Detailed information    

insolico Bioinformatically predicted

Overview

Name   ssbA   Type   Machinery gene
Locus tag   DK877_RS02370 Genome accession   NZ_CP030023
Coordinates   448339..448737 (+) Length   132 a.a.
NCBI ID   WP_022540565.1    Uniprot ID   A0A0K2E4A3
Organism   Streptococcus suis strain ISU2414     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 432160..462923 448339..448737 within 0


Gene organization within MGE regions


Location: 432160..462923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK877_RS02250 (DK877_02315) stkP 432160..434154 (+) 1995 WP_009909429.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DK877_RS02255 (DK877_02320) liaF 434611..435270 (+) 660 WP_226964025.1 cell wall-active antibiotics response protein LiaF -
  DK877_RS02260 (DK877_02325) - 435267..436283 (+) 1017 WP_002937028.1 sensor histidine kinase -
  DK877_RS02265 (DK877_02330) - 436255..436896 (+) 642 WP_002937025.1 response regulator transcription factor -
  DK877_RS02270 (DK877_02335) - 436946..438346 (+) 1401 WP_002937018.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DK877_RS02275 (DK877_02340) - 438348..438719 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  DK877_RS02280 (DK877_02345) cysK 438746..439672 (-) 927 WP_002937015.1 cysteine synthase A -
  DK877_RS02285 (DK877_02350) - 439902..441059 (-) 1158 WP_024409220.1 site-specific integrase -
  DK877_RS02290 (DK877_02355) - 441256..441987 (-) 732 WP_013730164.1 hypothetical protein -
  DK877_RS02295 (DK877_02360) - 442035..442418 (-) 384 WP_013730165.1 ImmA/IrrE family metallo-endopeptidase -
  DK877_RS02300 (DK877_02365) - 442425..442973 (-) 549 WP_236685406.1 helix-turn-helix domain-containing protein -
  DK877_RS02305 (DK877_02370) - 442990..443190 (+) 201 WP_002937001.1 helix-turn-helix domain-containing protein -
  DK877_RS02310 (DK877_02375) - 443260..443586 (+) 327 WP_013730166.1 hypothetical protein -
  DK877_RS02315 (DK877_02380) - 443660..443914 (+) 255 WP_013730167.1 hypothetical protein -
  DK877_RS02320 (DK877_02385) - 443970..444203 (+) 234 WP_226960628.1 hypothetical protein -
  DK877_RS02325 - 444193..444345 (+) 153 WP_022540561.1 hypothetical protein -
  DK877_RS02330 (DK877_02390) - 444350..444691 (+) 342 WP_013730169.1 hypothetical protein -
  DK877_RS02335 (DK877_02395) - 444691..445170 (+) 480 WP_013730170.1 siphovirus Gp157 family protein -
  DK877_RS02340 (DK877_02400) - 445167..445412 (+) 246 WP_013730171.1 hypothetical protein -
  DK877_RS02345 (DK877_02405) - 445393..445857 (+) 465 WP_013730172.1 hypothetical protein -
  DK877_RS02350 (DK877_02410) - 445826..446998 (+) 1173 WP_013730173.1 DEAD/DEAH box helicase family protein -
  DK877_RS02355 (DK877_02415) - 447072..447338 (+) 267 WP_226960629.1 hypothetical protein -
  DK877_RS02360 (DK877_02420) - 447348..448046 (+) 699 WP_013730175.1 ERF family protein -
  DK877_RS02365 (DK877_02425) - 448046..448342 (+) 297 WP_022540564.1 hypothetical protein -
  DK877_RS02370 (DK877_02430) ssbA 448339..448737 (+) 399 WP_022540565.1 single-stranded DNA-binding protein Machinery gene
  DK877_RS02375 (DK877_02435) - 448748..449575 (+) 828 WP_013730177.1 bifunctional DNA primase/polymerase -
  DK877_RS02380 (DK877_02440) - 449559..450938 (+) 1380 WP_079253058.1 virulence-associated E family protein -
  DK877_RS02385 - 451295..451450 (+) 156 WP_013730179.1 hypothetical protein -
  DK877_RS02390 (DK877_02445) - 451447..451755 (+) 309 WP_013730180.1 DUF1372 family protein -
  DK877_RS02395 (DK877_02450) - 451757..451972 (+) 216 WP_013730181.1 hypothetical protein -
  DK877_RS02400 (DK877_02455) - 452161..452475 (+) 315 WP_013730182.1 hypothetical protein -
  DK877_RS02405 (DK877_02460) - 452548..452982 (+) 435 WP_002937915.1 DUF1492 domain-containing protein -
  DK877_RS02410 (DK877_02465) - 453079..453426 (+) 348 WP_013730183.1 HNH endonuclease -
  DK877_RS02415 (DK877_02470) - 453515..453877 (+) 363 WP_105203945.1 hypothetical protein -
  DK877_RS02420 (DK877_02475) - 453874..455139 (+) 1266 WP_013730185.1 phage portal protein -
  DK877_RS02425 - 455132..456352 (+) 1221 WP_013730186.1 hypothetical protein -
  DK877_RS02430 (DK877_02485) - 456357..456590 (+) 234 WP_022540567.1 hypothetical protein -
  DK877_RS02435 (DK877_02490) - 456792..457994 (-) 1203 WP_308457548.1 IS110 family transposase -
  DK877_RS11100 (DK877_02495) - 458334..458589 (-) 256 Protein_444 IS110 family transposase -
  DK877_RS11105 - 458898..459185 (+) 288 Protein_445 ISL3 family transposase -
  DK877_RS02440 (DK877_02500) - 459709..460347 (-) 639 WP_009909540.1 MBL fold metallo-hydrolase -
  DK877_RS02445 (DK877_02505) - 460455..462923 (+) 2469 WP_009909541.1 bifunctional DnaQ family exonuclease/ATP-dependent helicase -

Sequence

Protein


Download         Length: 132 a.a.        Molecular weight: 14872.45 Da        Isoelectric Point: 4.6583

>NTDB_id=298474 DK877_RS02370 WP_022540565.1 448339..448737(+) (ssbA) [Streptococcus suis strain ISU2414]
MINNVVLVGRMTRDAELRYTPSNQAVATFTLAVNRNFKNQDGEREADFINVVIWRQQAENLANWAKKGALIGVTGRIQTR
SYDNQQGQRVYVTEVVAESFQLLESRGQQSNSQDGSFGNSSPMDIQDEDLPF

Nucleotide


Download         Length: 399 bp        

>NTDB_id=298474 DK877_RS02370 WP_022540565.1 448339..448737(+) (ssbA) [Streptococcus suis strain ISU2414]
ATGATTAACAATGTAGTACTAGTGGGACGCATGACTCGTGATGCAGAACTTCGTTACACTCCGTCAAACCAGGCGGTTGC
GACTTTTACCTTGGCTGTCAATCGAAACTTCAAAAATCAAGATGGGGAGCGTGAAGCGGACTTTATCAACGTAGTCATTT
GGCGTCAACAAGCTGAGAATTTGGCGAATTGGGCTAAGAAAGGTGCTCTGATTGGTGTTACAGGTCGCATTCAGACTCGT
AGCTATGACAATCAACAAGGGCAACGTGTCTACGTTACTGAGGTAGTTGCAGAAAGTTTCCAACTCTTGGAAAGTCGTGG
ACAACAGTCGAATTCTCAAGACGGATCATTTGGAAATTCAAGTCCTATGGATATCCAAGACGAAGATTTGCCGTTCTAG

Domains

Predicted by InterproScan.

Single-strand binding protein family (SSB)

(2-103)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E4A3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

52.907

100

0.689
  ssb Latilactobacillus sakei subsp. sakei 23K

52.353

100

0.674
  ssbB Streptococcus sobrinus strain NIDR 6715-7

49.242

100

0.492
  ssbB/cilA Streptococcus pneumoniae TIGR4

46.212

100

0.462
  ssbB/cilA Streptococcus mitis NCTC 12261

45.455

100

0.455
  ssbB/cilA Streptococcus pneumoniae Rx1

45.455

100

0.455
  ssbB/cilA Streptococcus pneumoniae D39

45.455

100

0.455
  ssbB/cilA Streptococcus pneumoniae R6

45.455

100

0.455
  ssbB/cilA Streptococcus mitis SK321

45.455

100

0.455
  ssbA Streptococcus mutans UA159

44.697

100

0.447
  ssbB Bacillus subtilis subsp. subtilis str. 168

54.128

82.576

0.447
  ssb Vibrio cholerae strain A1552

29.48

100

0.386
  ssbB Lactococcus lactis subsp. cremoris KW2

48.113

80.303

0.386

Multiple sequence alignment