneumoniae R6

72.258

97.179

0.702
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

72.258

97.179

0.702
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

72.258

97.179

0.702
  comYA Streptococcus mutans UA159

65.176

98.119

0.64
  comYA Streptococcus mutans UA140

65.176

98.119

0.64
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.5

97.806

0.611
  comGA Lactococcus lactis subsp. cremoris KW2

55.696

99.06

0.552
  comGA Latilactobacillus sakei subsp. sakei 23K

41.877

86.834

0.364

Multiple sequence alignment