Detailed information NTG0310814

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DDV21_RS00780
• Genome accession: NZ_CP031733
• Coordinates: 125662..126120 (+)
• Length: 152 a.a.
• NCBI ID: WP_116878367.1
• Uniprot ID: A0A372KL49
• Organism: Streptococcus chenjunshii strain Z15
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 120662..131120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DDV21_RS00745 (DDV21_000745)	-	121334..121963 (-)	630	WP_116878372.1	hypothetical protein	-
DDV21_RS00750 (DDV21_000750)	-	122393..122755 (+)	363	WP_116878385.1	DUF1033 family protein	-
DDV21_RS00755 (DDV21_000755)	comYA	122820..123761 (+)	942	WP_116878371.1	competence type IV pilus ATPase ComGA	Machinery gene
DDV21_RS00760 (DDV21_000760)	comYB	123667..124728 (+)	1062	WP_116878370.1	competence type IV pilus assembly protein ComGB	Machinery gene
DDV21_RS00765 (DDV21_000765)	comYC	124729..125055 (+)	327	WP_116878369.1	competence type IV pilus major pilin ComGC	Machinery gene
DDV21_RS00770 (DDV21_000770)	comYD	125006..125461 (+)	456	WP_259293365.1	competence type IV pilus minor pilin ComGD	Machinery gene
DDV21_RS00775 (DDV21_000775)	comGE	125415..125708 (+)	294	WP_116878368.1	competence type IV pilus minor pilin ComGE	-
DDV21_RS00780 (DDV21_000780)	comYF	125662..126120 (+)	459	WP_116878367.1	competence type IV pilus minor pilin ComGF	Machinery gene
DDV21_RS00785 (DDV21_000785)	comGG	126107..126484 (+)	378	WP_116878366.1	competence type IV pilus minor pilin ComGG	-
DDV21_RS00790 (DDV21_000790)	comYH	126990..127946 (+)	957	WP_116878383.1	class I SAM-dependent methyltransferase	Machinery gene
DDV21_RS00795 (DDV21_000795)	-	127998..129191 (+)	1194	WP_116878365.1	acetate kinase	-
DDV21_RS11695	-	129323..129478 (-)	156	WP_162886265.1	hypothetical protein	-
DDV21_RS00800 (DDV21_000800)	-	129488..129928 (-)	441	WP_116878364.1	pyridoxamine 5'-phosphate oxidase family protein	-
DDV21_RS00805 (DDV21_000805)	proC	130176..130946 (-)	771	WP_116878363.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 152 a.a.
• Molecular weight: 17334.99 Da
• Isoelectric Point: 9.8321

>NTDB_id=310814 DDV21_RS00780 WP_116878367.1 125662..126120(+) (comYF) [Streptococcus chenjunshii strain Z15]
MSMKMNKKFCVLKNFRVRSFTLLECIIALFVISGSVLVYEALTASLSTNIRYLSDNYQENWLLFSQQLHTELAGSQLEKV
EGNKLYISRDGQQLALGQSKADDFRKTNADGRGYQPMLFGLADSHISRESNIVTIRLTFKNGLKRSFIYAFT

Nucleotide

• Length: 459 bp

>NTDB_id=310814 DDV21_RS00780 WP_116878367.1 125662..126120(+) (comYF) [Streptococcus chenjunshii strain Z15]
ATGTCTATGAAAATGAACAAGAAATTCTGCGTGCTGAAAAATTTTAGAGTTCGGAGTTTTACCCTTTTAGAGTGTATTAT
AGCCCTTTTTGTGATATCAGGATCTGTTCTTGTCTATGAGGCTTTGACAGCATCATTAAGTACTAATATCCGCTATCTAT
CTGATAATTATCAAGAAAACTGGCTTCTGTTTTCGCAGCAGTTGCATACAGAGTTGGCTGGGAGCCAATTAGAGAAAGTT
GAAGGCAACAAGCTTTATATAAGCAGGGATGGGCAGCAACTAGCTCTAGGGCAATCTAAAGCAGACGATTTTCGGAAGAC
AAATGCTGATGGACGCGGTTACCAGCCGATGCTATTCGGATTAGCTGACAGCCATATCAGCCGAGAAAGCAATATAGTAA
CAATAAGACTGACCTTTAAAAATGGTTTGAAAAGGAGTTTTATTTATGCTTTTACATAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (50-144)

3D structure

• AlphaFold DB: A0A372KL49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA159	55.147	89.474	0.493
comYF	Streptococcus mutans UA140	54.412	89.474	0.487
comGF/cglF	Streptococcus mitis NCTC 12261	50.355	92.763	0.467
comGF/cglF	Streptococcus pneumoniae TIGR4	50.365	90.132	0.454
comGF/cglF	Streptococcus pneumoniae R6	50.365	90.132	0.454
comGF/cglF	Streptococcus pneumoniae Rx1	50.365	90.132	0.454
comGF/cglF	Streptococcus pneumoniae D39	50.365	90.132	0.454
comGF/cglF	Streptococcus mitis SK321	48.936	92.763	0.454
comGF	Lactococcus lactis subsp. cremoris KW2	42.029	90.789	0.382