Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   D7D50_RS02040 Genome accession   NZ_CP032620
Coordinates   382355..383377 (-) Length   340 a.a.
NCBI ID   WP_120701355.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 377355..388377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS02000 (D7D50_02000) - 377483..378157 (-) 675 WP_227877753.1 CPBP family intramembrane glutamic endopeptidase -
  D7D50_RS02005 (D7D50_02005) - 378310..379506 (-) 1197 WP_120701350.1 acetate kinase -
  D7D50_RS02010 (D7D50_02010) comYH 379555..380508 (-) 954 WP_120701351.1 class I SAM-dependent methyltransferase Machinery gene
  D7D50_RS02015 (D7D50_02015) comGG 380540..380923 (-) 384 WP_418856565.1 competence type IV pilus minor pilin ComGG -
  D7D50_RS02020 (D7D50_02020) comGF/cglF 380952..381404 (-) 453 WP_162614527.1 competence type IV pilus minor pilin ComGF Machinery gene
  D7D50_RS02025 (D7D50_02025) comGE 381388..381681 (-) 294 WP_120701354.1 competence type IV pilus minor pilin ComGE -
  D7D50_RS02030 (D7D50_02030) comGD/cglD 381647..382051 (-) 405 WP_120702309.1 competence type IV pilus minor pilin ComGD Machinery gene
  D7D50_RS02035 (D7D50_02035) comGC/cglC 382041..382358 (-) 318 WP_023027561.1 competence type IV pilus major pilin ComGC Machinery gene
  D7D50_RS02040 (D7D50_02040) comYB 382355..383377 (-) 1023 WP_120701355.1 competence type IV pilus assembly protein ComGB Machinery gene
  D7D50_RS02045 (D7D50_02045) comYA 383301..384260 (-) 960 WP_120701356.1 competence type IV pilus ATPase ComGA Machinery gene
  D7D50_RS02050 (D7D50_02050) - 384365..384742 (-) 378 WP_120701357.1 DUF1033 family protein -
  D7D50_RS02060 (D7D50_02060) - 385102..386205 (-) 1104 WP_120701358.1 glycosyl hydrolase family 8 -
  D7D50_RS02065 (D7D50_02065) - 386214..387524 (-) 1311 WP_120701359.1 glycosyltransferase family 2 protein -
  D7D50_RS10130 (D7D50_02070) - 387517..387657 (-) 141 WP_006595142.1 hypothetical protein -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 38857.91 Da        Isoelectric Point: 9.7545

>NTDB_id=317124 D7D50_RS02040 WP_120701355.1 382355..383377(-) (comYB) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MKRDILSWIRRRPKKLSIAKQEHVIELFHNLYSSGFHLSEVIDFLRRSHLVEADFVERMQVGLANGKPLSAILSDLGFSD
QVTTQLALAEQHGNVTLSLEKIRSYLENLTQVRKKLVEVATYPVLLLGFLMFIMLGLKNYLLPQLESQNGATRLISVFPQ
YVLLGSVLLAIGVLILLFLGRRAKRLALVSFLATLPFLRPFLQDYLTAFYAREWGSMIAQGLELNQIFPMMQGQRSRLFR
EIGQDLEVALARGTSFSEHIQTYPFFKRELALMIEYGEAKSKLGSELEIYADKTWAGFFHRLNKAMNVVQPLVFVFVALM
IVLLYAAMLLPIYENLEVPL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=317124 D7D50_RS02040 WP_120701355.1 382355..383377(-) (comYB) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGAAGCGGGACATATTGAGTTGGATCAGGCGCAGGCCGAAAAAATTATCGATTGCCAAGCAAGAGCATGTCATTGAGCT
CTTTCACAATCTCTACAGTAGTGGCTTTCATCTATCAGAGGTCATCGACTTCCTACGTCGGAGCCATTTGGTAGAGGCAG
ATTTTGTTGAAAGAATGCAAGTTGGACTTGCCAACGGCAAGCCCCTGTCAGCCATTCTTTCTGATCTAGGCTTTTCCGAT
CAAGTAACGACTCAATTAGCACTGGCAGAGCAGCATGGAAATGTCACCTTAAGTTTAGAAAAAATCCGTAGCTACCTGGA
AAATCTGACCCAGGTTCGAAAGAAACTAGTTGAGGTGGCCACCTATCCAGTACTATTGTTGGGATTTTTGATGTTCATTA
TGCTGGGTCTGAAAAACTATCTCTTGCCTCAGTTGGAGAGTCAAAATGGTGCGACACGATTGATCAGTGTCTTTCCACAG
TATGTTTTGTTAGGAAGTGTGTTACTAGCAATTGGAGTTTTGATTCTCCTCTTCCTAGGTCGTCGAGCCAAGCGTCTGGC
CCTTGTTTCGTTTTTGGCTACCCTTCCTTTTCTTCGCCCCTTCTTACAGGATTATCTGACGGCTTTTTATGCTCGAGAAT
GGGGGAGTATGATTGCCCAAGGGTTGGAGCTGAATCAAATCTTTCCTATGATGCAGGGGCAACGTTCCCGTCTGTTTCGT
GAGATTGGACAGGATTTGGAAGTAGCATTGGCTCGGGGGACTTCTTTTTCTGAACATATTCAGACCTATCCTTTCTTTAA
GCGAGAGTTGGCCCTCATGATTGAATATGGAGAGGCCAAGTCCAAGCTCGGTAGTGAGCTGGAGATCTACGCAGACAAGA
CCTGGGCAGGCTTTTTCCATCGTTTGAACAAGGCTATGAATGTCGTCCAACCACTGGTCTTTGTCTTTGTCGCCCTTATG
ATTGTTTTGCTCTATGCAGCCATGTTGCTGCCTATTTATGAAAATTTGGAGGTTCCTTTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

61.111

100

0.615
  comGB/cglB Streptococcus mitis NCTC 12261

59.821

98.824

0.591
  comGB/cglB Streptococcus pneumoniae Rx1

59.524

98.824

0.588
  comGB/cglB Streptococcus pneumoniae D39

59.524

98.824

0.588
  comGB/cglB Streptococcus pneumoniae R6

59.524

98.824

0.588
  comGB/cglB Streptococcus pneumoniae TIGR4

59.524

98.824

0.588
  comGB/cglB Streptococcus mitis SK321

59.226

98.824

0.585
  comYB Streptococcus mutans UA140

60.252

93.235

0.562
  comYB Streptococcus mutans UA159

60.252

93.235

0.562
  comGB Lactococcus lactis subsp. cremoris KW2

48.397

100

0.488

Multiple sequence alignment