Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   SEZ_RS00735 Genome accession   NC_011134
Coordinates   130272..130595 (+) Length   107 a.a.
NCBI ID   WP_012514782.1    Uniprot ID   B4U056
Organism   Streptococcus equi subsp. zooepidemicus MGCS10565     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 125272..135595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEZ_RS09570 - 125279..125470 (+) 192 Protein_110 lactococcin 972 family bacteriocin -
  SEZ_RS00715 (Sez_0113) - 125535..127538 (+) 2004 WP_012514778.1 DUF1430 domain-containing protein -
  SEZ_RS00720 (Sez_0114) - 127540..128208 (+) 669 WP_012514779.1 ATP-binding cassette domain-containing protein -
  SEZ_RS00725 (Sez_0115) comGA/cglA 128366..129304 (+) 939 WP_012514780.1 competence type IV pilus ATPase ComGA Machinery gene
  SEZ_RS00730 (Sez_0116) comYB 129237..130271 (+) 1035 WP_228275455.1 competence type IV pilus assembly protein ComGB Machinery gene
  SEZ_RS00735 (Sez_0117) comGC/cglC 130272..130595 (+) 324 WP_012514782.1 competence type IV pilus major pilin ComGC Machinery gene
  SEZ_RS00740 (Sez_0118) comGD 130573..130998 (+) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  SEZ_RS00745 comGE 130955..131246 (+) 292 Protein_117 competence type IV pilus minor pilin ComGE -
  SEZ_RS00750 (Sez_0119) comYF 131233..131667 (+) 435 WP_037580631.1 competence type IV pilus minor pilin ComGF Machinery gene
  SEZ_RS00755 (Sez_0120) comGG 131645..132007 (+) 363 WP_012514785.1 competence type IV pilus minor pilin ComGG -
  SEZ_RS00770 (Sez_0123) comYH 133501..134454 (+) 954 WP_012514788.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 12149.19 Da        Isoelectric Point: 8.4057

>NTDB_id=31352 SEZ_RS00735 WP_012514782.1 130272..130595(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE
DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide


Download         Length: 324 bp        

>NTDB_id=31352 SEZ_RS00735 WP_012514782.1 130272..130595(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus MGCS10565]
ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTATTAAT
CATTAGTGTTTTAATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCAG
TGGTAAAGCTAGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG
GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA
TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4U056

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

59.813

100

0.598
  comGC/cglC Streptococcus pneumoniae Rx1

57.944

100

0.579
  comGC/cglC Streptococcus pneumoniae D39

57.944

100

0.579
  comGC/cglC Streptococcus pneumoniae R6

57.944

100

0.579
  comGC/cglC Streptococcus pneumoniae TIGR4

57.944

100

0.579
  comYC Streptococcus gordonii str. Challis substr. CH1

62.245

91.589

0.57
  comGC/cglC Streptococcus mitis NCTC 12261

61.616

92.523

0.57
  comYC Streptococcus mutans UA140

58.763

90.654

0.533
  comYC Streptococcus mutans UA159

58.763

90.654

0.533
  comGC Lactococcus lactis subsp. cremoris KW2

56.842

88.785

0.505
  comYC Streptococcus suis isolate S10

60

74.766

0.449
  comGC Staphylococcus aureus MW2

50

72.897

0.364
  comGC Staphylococcus aureus N315

50

72.897

0.364

Multiple sequence alignment