Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   DK182_RS00885 Genome accession   NZ_CP029491
Coordinates   146382..147329 (+) Length   315 a.a.
NCBI ID   WP_019777327.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 141382..152329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS00870 (DK181_00870) - 142255..142617 (-) 363 WP_019777329.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  DK182_RS00875 (DK181_00875) - 142984..145368 (-) 2385 WP_019777328.1 HAD-IC family P-type ATPase -
  DK182_RS00880 (DK181_00880) - 145588..145956 (+) 369 WP_019781971.1 DUF1033 family protein -
  DK182_RS00885 (DK181_00885) comGA/cglA 146382..147329 (+) 948 WP_019777327.1 competence type IV pilus ATPase ComGA Machinery gene
  DK182_RS00890 (DK181_00890) comYB 147253..148296 (+) 1044 WP_275425199.1 competence type IV pilus assembly protein ComGB Machinery gene
  DK182_RS00895 (DK181_00895) comYC 148293..148619 (+) 327 WP_019777325.1 competence type IV pilus major pilin ComGC Machinery gene
  DK182_RS00900 (DK181_00900) comYD 148573..149007 (+) 435 WP_254051091.1 competence type IV pilus minor pilin ComGD Machinery gene
  DK182_RS00905 (DK181_00905) comYE 148979..149272 (+) 294 WP_002959510.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK182_RS00910 (DK181_00910) comYF 149256..149693 (+) 438 WP_002959513.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK182_RS00915 (DK181_00915) comGG 149671..150132 (+) 462 WP_002959515.1 competence type IV pilus minor pilin ComGG -
  DK182_RS00925 (DK181_00925) - 150334..150600 (+) 267 WP_002959516.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DK182_RS00930 (DK181_00930) - 150587..150862 (+) 276 WP_019777324.1 helix-turn-helix transcriptional regulator -
  DK182_RS00935 (DK181_00935) comYH 150961..151914 (+) 954 WP_019773539.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 315 a.a.        Molecular weight: 35332.67 Da        Isoelectric Point: 6.3082

>NTDB_id=293197 DK182_RS00885 WP_019777327.1 146382..147329(+) (comGA/cglA) [Streptococcus sobrinus strain 10919]
MVEVQELGKELIRQAVEEQAQDIYLLPKPAVYKIYLRFGEKRHLIQTCPPEQAAGLISHFKFLAGMNVGEKRRAQLGACD
YAFADGETAALRLSTVGDYQGRESLVIRLLFDRKRELKFWFDGLNALLPKIIGRGLYLFSGPVGSGKTTLMYELVSRKYP
DSQIITIEDPVEIKQDNMLQLQLNPSIGMTYDHLIKLSLRHRPDVLIIGEIRDRETAQAVIRASLTGIRVFSTVHAKSIP
GVYARILELGVSQDELDNCLAGIAYQRLIGGGGLIDFAQDHFQNHQAECWNEKIDQLLAAGHLTEEEAAAEKIKD

Nucleotide


Download         Length: 948 bp        

>NTDB_id=293197 DK182_RS00885 WP_019777327.1 146382..147329(+) (comGA/cglA) [Streptococcus sobrinus strain 10919]
ATGGTTGAAGTGCAGGAGCTGGGAAAGGAATTGATTAGACAGGCAGTTGAGGAGCAGGCTCAGGATATTTATCTTTTGCC
CAAGCCGGCTGTTTATAAGATTTATCTGCGGTTTGGCGAGAAGCGGCACTTGATTCAGACTTGCCCTCCCGAGCAGGCTG
CGGGTCTGATTAGTCACTTTAAATTTCTTGCTGGCATGAATGTTGGTGAGAAGCGACGGGCCCAGCTGGGTGCCTGTGAT
TATGCCTTCGCTGATGGTGAGACAGCGGCCTTGCGTTTATCGACGGTTGGCGACTATCAAGGGCGAGAAAGTCTGGTTAT
TCGCCTGCTCTTTGACAGAAAACGAGAGTTGAAATTTTGGTTTGATGGTCTAAATGCCCTCCTGCCCAAGATTATCGGGC
GAGGCCTCTACCTTTTTTCTGGACCTGTCGGGTCGGGCAAGACGACCCTCATGTATGAACTGGTCAGTCGCAAGTACCCA
GACAGTCAGATTATTACCATTGAGGATCCTGTTGAGATTAAGCAGGATAATATGCTCCAACTCCAGCTTAATCCCTCTAT
CGGGATGACCTATGACCATTTGATTAAGCTCTCCCTGCGCCATCGGCCGGATGTTCTAATTATCGGAGAAATTCGCGATA
GGGAGACCGCCCAAGCAGTTATTAGGGCTAGCCTAACAGGGATCCGAGTTTTTTCGACTGTTCATGCCAAGAGTATTCCA
GGGGTCTACGCCCGGATTTTAGAGCTGGGTGTTAGCCAGGATGAGTTAGATAATTGTCTGGCCGGCATTGCCTACCAGCG
TTTAATTGGGGGAGGAGGATTGATTGATTTTGCCCAAGACCATTTTCAAAACCACCAGGCTGAGTGCTGGAATGAAAAAA
TTGACCAACTTCTTGCAGCAGGACATCTCACTGAGGAAGAGGCGGCCGCCGAAAAAATTAAAGACTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(11-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

100

100

1
  comYA Streptococcus mutans UA140

66.026

99.048

0.654
  comYA Streptococcus mutans UA159

66.026

99.048

0.654
  comYA Streptococcus gordonii str. Challis substr. CH1

65.705

99.048

0.651
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.581

98.413

0.616
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.581

98.413

0.616
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.581

98.413

0.616
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.581

98.413

0.616
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.258

98.413

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

56.129

98.413

0.552

Multiple sequence alignment