Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DV119_RS01855 Genome accession   NZ_CP031245
Coordinates   309038..309340 (-) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M16808     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 304038..314340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV119_RS01825 rnpA 304717..305088 (-) 372 WP_000739246.1 ribonuclease P protein component -
  DV119_RS11985 - 305105..305236 (-) 132 WP_000768904.1 hypothetical protein -
  DV119_RS01830 - 305237..306427 (-) 1191 WP_000167766.1 acetate kinase -
  DV119_RS01835 comYH 306478..307431 (-) 954 WP_050308921.1 class I SAM-dependent methyltransferase Machinery gene
  DV119_RS01840 - 307492..308086 (-) 595 Protein_314 class I SAM-dependent methyltransferase -
  DV119_RS01845 comGG/cglG 308223..308636 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  DV119_RS01850 comGF/cglF 308614..309075 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  DV119_RS01855 comGE/cglE 309038..309340 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  DV119_RS01860 comGD/cglD 309303..309707 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  DV119_RS01865 comGC/cglC 309700..310026 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  DV119_RS01870 comGB/cglB 310028..311044 (-) 1017 WP_114880773.1 competence type IV pilus assembly protein ComGB Machinery gene
  DV119_RS01875 comGA/cglA/cilD 310992..311933 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  DV119_RS01880 - 312009..312374 (-) 366 WP_000286415.1 DUF1033 family protein -
  DV119_RS01885 - 312525..313583 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=304610 DV119_RS01855 WP_000413380.1 309038..309340(-) (comGE/cglE) [Streptococcus pneumoniae strain M16808]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=304610 DV119_RS01855 WP_000413380.1 309038..309340(-) (comGE/cglE) [Streptococcus pneumoniae strain M16808]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment