Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ECE110019_RS21140 Genome accession   NZ_CP035751
Coordinates   4242832..4243464 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli E110019     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4237832..4248464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECE110019_RS21115 yheS 4238001..4239914 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  ECE110019_RS21120 yheT 4239914..4240936 (+) 1023 WP_000057405.1 hydrolase -
  ECE110019_RS21125 yheU 4240930..4241148 (+) 219 WP_000907085.1 YheU family protein -
  ECE110019_RS21130 prkB 4241202..4242071 (+) 870 WP_001274694.1 phosphoribulokinase -
  ECE110019_RS21135 yhfA 4242126..4242530 (-) 405 WP_001148908.1 OsmC family protein -
  ECE110019_RS21140 crp 4242832..4243464 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  ECE110019_RS21145 yhfK 4243515..4245605 (+) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  ECE110019_RS21150 argD 4245672..4246892 (-) 1221 WP_000963798.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  ECE110019_RS21155 pabA 4246978..4247541 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  ECE110019_RS21160 fic 4247573..4248175 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  ECE110019_RS21165 yhfG 4248165..4248332 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=304607 ECE110019_RS21140 WP_000242755.1 4242832..4243464(+) (crp) [Escherichia coli E110019]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=304607 ECE110019_RS21140 WP_000242755.1 4242832..4243464(+) (crp) [Escherichia coli E110019]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment