Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   DV119_RS01875 Genome accession   NZ_CP031245
Coordinates   310992..311933 (-) Length   313 a.a.
NCBI ID   WP_000249549.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M16808     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 305992..316933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV119_RS01835 comYH 306478..307431 (-) 954 WP_050308921.1 class I SAM-dependent methyltransferase Machinery gene
  DV119_RS01840 - 307492..308086 (-) 595 Protein_314 class I SAM-dependent methyltransferase -
  DV119_RS01845 comGG/cglG 308223..308636 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  DV119_RS01850 comGF/cglF 308614..309075 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  DV119_RS01855 comGE/cglE 309038..309340 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  DV119_RS01860 comGD/cglD 309303..309707 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  DV119_RS01865 comGC/cglC 309700..310026 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  DV119_RS01870 comGB/cglB 310028..311044 (-) 1017 WP_114880773.1 competence type IV pilus assembly protein ComGB Machinery gene
  DV119_RS01875 comGA/cglA/cilD 310992..311933 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  DV119_RS01880 - 312009..312374 (-) 366 WP_000286415.1 DUF1033 family protein -
  DV119_RS01885 - 312525..313583 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  DV119_RS01890 nagA 313746..314897 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  DV119_RS01895 - 315050..316867 (-) 1818 WP_001220922.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35543.45 Da        Isoelectric Point: 6.0083

>NTDB_id=304614 DV119_RS01875 WP_000249549.1 310992..311933(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain M16808]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=304614 DV119_RS01875 WP_000249549.1 310992..311933(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain M16808]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCTAAGTT
AGATGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae D39

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae R6

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

99.042

100

0.99
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.805

100

0.968
  comYA Streptococcus gordonii str. Challis substr. CH1

78.065

99.042

0.773
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.912

86.901

0.364

Multiple sequence alignment