Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   DV119_RS01870 Genome accession   NZ_CP031245
Coordinates   310028..311044 (-) Length   338 a.a.
NCBI ID   WP_114880773.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M16808     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 305028..316044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV119_RS11985 - 305105..305236 (-) 132 WP_000768904.1 hypothetical protein -
  DV119_RS01830 - 305237..306427 (-) 1191 WP_000167766.1 acetate kinase -
  DV119_RS01835 comYH 306478..307431 (-) 954 WP_050308921.1 class I SAM-dependent methyltransferase Machinery gene
  DV119_RS01840 - 307492..308086 (-) 595 Protein_314 class I SAM-dependent methyltransferase -
  DV119_RS01845 comGG/cglG 308223..308636 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  DV119_RS01850 comGF/cglF 308614..309075 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  DV119_RS01855 comGE/cglE 309038..309340 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  DV119_RS01860 comGD/cglD 309303..309707 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  DV119_RS01865 comGC/cglC 309700..310026 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  DV119_RS01870 comGB/cglB 310028..311044 (-) 1017 WP_114880773.1 competence type IV pilus assembly protein ComGB Machinery gene
  DV119_RS01875 comGA/cglA/cilD 310992..311933 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  DV119_RS01880 - 312009..312374 (-) 366 WP_000286415.1 DUF1033 family protein -
  DV119_RS01885 - 312525..313583 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  DV119_RS01890 nagA 313746..314897 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38548.65 Da        Isoelectric Point: 9.8287

>NTDB_id=304613 DV119_RS01870 WP_114880773.1 310028..311044(-) (comGB/cglB) [Streptococcus pneumoniae strain M16808]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETITFLDRSALLDKQCVIQMRAGLSQGKSFSEMMESLGFSSTI
ITQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVRTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=304613 DV119_RS01870 WP_114880773.1 310028..311044(-) (comGB/cglB) [Streptococcus pneumoniae strain M16808]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCACCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGATCCAGATGCGTGCGGGCTTGTCTCAAGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATTTTCAAGCACCATT
ATCACTCAGTTATCCCTAGCTGAAGTTCATGGAAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCTAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCGGACCTATTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

97.337

100

0.973
  comGB/cglB Streptococcus pneumoniae D39

97.337

100

0.973
  comGB/cglB Streptococcus pneumoniae R6

97.337

100

0.973
  comGB/cglB Streptococcus pneumoniae TIGR4

97.337

100

0.973
  comGB/cglB Streptococcus mitis SK321

94.083

100

0.941
  comGB/cglB Streptococcus mitis NCTC 12261

93.787

100

0.938
  comYB Streptococcus gordonii str. Challis substr. CH1

71.131

99.408

0.707
  comYB Streptococcus mutans UA140

57.862

94.083

0.544
  comYB Streptococcus mutans UA159

57.862

94.083

0.544
  comGB Lactococcus lactis subsp. cremoris KW2

51.198

98.817

0.506

Multiple sequence alignment