Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DDV21_RS00755 Genome accession   NZ_CP031733
Coordinates   122820..123761 (+) Length   313 a.a.
NCBI ID   WP_116878371.1    Uniprot ID   A0A372KL41
Organism   Streptococcus chenjunshii strain Z15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 117820..128761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS00745 (DDV21_000745) - 121334..121963 (-) 630 WP_116878372.1 hypothetical protein -
  DDV21_RS00750 (DDV21_000750) - 122393..122755 (+) 363 WP_116878385.1 DUF1033 family protein -
  DDV21_RS00755 (DDV21_000755) comYA 122820..123761 (+) 942 WP_116878371.1 competence type IV pilus ATPase ComGA Machinery gene
  DDV21_RS00760 (DDV21_000760) comYB 123667..124728 (+) 1062 WP_116878370.1 competence type IV pilus assembly protein ComGB Machinery gene
  DDV21_RS00765 (DDV21_000765) comYC 124729..125055 (+) 327 WP_116878369.1 competence type IV pilus major pilin ComGC Machinery gene
  DDV21_RS00770 (DDV21_000770) comYD 125006..125461 (+) 456 WP_259293365.1 competence type IV pilus minor pilin ComGD Machinery gene
  DDV21_RS00775 (DDV21_000775) comGE 125415..125708 (+) 294 WP_116878368.1 competence type IV pilus minor pilin ComGE -
  DDV21_RS00780 (DDV21_000780) comYF 125662..126120 (+) 459 WP_116878367.1 competence type IV pilus minor pilin ComGF Machinery gene
  DDV21_RS00785 (DDV21_000785) comGG 126107..126484 (+) 378 WP_116878366.1 competence type IV pilus minor pilin ComGG -
  DDV21_RS00790 (DDV21_000790) comYH 126990..127946 (+) 957 WP_116878383.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35318.57 Da        Isoelectric Point: 7.4368

>NTDB_id=310810 DDV21_RS00755 WP_116878371.1 122820..123761(+) (comYA) [Streptococcus chenjunshii strain Z15]
MVQDLAKTIIKEAVSVNAQDIYMIPKGERYELYIRVGAERKKLDCFEPSHMFSIISHFKFVAGMNVGEKRRSQLGSCDYV
FGEGKEISLRLSSVGDYRGRESLVIRLLYPGIYRTNYWFDNLERLQTNVGSRGLYLFSGPVGSGKTTLMYQLATEKFQNK
QIISIEDPVEIKDETMLQLQINESIGMTYDHLIKLSLRHRPDILIVGEIRDETTAHAAIRASLTGIVVFSTIHAKSIAGV
YDRLEELGVSQGELSSCLQLIAYQRLIGGGGVIDFAAENFQNHVPDSWNKQIDRLVKGGYITKEEARLEKIKA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=310810 DDV21_RS00755 WP_116878371.1 122820..123761(+) (comYA) [Streptococcus chenjunshii strain Z15]
ATGGTTCAGGATTTAGCAAAGACGATTATAAAAGAGGCTGTATCAGTTAATGCTCAGGACATTTATATGATTCCTAAAGG
GGAACGCTATGAATTATATATACGTGTTGGAGCTGAAAGAAAGAAGCTTGATTGCTTTGAGCCTTCTCATATGTTTAGTA
TCATTAGTCACTTTAAATTTGTAGCAGGGATGAATGTTGGTGAGAAACGTCGCAGCCAGTTAGGATCTTGCGATTATGTT
TTCGGTGAAGGAAAGGAAATTTCTCTGCGTTTATCAAGTGTTGGCGACTACCGGGGACGGGAAAGTTTAGTGATTCGACT
GCTTTATCCTGGAATTTATCGCACAAACTACTGGTTTGATAATCTGGAGCGGTTGCAGACCAATGTTGGCAGCCGAGGCC
TCTACCTTTTTTCGGGACCGGTTGGTTCTGGGAAGACCACTCTCATGTACCAGCTGGCAACTGAGAAGTTCCAAAATAAG
CAGATTATTTCCATTGAAGATCCTGTCGAAATCAAAGATGAAACGATGCTGCAACTGCAAATCAACGAAAGTATTGGTAT
GACTTATGATCATTTAATTAAGCTCTCGCTCCGCCATCGTCCGGATATTCTTATTGTTGGTGAAATCCGTGACGAGACAA
CAGCTCATGCTGCTATTCGTGCCAGTTTAACCGGCATTGTTGTTTTTTCTACGATTCATGCCAAAAGTATTGCTGGGGTT
TATGACCGCCTAGAGGAGTTGGGAGTCAGTCAAGGAGAGCTAAGCAGCTGTTTACAGTTAATTGCTTATCAGCGTCTAAT
CGGAGGGGGAGGAGTCATTGATTTTGCTGCTGAAAATTTTCAAAACCATGTCCCGGACAGTTGGAATAAACAAATTGATA
GGCTTGTTAAGGGTGGATATATTACCAAAGAAGAAGCGAGGCTTGAGAAAATTAAGGCTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KL41

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

66.026

99.681

0.658
  comYA Streptococcus mutans UA140

66.026

99.681

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

63.666

99.361

0.633
  comYA Streptococcus gordonii str. Challis substr. CH1

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.379

99.361

0.62
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.093

99.361

0.607
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.093

99.361

0.607
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.093

99.361

0.607
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.093

99.361

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514

Multiple sequence alignment